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    High-resolution retinal imaging using adaptive optics and Fourier-domain optical coherence tomography
    1.
    发明授权
    High-resolution retinal imaging using adaptive optics and Fourier-domain optical coherence tomography 有权
    使用自适应光学和傅立叶域光学相干断层扫描的高分辨率视网膜成像

    公开(公告)号：US07791734B2

    公开(公告)日：2010-09-07

    申请号：US11417074

    申请日：2006-05-02

    申请人： Scot S. Olivier ,  John S. Werner ,  Robert J. Zawadzki ,  Sophie P. Laut ,  Steven M. Jones

    发明人： Scot S. Olivier ,  John S. Werner ,  Robert J. Zawadzki ,  Sophie P. Laut ,  Steven M. Jones

    IPC分类号： G01B9/02

    CPC分类号： A61B3/14 ,  A61B3/102

    摘要： This invention permits retinal images to be acquired at high speed and with unprecedented resolution in three dimensions (4×4×6 μm). The instrument achieves high lateral resolution by using adaptive optics to correct optical aberrations of the human eye in real time. High axial resolution and high speed are made possible by the use of Fourier-domain optical coherence tomography. Using this system, we have demonstrated the ability to image microscopic blood vessels and the cone photoreceptor mosaic.

    摘要翻译： 本发明允许在三维（4×4×6μm）中以高速和前所未有的分辨率获得视网膜图像。 该仪器通过使用自适应光学器件实时校正人眼的光学像差来实现高横向分辨率。 通过使用傅里叶域光学相干断层扫描可以实现高轴向分辨率和高速度。 使用该系统，我们已经展示了对微观血管和圆锥感光体镶嵌进行成像的能力。

    High-resolution Adaptive Optics Scanning Laser Ophthalmoscope with Multiple Deformable Mirrors
    6.
    发明申请
    High-resolution Adaptive Optics Scanning Laser Ophthalmoscope with Multiple Deformable Mirrors 失效
    高分辨率自适应光学扫描激光眼镜与多变形镜

    公开(公告)号：US20080218694A1

    公开(公告)日：2008-09-11

    申请号：US11874832

    申请日：2007-10-18

    申请人： Diana C. Chen ,  Scot S. Olivier ,  Steven M. Jones

    发明人： Diana C. Chen ,  Scot S. Olivier ,  Steven M. Jones

    IPC分类号： A61B3/14

    CPC分类号： G02B27/0068 ,  A61B3/1025 ,  G02B26/0833 ,  G02B27/40

    摘要： An adaptive optics scanning laser opthalmoscopes is introduced to produce non-invasive views of the human retina. The use of dual deformable mirrors improved the dynamic range for correction of the wavefront aberrations compared with the use of the MEMS mirror alone, and improved the quality of the wavefront correction compared with the use of the bimorph mirror alone. The large-stroke bimorph deformable mirror improved the capability for axial sectioning with the confocal imaging system by providing an easier way to move the focus axially through different layers of the retina.

    摘要翻译： 引入自适应光学扫描激光眼镜以产生人视网膜的非侵入性视图。 与单独使用MEMS镜相比，使用双变形反射镜改善了用于校正波前像差的动态范围，并且与单独使用双压电晶片镜相比，改善了波前校正的质量。 大中压双压电晶片可变形反射镜通过提供一种更容易的方式将焦点轴向移动到视网膜的不同层，提高了用共轴成像系统轴向切片的能力。

    High-resolution adaptive optics scanning laser ophthalmoscope with multiple deformable mirrors
    7.
    发明授权
    High-resolution adaptive optics scanning laser ophthalmoscope with multiple deformable mirrors 失效
    具有多个可变形反射镜的高分辨率自适应光学扫描激光检眼镜

    公开(公告)号：US07665844B2

    公开(公告)日：2010-02-23

    申请号：US11874832

    申请日：2007-10-18

    申请人： Diana C. Chen ,  Scot S. Olivier ,  Steven M. Jones

    发明人： Diana C. Chen ,  Scot S. Olivier ,  Steven M. Jones

    IPC分类号： A61B3/14 ,  A61B3/10 ,  A61B3/00

    CPC分类号： G02B27/0068 ,  A61B3/1025 ,  G02B26/0833 ,  G02B27/40

    摘要： An adaptive optics scanning laser ophthalmoscopes is introduced to produce non-invasive views of the human retina. The use of dual deformable mirrors improved the dynamic range for correction of the wavefront aberrations compared with the use of the MEMS mirror alone, and improved the quality of the wavefront correction compared with the use of the bimorph mirror alone. The large-stroke bimorph deformable mirror improved the capability for axial sectioning with the confocal imaging system by providing an easier way to move the focus axially through different layers of the retina.

    摘要翻译： 引入自适应光学扫描激光眼镜以产生人视网膜的非侵入性视图。 与单独使用MEMS镜相比，使用双变形反射镜改善了用于校正波前像差的动态范围，并且与单独使用双压电晶片镜相比，改善了波前校正的质量。 大中压双压电晶片可变形反射镜通过提供一种更容易的方式将焦点轴向移动到视网膜的不同层，提高了用共轴成像系统轴向切片的能力。

    High-resolution ophthalmic imaging system
    8.
    发明授权
    High-resolution ophthalmic imaging system 有权
    高分辨率眼科成像系统

    公开(公告)号：US07303280B2

    公开(公告)日：2007-12-04

    申请号：US11017384

    申请日：2004-12-17

    申请人： Scot S. Olivier ,  Carmen J. Carrano

    发明人： Scot S. Olivier ,  Carmen J. Carrano

    IPC分类号： A61B3/14

    CPC分类号： A61B3/14 ,  A61B3/12

    摘要： A system for providing an improved resolution retina image comprising an imaging camera for capturing a retina image and a computer system operatively connected to the imaging camera, the computer producing short exposures of the retina image and providing speckle processing of the short exposures to provide the improved resolution retina image. The system comprises the steps of capturing a retina image, producing short exposures of the retina image, and speckle processing the short exposures of the retina image to provide the improved resolution retina image.

    摘要翻译： 一种用于提供改进的分辨率视网膜图像的系统，包括用于捕获视网膜图像的成像相机和可操作地连接到成像相机的计算机系统，所述计算机产生视网膜图像的短曝光并且提供短曝光的斑点处理以提供改进的 分辨率视网膜图像。 该系统包括捕获视网膜图像，产生视网膜图像的短曝光和斑点处理视网膜图像的短曝光以提供改进的分辨率视网膜图像的步骤。

    SCHEDULER FOR MONITORING OBJECTS ORBITING EARTH USING SATELLITE-BASED TELESCOPES
    10.
    发明申请
    SCHEDULER FOR MONITORING OBJECTS ORBITING EARTH USING SATELLITE-BASED TELESCOPES 有权
    使用基于卫星电视机监控对象的地面监视器

    公开(公告)号：US20130275036A1

    公开(公告)日：2013-10-17

    申请号：US13559449

    申请日：2012-07-26

    申请人： Scot S. Olivier ,  Alexander J. Pertica ,  Vincent J. Riot ,  Willem H. De Vries ,  Brian J. Bauman ,  Sergei Nikolaev ,  John R. Henderson ,  Donald W. Phillion

    发明人： Scot S. Olivier ,  Alexander J. Pertica ,  Vincent J. Riot ,  Willem H. De Vries ,  Brian J. Bauman ,  Sergei Nikolaev ,  John R. Henderson ,  Donald W. Phillion

    IPC分类号： G08G5/04 ,  B64G1/10

    CPC分类号： B64G1/242 ,  B64G1/1085 ,  B64G1/36 ,  B64G3/00

    摘要： An ephemeris refinement system includes satellites with imaging devices in earth orbit to make observations of space-based objects (“target objects”) and a ground-based controller that controls the scheduling of the satellites to make the observations of the target objects and refines orbital models of the target objects. The ground-based controller determines when the target objects of interest will be near enough to a satellite for that satellite to collect an image of the target object based on an initial orbital model for the target objects. The ground-based controller directs the schedules to be uploaded to the satellites, and the satellites make observations as scheduled and download the observations to the ground-based controller. The ground-based controller then refines the initial orbital models of the target objects based on the locations of the target objects that are derived from the observations.

    摘要翻译： 星历细化系统包括具有地球轨道中的成像设备的卫星，以观测基于空间的物体（“目标物体”）和地面控制器，其控制卫星的调度以对目标物体进行观测并且精炼轨道 目标对象的模型。 基于地面的控制器基于目标对象的初始轨道模型确定目标物体何时将足够靠近该卫星的卫星以收集目标对象的图像。 地面控制器将上传的时间表指定到卫星，卫星按计划进行观察，并将观测资料下载到地面控制器。 然后，基于地面的控制器基于从观测得到的目标对象的位置来优化目标对象的初始轨道模型。