公开(公告)号：US08501917B2

公开(公告)日：2013-08-06

申请号：US13679852

申请日：2012-11-16

Applicant: Samsung Electronics Co., Ltd.

Inventor： Bo-gyou Kim ,  Yun-ju Jeong ,  Kyung-ah Kim ,  Kwang-ho Cheong ,  Seung-hyun Lee

IPC: C07K16/26 ,  C07K16/00 ,  A61K39/395 ,  C07H21/04 ,  C12N1/20 ,  C12N5/20

CPC classification number: C07K16/40 ,  C07K16/2863 ,  C07K2317/21 ,  C07K2317/33 ,  C07K2317/74 ,  C07K2317/75 ,  C07K2317/92

Abstract: An anti c-Met antibody or antigen-binding fragment thereof comprising a heavy-chain variable region having heavy-chain complementarity determining region (CDR) amino acid sequences of SEQ ID NOs: 1, 2 and 3, and a light-chain variable region having light-chain CDR amino acid sequences of SEQ ID NOs: 4, 5, and 6; and a method of wound healing, tissue regeneration, or cell proliferation comprising administration of same; as well as related compositions and methods.

Abstract translation: 包含具有SEQ ID NO：1,2和3的重链互补决定区（CDR）氨基酸序列的重链可变区的抗c-Met抗体或其抗原结合片段和轻链可变区 具有SEQ ID NO：4,5和6的轻链CDR氨基酸序列; 以及伤口愈合，组织再生或细胞增殖的方法，包括施用它们; 以及相关的组合物和方法。