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公开(公告)号:US20070134675A1
公开(公告)日:2007-06-14
申请号:US11297712
申请日:2005-12-08
CPC分类号: C12Q1/6883 , C12Q1/6851 , C12Q2600/106 , C12Q2600/142 , C12Q2600/156 , C12Q2600/16
摘要: Methods are described for determining sulfonator status of a patient and determining dosages of drugs based on copy number of the SULT1A1 gene.
摘要翻译: 描述了用于确定患者的磺化物状态的方法,并且基于SULT1A1基因的拷贝数确定药物的剂量。
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公开(公告)号:US20070178493A1
公开(公告)日:2007-08-02
申请号:US11559548
申请日:2006-11-14
CPC分类号: C12Q1/6883 , C12Q1/6851 , C12Q2600/156 , C12Q2600/16 , C12Q2600/172
摘要: Methods are described for determining sulfonator status of a patient and determining dosages of drugs based on copy number of the SULT1A1 gene.
摘要翻译: 描述了用于确定患者的磺化物状态的方法,并且基于SULT1A1基因的拷贝数确定药物的剂量。
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公开(公告)号:US20070037177A1
公开(公告)日:2007-02-15
申请号:US11206251
申请日:2005-08-16
申请人: Richard Weinshilboum , Eric Wieben , Oreste Salavaggione , Araba Adjei , Linda Pelleymounter , Josefa Coronel , Liewei Wang , Bruce Eckloff , Daniel Schaid , Cynthia Ma
发明人: Richard Weinshilboum , Eric Wieben , Oreste Salavaggione , Araba Adjei , Linda Pelleymounter , Josefa Coronel , Liewei Wang , Bruce Eckloff , Daniel Schaid , Cynthia Ma
CPC分类号: C12Q1/6883 , C12Q2600/106 , C12Q2600/156 , C12Q2600/172
摘要: Isolated CYP19A1 nucleic acid molecules that include a nucleotide sequence variant and nucleotides flanking the sequence variant are described, as well as CYP19A1 allozymes. Methods for determining the aromatase status of an individual also are provided, as are methods for determining if a subject is predisposed to certain clinical conditions.
摘要翻译: 描述了包含核苷酸序列变体和序列变体侧翼核苷酸的分离的CYP19A1核酸分子,以及CYP19A1同工酶。 还提供了确定个体芳香化酶状态的方法,以及用于确定受试者是否易患某些临床状况的方法。
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