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公开(公告)号:US20220073552A1
公开(公告)日:2022-03-10
申请号:US17257387
申请日:2019-07-03
Applicant: STUDIENGESELLSCHAFT KOHLE MBH
Inventor: Tobias RITTER , Henrick Jens RICKMEIER
Abstract: The present invention refers to reagents and methods for preparing a peptide sequence having a [18F]fluoro-aromatic amino acid side which may be further substituted, in particular a 4-[18F]fluoro-phenylalanine side chain in peptide sequences, by chemoselective radio-deoxyfluorination of an aromatic amino acid residue, in particular a tyrosine residue using a traceless-activating group and the reagents used in said process.