公开(公告)号：US11890268B2

公开(公告)日：2024-02-06

申请号：US17046896

申请日：2019-04-10

申请人： Saint Louis University

发明人： Ryan D. McCulla ,  Ankita Isor ,  Christopher Kent Arnatt

IPC分类号： A61K31/381

CPC分类号： A61K31/381

摘要： In one aspect, the present disclosure provides a compound of the formula: (I) wherein the variables are as defined herein. In another aspect, the present disclosure also provides pharmaceutical compositions and methods of use of the compounds disclosed herein.

公开(公告)号：US12054470B2

公开(公告)日：2024-08-06

申请号：US17046885

申请日：2019-04-10

申请人： Saint Louis University

发明人： Ryan D. McCulla ,  Ankita Isor ,  Christopher Kent Arnatt

IPC分类号： C07D333/76 ,  A61K41/00 ,  A61K45/06 ,  A61P35/00

CPC分类号： C07D333/76 ,  A61K41/0042 ,  A61K45/06 ,  A61P35/00

摘要： In one aspect, the present disclosure provides a compound of the formula: In another aspect, the present disclosure also provides methods of preparing the compounds disclosed herein. In another aspect, the present disclosure also provides pharmaceutical compositions and methods of use of the compounds disclosed herein.