公开(公告)号：US20170199196A1

公开(公告)日：2017-07-13

申请号：US15444679

申请日：2017-02-28

Applicant: STICHTING VU-VUMC

Inventor： Linda Janna Willemien Bosch ,  Meike De Wit ,  Beatriz Pinto Pinto Morais De Carvalho ,  Remond Johannes Adriaan Fijneman ,  Gerrit Albert Meijer ,  Cornelia Ramona Jimenez ,  Sander Rogier Piersma ,  Viet Thang Pham ,  Gideon Oudgenoeg

IPC: G01N33/574

CPC classification number: G01N33/57419 ,  G01N33/6848 ,  G01N2500/10 ,  G01N2570/00 ,  G01N2800/7028

Abstract: The invention provides a method for screening for colorectal cancer, the method comprising: screening a biological sample from an individual for one or more biomarkers selected from the group defined in Table 1 and/or Table 6, wherein the presence of or increased expression of the one or more biomarkers relative to a control sample is indicative that the individual is at risk of suffering from or is suffering from colorectal cancer. The invention also provides an array and kit suitable for use in the methods of the invention, methods of treating colorectal cancer and therapeutic agents for use in methods of treating cancer.