公开(公告)号：US20180072710A1

公开(公告)日：2018-03-15

申请号：US15495019

申请日：2017-04-24

Applicant: SURFACE LOGIX, INC.

Inventor： Alessandra Bartolozzi ,  Stewart Campbell ,  Hope Foudoulakis ,  Brian Kirk ,  Siya Ram ,  Paul Sweetnam ,  Hemalatha Seshardri

IPC: C07D413/14 ,  C07D405/14 ,  B82Y30/00 ,  C07D403/12 ,  C07D401/14 ,  C07D403/14

CPC classification number: C07D413/14 ,  B82Y30/00 ,  C07D401/14 ,  C07D403/12 ,  C07D403/14 ,  C07D405/14

Abstract: The present invention relates to inhibitors of ROCK1 and ROCK2 and methods of modulating the pharmacokinetic and/or pharmacodynamic properties of such compounds. Also provided are methods of inhibiting ROCK1 and or ROCK2 that are useful for the treatment of disease.

公开(公告)号：US20190177311A1

公开(公告)日：2019-06-13

申请号：US16040245

申请日：2018-07-19

Applicant: SURFACE LOGIX, INC.

Inventor： Alessandra Bartolozzi ,  Stewart Campbell ,  Hope Foudoulakis ,  Brian Kirk ,  Siya Ram ,  Paul Sweetnam ,  Hemalatha Seshardri

IPC: C07D413/14 ,  C07D405/14 ,  C07D403/14 ,  B82Y30/00 ,  C07D401/14 ,  C07D403/12

Abstract: The present invention relates to inhibitors of ROCK1 and ROCK2 and methods of modulating the pharmacokinetic and/or pharmacodynamic properties of such compounds. Also provided are methods of inhibiting ROCK1 and or ROCK2 that are useful for the treatment of disease.