公开(公告)号：US20200299294A1

公开(公告)日：2020-09-24

申请号：US16897256

申请日：2020-06-09

Applicant: SUNSHINE LAKE PHARMA CO., LTD.

Inventor： Yingjun ZHANG ,  Qingyun REN ,  Changhua TANG ,  Xiaohong LIN ,  Junjun YIN ,  Kai YI

IPC: C07D471/04 ,  C07D519/00 ,  A61K45/06 ,  A61K31/52 ,  A61K31/519 ,  A61K31/517 ,  A61K31/5377 ,  A61K31/506 ,  A61P31/16

Abstract: The invention provides a novel class of compounds as inhibitors of influenza virus replication, preparation methods thereof, pharmaceutical compositions containing these compounds, and uses of these compounds and pharmaceutical compositions thereof in the treatment of influenza.

公开(公告)号：US20200085822A1

公开(公告)日：2020-03-19

申请号：US16467969

申请日：2017-12-14

Applicant: SUNSHINE LAKE PHARMA CO., LTD. ,  NORTH & SOUTH BROTHER PHARMACY INVESTMENT COMPANY LIMITED

Inventor： Changhua TANG ,  Qingyun REN ,  Junjun YIN ,  Kai YI ,  Yibo LEI ,  Yejun WANG ,  Yingjun ZHANG

IPC: A61K31/506 ,  C07D487/04 ,  C07D519/00 ,  A61P31/16

Abstract: The invention provides a class of compounds as inhibitors of influenza virus replication, preparation methods thereof, pharmaceutical compositions containing these compounds, and uses of these compounds and pharmaceutical compositions thereof in the treatment of influenza.

公开(公告)号：US20190194159A1

公开(公告)日：2019-06-27

申请号：US16327335

申请日：2017-08-29

Applicant: SUNSHINE LAKE PHARMA CO., LTD. ,  NORTH & SOUTH BROTHER PHARMACY INVESTMENT COMPANY LIMITED

Inventor： Changhua TANG ,  Qingyun REN ,  Junjun YIN ,  Kai YI ,  Yingjun ZHANG

IPC: C07D401/04 ,  A61K45/06 ,  A61P31/16 ,  C07D405/14 ,  A61K31/4439 ,  C07D471/04 ,  A61K31/444 ,  C07D401/14 ,  C07D417/14 ,  C07D487/04 ,  A61K31/519

CPC classification number: C07D401/04 ,  A61K31/437 ,  A61K31/4439 ,  A61K31/444 ,  A61K31/4985 ,  A61K31/506 ,  A61K31/519 ,  A61K45/06 ,  A61P31/16 ,  C07D401/14 ,  C07D405/14 ,  C07D417/14 ,  C07D471/04 ,  C07D487/04 ,  A61K2300/00

Abstract: The invention provides a novel class of compounds as inhibitors of influenza virus replication, preparation methods thereof, pharmaceutical compositions containing these compounds, and uses of these compounds and pharmaceutical compositions thereof in the manufacture of medicaments for treating of influenza.

公开(公告)号：US20200339564A1

公开(公告)日：2020-10-29

申请号：US16474150

申请日：2018-01-04

Applicant: SUNSHINE LAKE PHARMA CO., LTD.

Inventor： Qingyun REN ,  Changhua TANG ,  Junjun YIN ,  Kai YI ,  Yibo LEI ,  Yejun WANG ,  Yingjun ZHANG

IPC: C07D471/04 ,  C07D519/00 ,  A61K31/506 ,  A61K31/5377 ,  A61K31/519 ,  A61P31/16 ,  A61K31/4965 ,  A61K31/404 ,  A61K31/7056 ,  A61K31/4172 ,  A61K47/64 ,  A61K31/5383 ,  A61K35/76

Abstract: Provided herein is inhibitors of influenza virus replication and uses thereof. Specifically, provided herein a novel class of compounds as inhibitors of influenza virus replication, preparation methods thereof, pharmaceutical compositions containing these compounds, and uses of these compounds and pharmaceutical compositions thereof in the treatment of influenza.

公开(公告)号：US20200283454A1

公开(公告)日：2020-09-10

申请号：US16646072

申请日：2018-09-18

Applicant: SUNSHINE LAKE PHARMA CO., LTD. ,  NORTH & SOUTH BROTHER PHARMACY INVESTMENT COMPANY LIMITED

Inventor： Changhua TANG ,  Qingyun REN ,  Huichao LUO ,  Junjun YIN ,  Kai YI ,  Yibo LEI ,  Yejun WANG ,  Yingjun ZHANG

IPC: C07D498/14 ,  A61K31/5383 ,  A61K45/06 ,  A61K31/554 ,  A61P31/16

Abstract: Disclosed are a compound as shown in formula (I) as an influenza virus replication inhibitor and a preparation method therefor, a pharmaceutical composition comprising the compound and the use of the compound and pharmaceutical composition thereof in the treatment of influenza.

公开(公告)号：US20200010472A1

公开(公告)日：2020-01-09

申请号：US16489587

申请日：2018-03-01

Applicant: SUNSHINE LAKE PHARMA CO., LTD.

Inventor： Changhua TANG ,  Qingyun REN ,  Junjun YIN ,  Kai YI ,  Yibo LEI ,  Yejun WANG ,  Yingjun ZHANG

IPC: C07D487/04 ,  A61P31/16

Abstract: A class of compounds as inhibitors of influenza virus replication, preparation methods thereof, pharmaceutical compositions containing these compounds, and uses of these compounds and pharmaceutical compositions thereof in the treatment of influenza.

公开(公告)号：US20190185456A1

公开(公告)日：2019-06-20

申请号：US16326189

申请日：2017-08-15

Applicant: SUNSHINE LAKE PHARMA CO., LTD.

Inventor： Qingyun REN ,  Changhua TANG ,  Junjun YIN ,  Kai YI ,  Yingjun ZHANG

IPC: C07D403/04 ,  A61K45/06 ,  A61P31/16 ,  A61K31/506 ,  A61K31/5377 ,  C07D487/04 ,  A61K31/519 ,  C07D403/14 ,  C07D417/14 ,  C07D513/04 ,  C07D401/14 ,  C07D405/14 ,  C07D409/14

CPC classification number: C07D403/04 ,  A61K31/04 ,  A61K31/16 ,  A61K31/506 ,  A61K31/519 ,  A61K31/5377 ,  A61K45/06 ,  A61P31/16 ,  C07D401/14 ,  C07D403/14 ,  C07D405/14 ,  C07D409/14 ,  C07D411/14 ,  C07D413/14 ,  C07D417/14 ,  C07D471/04 ,  C07D473/34 ,  C07D487/04 ,  C07D513/04

Abstract: The invention provides a novel class of compounds as inhibitors of influenza virus replication, preparation methods thereof, pharmaceutical compositions containing these compounds, and uses of these compounds and pharmaceutical compositions thereof in the treatment of influenza.

公开(公告)号：US20180346463A1

公开(公告)日：2018-12-06

申请号：US15780231

申请日：2016-12-08

Applicant: SUNSHINE LAKE PHARMA CO., LTD.

Inventor： Yingjun ZHANG ,  Qingyun REN ,  Changhua TANG ,  Xiaohong LIN ,  Junjun YIN ,  Kai YI

IPC: C07D471/04 ,  C07D519/00 ,  A61P31/16 ,  A61K45/06

Abstract: The invention provides a novel class of compounds as inhibitors of influenza virus replication, preparation methods thereof, pharmaceutical compositions containing these compounds, and uses of these compounds and pharmaceutical compositions thereof in the treatment of influenza.