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1.发明授权Sonosensitive liposome, pharmaceutical composition including the same, and method of delivering active agent to subject using the sonosensitive liposome 有权非敏感性脂质体，包含其的药物组合物以及使用超声敏感脂质体将活性剂递送给受试者的方法公开(公告)号：US09220718B2
公开(公告)日：2015-12-29
申请号：US14324818
申请日：2014-07-07
Applicant: Samsung Electronics Co., Ltd.
Inventor： Sun Min Park , Jungyong Nam , Kitae Park , Hyun Ryoung Kim , Eun Sung Park
IPC: A61K9/127 , A61K31/704 , A61K41/00
CPC classification number: A61K31/704 , A61K9/0009 , A61K9/127 , A61K41/0033 , A61K47/26
Abstract: Provided is a liposome comprising a lipid bilayer and a sonosensitizer that is disposed in and/or on the lipid bilayer, wherein the sonosensitizer self-assembles to form aggregates when exposed to ultrasound; and a method of efficiently delivering an active agent to a target site in the body of a subject using the sonosensitive liposome.
Abstract translation: 本发明提供一种脂质体，其包含脂质双层和设置在脂质双层中和/或之上的超声敏敏剂，其中，当暴露于超声波时，所述超声敏敏剂自组装形成聚集体; 以及使用超声敏感脂质体将活性剂有效递送到受试者体内的靶位点的方法。
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公开(公告)号：US09597344B2
公开(公告)日：2017-03-21
申请号：US14830503
申请日：2015-08-19
Applicant: Samsung Electronics Co., Ltd.
Inventor： Sun Min Park , Jungyong Nam , Kitae Park , Hyun Ryoung Kim , Eun Sung Park
IPC: A61K9/127 , A61K31/704 , A61K41/00 , A61K9/00 , A61K47/26
CPC classification number: A61K31/704 , A61K9/0009 , A61K9/127 , A61K41/0033 , A61K47/26
Abstract: Provided is a liposome comprising a lipid bilayer and a sonosensitizer that is disposed in and/or on the lipid bilayer, wherein the sonosensitizer self-assembles to form aggregates when exposed to ultrasound; and a method of efficiently delivering an active agent to a target site in the body of a subject using the sonosensitive liposome.
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3.发明申请SONOSENSITIVE LIPOSOME, PHARMACEUTICAL COMPOSITION INCLUDING THE SAME, AND METHOD OF DELIVERING ACTIVE AGENT TO SUBJECT USING THE SONOSENSITIVE LIPOSOME 有权包括它们的声波脂质体，药物组合物以及使用主要代谢物使用感觉性脂质体的方法公开(公告)号：US20150150971A1
公开(公告)日：2015-06-04
申请号：US14324818
申请日：2014-07-07
Applicant: Samsung Electronics Co., Ltd.
Inventor： Sun Min PARK , Jungyong Nam , Kitae Park , Hyun Ryoung Kim , Eun Sung Park
IPC: A61K41/00 , A61K31/704 , A61K9/127
CPC classification number: A61K31/704 , A61K9/0009 , A61K9/127 , A61K41/0033 , A61K47/26
Abstract: Provided is a liposome comprising a lipid bilayer and a sonosensitizer that is disposed in and/or on the lipid bilayer, wherein the sonosensitizer self-assembles to form aggregates when exposed to ultrasound; and a method of efficiently delivering an active agent to a target site in the body of a subject using the sonosensitive liposome.
Abstract translation: 本发明提供一种脂质体，其包含脂质双层和设置在脂质双层中和/或之上的超声敏敏剂，其中，当暴露于超声波时，所述超声敏敏剂自组装形成聚集体; 以及使用超声敏感脂质体将活性剂有效递送到受试者体内的靶位点的方法。
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