公开(公告)号：US3795244A

公开(公告)日：1974-03-05

申请号：US3795244D

申请日：1973-02-02

Applicant: SYNTEX CORP

Inventor： LAX R ,  HERD A

IPC: A61M15/00 ,  A61M15/06

CPC classification number: A61M15/0028 ,  A61M15/0033 ,  A61M2202/064 ,  A61M2206/16

Abstract: An inhalation device having means to engage the free end of a powdered medicament-holding capsule as the capsule is pierced to provide outlet ports for the powdered medicament held therein. Such engagement ensures that the capsule is completely seated in the rotary member on which it is supported and thus ensures that the outlet ports are positioned at the desired locations adjacent the shoulder of the capsule. Additionally, such engagement enables the piercing operation to be conducted in any orientation of the inhalation device. The rotary member, which supports the capsule during inhalation, is itself supported by a shaft having a polygon shaped base having n sides. The rotary member has a hollow sleeve which fits over the shaft, the sleeve having a polygon shaped inner surface having at least n + 1 sides. During inhalation which causes the rotary member to spin about the supporting shaft, contact of the adjacent polygon shaped surfaces with each other positively causes the walls of the capsule to undergo repeated changes or radial acceleration whereby the powdered medicament is dispersed from the capsule.

Abstract translation: 一种吸入装置，其具有在胶囊被刺穿时接合粉末状药物保持胶囊的自由端的装置，以提供保持在其中的粉末状药物的出口。 这种接合确保胶囊完全就位于其所支撑的旋转构件中，从而确保出口端口位于邻近胶囊肩部的所需位置。 此外，这种接合使得能够在吸入装置的任何取向上进行刺穿操作。 在吸入期间支撑胶囊的旋转部件本身由具有n个侧面的多边形基部的轴支撑。 旋转构件具有装配在轴上的中空套筒，套筒具有至少n + 1个侧面的多边形形状的内表面。 在使旋转构件围绕支撑轴旋转的吸入期间，相邻的多边形形状的表面彼此接触积极地导致胶囊的壁经历反复的变化或径向加速，由此粉末状药物从胶囊中分散。