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公开(公告)号:US08748431B2
公开(公告)日:2014-06-10
申请号:US13989797
申请日:2011-11-25
申请人: Sarah Sulzer-Mosse , Clemens Lamberth , Mathias Stephan Respondek , Laura Quaranta , Fredrik Cederbaum , Guillaume Berthon
发明人: Sarah Sulzer-Mosse , Clemens Lamberth , Mathias Stephan Respondek , Laura Quaranta , Fredrik Cederbaum , Guillaume Berthon
IPC分类号: A61K31/497 , A61K31/4523 , A61K31/4427 , A61K31/41 , A61K31/42 , C07D401/14 , C07D241/36 , C07D413/14 , C07D285/06 , C07D261/06
CPC分类号: A01N43/82 , A01N43/60 , A01N43/80 , C07D401/14 , C07D413/14 , C07D417/14 , C07D513/04
摘要: Compounds of the formula I Formula (I) wherein the substituents are as defined in claim 1, are useful as active ingredients, which have microbiocidal activity, in particular fungicidal activity.
摘要翻译: 其中取代基如权利要求1中所定义的式I化学式(I)的化合物可用作具有杀微生物活性,特别是杀真菌活性的活性成分。
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公开(公告)号:US08557821B2
公开(公告)日:2013-10-15
申请号:US13390036
申请日:2010-08-05
IPC分类号: A61K31/497 , A61K31/454 , C07D403/04 , C07D401/04
CPC分类号: C07D413/14 , A01N43/76 , A01N43/78 , A01N43/82 , C07D263/48 , C07D277/28 , C07D285/08 , C07D413/04 , C07D417/04 , C07D417/14
摘要: The present invention relates to heterocyclic compounds of formula (I) which have microbiocidal activity, in particular fungicidal activity, as well as methods of using the compounds of formula (I) to control microbes.
摘要翻译: 本发明涉及具有杀微生物活性,特别是杀真菌活性的式(I)的杂环化合物,以及使用式(I)化合物来控制微生物的方法。
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公开(公告)号:US08367844B2
公开(公告)日:2013-02-05
申请号:US13390023
申请日:2010-08-06
IPC分类号: A01N43/40 , A01N43/36 , A01N43/54 , A01N43/56 , A01N43/60 , C07D401/02 , C07D401/14 , C07D403/02 , C07D403/14 , C07D207/04 , C07D231/10 , C07D241/04
CPC分类号: C07D401/14 , C07D231/12 , C07D401/04 , C07D401/06 , C07D401/12
摘要: The present invention relates to heterocyclic compounds of formula I which have microbiocidal activity, in particular fungicidal activity as well as methods of using the compounds of formula (I) to control microbes: wherein A is x-C(R10R11)—C(═O)—, x-C(R12R13)—C(═S)—, x-O—C(═O)—, x-O—C(═S)—, x-N(R14)—C(═O)—, x-N(R15)—C(═S)—, x-C(R16R17)—SO2— or X—N═C(R30)—, in each case x indicates the bond that is connected to R1; T is CR18 or N; Y1, Y2, Y3, and Y4 are independently CR19 or N; Q is O or S; n is 1 or 2; p is 1 or 2, providing that when n is 2, p is 1. R1 is phenyl, pyridyl, imidazolyl, or pyrazolyl; wherein the phenyl, pyridyl, imidazolyl and pyrazolyl are each optionally substituted by 1 to 3 substituents independently selected from C1-C4 alkyl, C1-C4 haloalkyl, halogen, cyano, hydroxy and amino; R2, R3, R4, R5, R6, R7, R10, R11, R12, R13, R16, R17, R18, R19 and R30 each independently are hydrogen, halogen, cyano, C1-C4alkyl, or C1-C4haloalkyl; R8, R14 and R15 each independently are hydrogen or C1-C4alkyl; and R9 is phenyl, benzyl or group (a): wherein the phenyl, benzyl and group (a) are each optionally substituted with 1 to 3 substituents independently selected from C1-C4 alkyl, C1-C4 haloalkyl, halogen, cyano, hydroxy and amino; or a salt or a N-oxide thereof.
摘要翻译: 本发明涉及具有杀微生物活性,特别是杀真菌活性的式I的杂环化合物以及使用式(I)化合物来控制微生物的方法:其中A是xC(R10R11)-C(= O) - ,xC(R12R13)-C(= S) - ,xO-C(= O) - ,xO-C(= S) - ,xN(R14)-C(= O) - ,xN(R15)-C (X)(R 16 R 17)-SO 2 - 或X-N = C(R 30) - ,在各种情况下,x表示与R1连接的键; T为CR18或N; Y1,Y2,Y3和Y4独立地为CR19或N; Q是O或S; n为1或2; p为1或2,条件是当n为2时,p为1. R1为苯基,吡啶基,咪唑基或吡唑基; 其中苯基,吡啶基,咪唑基和吡唑基各自任选被1至3个独立地选自C 1 -C 4烷基,C 1 -C 4卤代烷基,卤素,氰基,羟基和氨基的取代基取代; R2,R3,R4,R5,R6,R7,R10,R11,R12,R13,R16,R17,R18,R19和R30各自独立地为氢,卤素,氰基,C1-C4烷基或C1-C4卤代烷基; R8,R14和R15各自独立地为氢或C1-C4烷基; 并且R 9为苯基,苄基或基团(a):其中苯基,苄基和基团(a)各自任选被1至3个独立地选自C 1 -C 4烷基,C 1 -C 4卤代烷基,卤素,氰基,羟基和 氨基; 或其盐或N-氧化物。
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公开(公告)号:US20130324544A1
公开(公告)日:2013-12-05
申请号:US13989797
申请日:2011-11-25
申请人: Sarah Sulzer-Mosse , Clemens Lamberth , Mathias Stephan Respondek , Laura Quaranta , Fredrik Cederbaum , Guillaume Berthon
发明人: Sarah Sulzer-Mosse , Clemens Lamberth , Mathias Stephan Respondek , Laura Quaranta , Fredrik Cederbaum , Guillaume Berthon
CPC分类号: A01N43/82 , A01N43/60 , A01N43/80 , C07D401/14 , C07D413/14 , C07D417/14 , C07D513/04
摘要: Compounds of the formula I Formula (I) wherein the substituents are as defined in claim 1, are useful as active ingredients, which have microbiocidal activity, in particular fungicidal activity.
摘要翻译: 其中取代基如权利要求1中所定义的式I化学式(I)的化合物可用作具有杀微生物活性,特别是杀真菌活性的活性成分。
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公开(公告)号:US20120142698A1
公开(公告)日:2012-06-07
申请号:US13390023
申请日:2010-08-06
IPC分类号: A01N43/60 , C07D207/09 , C07D207/48 , C07D401/14 , C07D401/04 , A01P3/00 , C07D403/04 , A01N43/56 , A01N43/36 , A01N43/40 , A01N43/54 , C07D403/06 , C07D403/14
CPC分类号: C07D401/14 , C07D231/12 , C07D401/04 , C07D401/06 , C07D401/12
摘要: The present invention relates to heterocyclic compounds of formula I which have microbiocidal activity, in particular fungicidal activity as well as methods of using the compounds of formula (I) to control microbes: wherein A is x-C(R10R11)—C(═O)—, x-C(R12R13)—C(═S)—, x-O—C(═O)—, x-O—C(═S)—, x-N(R14)—C(═O)—, x-N(R15)—C(═S)—, x-C(R16R17)—SO2— or X—N═C(R30)—, in each case x indicates the bond that is connected to R1; T is CR18 or N; Y1, Y2, Y3, and Y4 are independently CR19 or N; Q is O or S; n is 1 or 2; p is 1 or 2, providing that when n is 2, p is 1. R1 is phenyl, pyridyl, imidazolyl, or pyrazolyl; wherein the phenyl, pyridyl, imidazolyl and pyrazolyl are each optionally substituted by 1 to 3 substituents independently selected from C1-C4 alkyl, C1-C4 haloalkyl, halogen, cyano, hydroxy and amino; R2, R3, R4, R5, R6, R7, R10, R11, R12, R13, R16, R17, R18, R19 and R30 each independently are hydrogen, halogen, cyano, C1-C4alkyl, or C1-C4haloalkyl; R8, R14 and R15 each independently are hydrogen or C1-C4alkyl; and R9 is phenyl, benzyl or group (a): wherein the phenyl, benzyl and group (a) are each optionally substituted with 1 to 3 substituents independently selected from C1-C4 alkyl, C1-C4 haloalkyl, halogen, cyano, hydroxy and amino; or a salt or a N-oxide thereof.
摘要翻译: 本发明涉及具有杀微生物活性,特别是杀真菌活性的式I的杂环化合物以及使用式(I)化合物来控制微生物的方法:其中A是xC(R10R11)-C(= O) - ,xC(R12R13)-C(= S) - ,xO-C(= O) - ,xO-C(= S) - ,xN(R14)-C(= O) - ,xN(R15)-C (X)(R 16 R 17)-SO 2 - 或X-N = C(R 30) - ,在各种情况下,x表示与R1连接的键; T为CR18或N; Y1,Y2,Y3和Y4独立地为CR19或N; Q是O或S; n为1或2; p为1或2,条件是当n为2时,p为1. R1为苯基,吡啶基,咪唑基或吡唑基; 其中苯基,吡啶基,咪唑基和吡唑基各自任选被1至3个独立地选自C 1 -C 4烷基,C 1 -C 4卤代烷基,卤素,氰基,羟基和氨基的取代基取代; R2,R3,R4,R5,R6,R7,R10,R11,R12,R13,R16,R17,R18,R19和R30各自独立地为氢,卤素,氰基,C1-C4烷基或C1-C4卤代烷基; R8,R14和R15各自独立地为氢或C1-C4烷基; 并且R 9为苯基,苄基或基团(a):其中苯基,苄基和基团(a)各自任选被1至3个独立地选自C 1 -C 4烷基,C 1 -C 4卤代烷基,卤素,氰基,羟基和 氨基; 或其盐或N-氧化物。
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公开(公告)号:US20120142700A1
公开(公告)日:2012-06-07
申请号:US13390036
申请日:2010-08-05
IPC分类号: A01N43/78 , C07D417/04 , A01P3/00 , C07D413/04 , A01N43/836 , A01N43/76 , C07D417/14 , C07D413/14
CPC分类号: C07D413/14 , A01N43/76 , A01N43/78 , A01N43/82 , C07D263/48 , C07D277/28 , C07D285/08 , C07D413/04 , C07D417/04 , C07D417/14
摘要: The present invention relates to heterocyclic compounds of formula (I) which have microbiocidal activity, in particular fungicidal activity, as well as methods of using the compounds of formula (I) to control microbes.
摘要翻译: 本发明涉及具有杀微生物活性,特别是杀真菌活性的式(I)的杂环化合物,以及使用式(I)化合物来控制微生物的方法。
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公开(公告)号:US09301530B2
公开(公告)日:2016-04-05
申请号:US14127598
申请日:2012-06-27
IPC分类号: A01N43/56 , A01N43/60 , C07D401/06 , C07D401/12 , C07D401/14 , C07D403/06 , C07D403/12 , C07D403/14
CPC分类号: A01N43/60 , A01N43/56 , C07D401/06 , C07D401/12 , C07D401/14 , C07D403/06 , C07D403/12 , C07D403/14
摘要: The present invention relates to heterocyclic compounds of formula I which have microbiocidal activity, in particular fungicidal activity as well as methods of using the compounds of formula (I) to control microbes: wherein A is x-C(R10R11)—C(═O)—, x-C(R12R13)—C(═S)—, x-O—C(═O)—, x-O—C(═S)—, x-N(R14)—C(═O)—, x-N(R15)—C(═S)—, x-C(R16R17)—SO2— or x-N═C(R30)—, in each case x indicates the bond that is connected to R1; T is CR18 or N; Y1, Y2, Y3, and Y4 are independently CR19 or N; Q is O or S; n is 1 or 2; p is 1 or 2, providing that when n is 2, p is 1. R1 is (formula A) R2, R3, R4, R5, R6, R7, R10, R11, R12, R13, R16, R17, R18, R19 and R30 each independently are hydrogen, halogen, cyano, C1-C4alkyl, or C1-C4haloalkyl; R8, R14 and R15 each independently are hydrogen or C1-C4alkyl; and R9 is phenyl, benzyl or group (a), wherein the phenyl, benzyl and group (a) are each optionally substituted with 1 to 3 substituents independently selected from C1-C4 alkyl, C1-C4 haloalkyi, halogen, cyano, hydroxy and amino; or a salt or a N-oxide thereof.
摘要翻译: 本发明涉及具有杀微生物活性,特别是杀真菌活性的式I的杂环化合物以及使用式(I)化合物来控制微生物的方法:其中A是xC(R10R11)-C(= O) - ,xC(R12R13)-C(= S) - ,xO-C(= O) - ,xO-C(= S) - ,xN(R14)-C(= O) - ,xN(R15)-C ≡S) - ,xC(R16R17)-SO2-或xN = C(R30) - ,在各种情况下x表示与R1连接的键; T为CR18或N; Y1,Y2,Y3和Y4独立地为CR19或N; Q是O或S; n为1或2; p为1或2,条件是当n为2时,p为1. R1为(式A)R2,R3,R4,R5,R6,R7,R10,R11,R12,R13,R16,R17,R18,R19 R 30各自独立地为氢,卤素,氰基,C 1 -C 4烷基或C 1 -C 4卤代烷基; R8,R14和R15各自独立地为氢或C1-C4烷基; 并且R 9为苯基,苄基或基团(a),其中苯基,苄基和基团(a)各自任选被1至3个独立地选自C 1 -C 4烷基,C 1 -C 4卤代烷基,卤素,氰基,羟基和 氨基; 或其盐或N-氧化物。
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公开(公告)号:US20140228372A1
公开(公告)日:2014-08-14
申请号:US14349721
申请日:2012-09-14
CPC分类号: A01N43/78 , A01N43/82 , C07D417/14
摘要: The present invention relates to compounds of formula (I) wherein R1, R2, R3, R4, R5, R6, R7, R8, R9, R10, R11, R12, R13, G1, G2, G3, Y1, Y2, n, and p are as defined in the claims. The invention also relates to methods of using the compounds of formula (I) to control or prevent infestation of plants, propagation material thereof, harvested crops or non-living materials by phytopathogenic spoilage microorganisms or organisms potentially harmful to man.
摘要翻译: 本发明涉及式(I)化合物,其中R1,R2,R3,R4,R5,R6,R7,R8,R9,R10,R11,R12,R13,G1,G2,G3,Y1,Y2, 和p如权利要求中所定义。 本发明还涉及使用式(I)化合物通过植物病原性腐败微生物或对人体有害的生物来控制或预防植物,繁殖材料,收获作物或非生物材料的侵染的方法。
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公开(公告)号:US08748432B2
公开(公告)日:2014-06-10
申请号:US13984449
申请日:2012-02-08
IPC分类号: A61K31/497 , A61K31/4523 , C07D403/14 , C07D401/14
CPC分类号: A01N43/56 , A01N43/58 , A01N43/60 , C07D231/12 , C07D401/06 , C07D401/12 , C07D401/14 , C07D403/06 , C07D403/12 , C07D403/14 , C07D405/14 , C07D409/14 , C07D417/14
摘要: The present invention provides compounds of formula (I): wherein the substituents are as defined in claim 1, are useful as active ingredients, which have microbiocidal activity, in particular fungicidal activity.
摘要翻译: 本发明提供式(I)化合物:其中取代基如权利要求1中所定义,可用作活性成分,其具有杀微生物活性,特别是杀真菌活性。
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公开(公告)号:US20140243371A1
公开(公告)日:2014-08-28
申请号:US14349766
申请日:2012-09-14
申请人: Jayant Umarye , Guillaume Berthon , Fredrik Emil Malcolm Cederbaum , Torsten Luksch , Clemens Lamberth , Sarah Sulzer-Mosse , Pranab Kanjilal , Ravindra Sonawane
发明人: Jayant Umarye , Guillaume Berthon , Fredrik Emil Malcolm Cederbaum , Torsten Luksch , Clemens Lamberth , Sarah Sulzer-Mosse , Pranab Kanjilal , Ravindra Sonawane
IPC分类号: A01N43/56 , C07D401/06
CPC分类号: A01N43/56 , C07D401/06 , C07D417/04 , C07D417/14
摘要: The present invention relates to compounds of formula (I) wherein R1, R2, R3, R4, R5, R6, R7, R8, R9, R10, R11, R12, R13, G1, G2, G3, Y1, Y2, n, and p are as defined in the claims. The invention also relates to methods of using the compounds of formula I to control or prevent infestation of plants, propagation material thereof, harvested crops or non-living materials by phytopathogenic or spoilage microorganisms or organisms potentially harmful to man.
摘要翻译: 本发明涉及其中R1,R2,R3,R4,R5,R6,R7,R8,R9,R10,R11,R12,R13,G1,G2,G3,Y1,Y2, 和p如权利要求中所定义。 本发明还涉及使用式I化合物来控制或防止植物,繁殖材料,收获作物或非生物材料通过植物病原性或腐败性微生物或对人体有害的生物的侵害。
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