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公开(公告)号:US10947186B2
公开(公告)日:2021-03-16
申请号:US16613822
申请日:2018-05-08
Applicant: STUDIENGESELLSCHAFT KOHLE MBH
Inventor: Tobias Ritter , Fei Ye
IPC: C07C253/12 , B01J31/24 , C07C255/31 , C07C255/34 , C07D213/64 , C07D333/24
Abstract: The present invention refers to a process for a Rh-catalyzed Anti-Markovnikov hydrocyanation of terminal alkynes which process discloses, for the first time, the highly stereo- and regio-selective hydrocyanation of terminal alkynes to furnish E-configured alkenyl nitriles and the catalyst used in the present process.