公开(公告)号：US07785823B2

公开(公告)日：2010-08-31

申请号：US11677302

申请日：2007-02-21

Applicant: Sang-jun Sim ,  Chang-deok Kang

Inventor： Sang-jun Sim ,  Chang-deok Kang

IPC: C12P23/00

CPC classification number: C07C403/24 ,  C12P23/00

Abstract: There is provided a method of separating free-astaxanthin selectively from green algae and, more particularly, to a method of separating free-astaxanthin selectively from Haematococcus pluvialis, the method comprising: mixing a cell culture containing Haematococcus pluvialis with an alkanic solvent and stirring, thereby obtaining an alkanic solvent extract containing astaxanthin material including free-astaxanthin and astaxanthin ester (step 1); and mixing the alkanic solvent extract with an alcohol and stirring, thereby obtaining an alcoholic extract containing free-astaxanthin (step 2).

Abstract translation: 提供了一种从绿藻中选择性分离游离虾青素的方法，更具体地说，涉及一种从红潮球菌中选择性分离游离虾青素的方法，该方法包括：将含有积雪球菌的细菌培养物与烷烃溶剂混合并搅拌， 从而得到含有游离虾青素和虾青素的虾青素的烷烃溶剂提取物（步骤1）。 并将该烷醇溶剂提取物与醇混合并搅拌，从而得到含有游离虾青素的醇提取物（步骤2）。

公开(公告)号：US07718355B2

公开(公告)日：2010-05-18

申请号：US11617064

申请日：2006-12-28

Applicant: Sang-jun Sim ,  Chang-deok Kang

Inventor： Sang-jun Sim ,  Chang-deok Kang

IPC: G01N33/553 ,  G01N33/569

CPC classification number: G01N33/569 ,  B82Y15/00 ,  B82Y30/00 ,  G01N33/54373 ,  G01N33/554 ,  Y10S436/805

Abstract: There is provided a method of detecting a pathogenic microorganism in real-time, using a modified flow-type surface plasmon resonance (SPR) biosensor, comprising the steps of: i) performing, in a batch-type, an immune reaction of a pathogenic microorganism and an antibody thereto; ii) selectively separating the pathogenic microorganism bound with the antibody; and iii) binding the pathogenic microorganism bound with the antibody on a surface of a chip of a flow-type SPR sensor system in real-time.

Abstract translation: 提供了一种使用修饰的流式表面等离子体共振（SPR）生物传感器实时检测病原微生物的方法，包括以下步骤：i）以间歇式的方式进行病原体的免疫反应 微生物及其抗体; ii）选择性分离与抗体结合的致病微生物; 和iii）将与抗体结合的病原微生物实时结合在流式SPR传感器系统的芯片的表面上。

公开(公告)号：US20070275371A1

公开(公告)日：2007-11-29

申请号：US11639241

申请日：2006-12-15

Applicant: Sang-jun Sim ,  Sang-wook Lee ,  Dong June Ahn ,  Doo ho Yang

Inventor： Sang-jun Sim ,  Sang-wook Lee ,  Dong June Ahn ,  Doo ho Yang

IPC: C12Q1/70 ,  C07D207/00 ,  G01N33/53 ,  G01N33/566 ,  G01N33/573 ,  G01N33/554 ,  C07D211/72

CPC classification number: G01N33/54353 ,  G01N33/5432

Abstract: There is provided a polydiacetylene supramolecule comprising diacetylene molecules, capable of immobilizing a receptor molecule having a thiol group. Since the polydiacetylene supramolecule has a receptor immobilized thereon having a thiol group, for example, an antibody, and thus shows color transition when reacting with a sample, an antigen can be detected through specific color transition of the polydiacetylene when employing in a receptor-ligand reaction, for example, an antibody-antigen reaction.

Abstract translation: 提供了包含能够固定具有硫醇基的受体分子的二乙炔分子的聚二乙炔超分子。 由于聚二乙炔超分子具有固定在其上的受体，例如具有硫醇基的受体，例如抗体，因此当与样品反应时显示颜色转变，当在受体配体中使用时，可以通过聚二乙炔的特定颜色转变来检测抗原 反应，例如抗体 - 抗原反应。

公开(公告)号：US07776554B2

公开(公告)日：2010-08-17

申请号：US11639241

申请日：2006-12-15

Applicant: Sang-jun Sim ,  Sang-wook Lee ,  Dong June Ahn ,  Doo ho Yang

Inventor： Sang-jun Sim ,  Sang-wook Lee ,  Dong June Ahn ,  Doo ho Yang

IPC: G01N33/53 ,  G01N33/551 ,  G01N33/544 ,  G01N21/76 ,  C12P7/40

CPC classification number: G01N33/54353 ,  G01N33/5432

Abstract: There is provided a polydiacetylene supramolecule comprising diacetylene molecules, capable of immobilizing a receptor molecule having a thiol group. Since the polydiacetylene supramolecule has a receptor immobilized thereon having a thiol group, for example, an antibody, and thus shows color transition when reacting with a sample, an antigen can be detected through specific color transition of the polydiacetylene when employing in a receptor-ligand reaction, for example, an antibody-antigen reaction.

Abstract translation: 提供了包含能够固定具有硫醇基的受体分子的二乙炔分子的聚二乙炔超分子。 由于聚二乙炔超分子具有固定在其上的受体，例如具有硫醇基的受体，例如抗体，因此当与样品反应时显示颜色转变，当在受体配体中使用时，可以通过聚二乙炔的特定颜色转变来检测抗原 反应，例如抗体 - 抗原反应。