公开(公告)号：US07433739B1

公开(公告)日：2008-10-07

申请号：US11001374

申请日：2004-11-30

申请人： Scott Salys ,  Chris Parrillo ,  Matt Phillips ,  Luz Padilla ,  Jnyan Patel ,  Kevin L. Morgan ,  Michael Yang ,  Sheldon Williams ,  Andrew W. McGarvey

发明人： Scott Salys ,  Chris Parrillo ,  Matt Phillips ,  Luz Padilla ,  Jnyan Patel ,  Kevin L. Morgan ,  Michael Yang ,  Sheldon Williams ,  Andrew W. McGarvey

IPC分类号： A61N1/05

CPC分类号： A61N1/0587

摘要： An implantable lead having an elongated lead body that includes an electrical conductor extending between a distal end of the lead body and a proximal end of the lead body is disclosed. The lead further includes an electrode formed at the distal end of the lead body, the electrode being coupled to the electrical conductor and one or more passive fixation mesh sections coupled to the distal end of the lead body that promotes tissue over growth.

摘要翻译： 公开了一种具有细长引线主体的可植入引线，其包括在引线主体的远端和引线主体的近端之间延伸的电导体。 引线还包括形成在引线主体的远端处的电极，电极耦合到电导体和耦合到引线主体的远端的一个或多个被动固定网孔部分，其促进组织过度生长。

公开(公告)号：US07369901B1

公开(公告)日：2008-05-06

申请号：US11056666

申请日：2005-02-10

申请人： Kevin L. Morgan ,  John R. Helland ,  Sheldon Williams ,  Yougandh Chitre ,  Andrew W. McGarvey ,  Christopher Fleck ,  Jnyan Patel ,  Scott Salys ,  Kerwyn Schimke

发明人： Kevin L. Morgan ,  John R. Helland ,  Sheldon Williams ,  Yougandh Chitre ,  Andrew W. McGarvey ,  Christopher Fleck ,  Jnyan Patel ,  Scott Salys ,  Kerwyn Schimke

IPC分类号： A61N1/362 ,  A61N1/05

CPC分类号： A61N1/059

摘要： An implantable myocardial stimulation lead comprises a lead body having a distal end and a proximal end, and an electrical connector carried by the proximal end of the lead body. An electrode header carried by the distal end of the lead body has an axis and includes a helical fixation element extending along the axis, the electrode header having a surface configured to receive a driver for rotating the electrode header to screw the helical fixation element into the tissue of the heart. The lead body carries along its length a strain relief member resisting excessive bending of the lead body.

摘要翻译： 植入式心肌刺激引线包括具有远端和近端的引线主体和由引线主体的近端承载的电连接器。 由引线主体的远端承载的电极头具有轴线并且包括沿着轴线延伸的螺旋固定元件，电极头具有被配置为接收驱动器的表面，该驱动器用于旋转电极头以将螺旋固定元件拧入 心脏的组织 引线体沿其长度方向承载抵抗引线体的过度弯曲的应变消除部件。

公开(公告)号：US08538555B1

公开(公告)日：2013-09-17

申请号：US12973810

申请日：2010-12-20

申请人： Yougandh Chitre ,  Gene A. Bornzin ,  John R. Helland ,  Eric Falkenberg ,  Kevin L. Morgan ,  Sheldon Williams ,  Michael Yang ,  Andrew W. McGarvey

发明人： Yougandh Chitre ,  Gene A. Bornzin ,  John R. Helland ,  Eric Falkenberg ,  Kevin L. Morgan ,  Sheldon Williams ,  Michael Yang ,  Andrew W. McGarvey

IPC分类号： A61N1/00

CPC分类号： A61F2/2478 ,  A61B17/00 ,  A61B17/0057 ,  A61N1/0587

摘要： A chamber or vasculature of a heart may be accessed via the pericardial space of the heart. Initially, the pericardial space may be accessed via a transmyocardial approach or a subxiphoid approach. A lead or other implantable apparatus may thus be routed into the pericardial space, through myocardial tissue and into the chamber or vasculature. The lead or other apparatus may be used to sense activity in or provide therapy to the heart.

摘要翻译： 可以通过心脏的心包空间访问心脏的腔室或脉管系统。 最初，心包空间可以通过心肌的方法或亚型的方法进行。 因此，引线或其它可植入装置可通过心肌组织进入心包空间并进入腔室或脉管系统。 铅或其他装置可用于感测心脏的活动或提供对心脏的治疗。

公开(公告)号：US08311648B1

公开(公告)日：2012-11-13

申请号：US12973800

申请日：2010-12-20

申请人： Yougandh Chitre ,  Gene A. Bornzin ,  John R. Helland ,  Eric Falkenberg ,  Kevin L. Morgan ,  Sheldon Williams ,  Michael Yang ,  Andrew W. McGarvey

发明人： Yougandh Chitre ,  Gene A. Bornzin ,  John R. Helland ,  Eric Falkenberg ,  Kevin L. Morgan ,  Sheldon Williams ,  Michael Yang ,  Andrew W. McGarvey

IPC分类号： A61N1/05

CPC分类号： A61F2/2478 ,  A61B17/00 ,  A61B17/0057 ,  A61N1/0587

摘要： A delivery apparatus for accessing the pericardial space of a heart including an elongated body defining a lumen and a piercing member that extends from a distal portion of the elongated body for piercing tissue of the heart. A spring expands from a distal end of the piercing member in response to the distal end of the piercing member passing through the tissue and into the pericardial space. An electrode located on the spring in order to sense signals indicative of a distal end of the spring passing through the tissue and into the pericardial space.

摘要翻译： 一种用于进入心脏的心包空间的输送装置，包括限定内腔的细长主体和从细长主体的远端部分延伸以刺穿心脏的组织的穿刺构件。 响应于刺穿构件的远端穿过组织并进入心包空间，弹簧从穿刺构件的远端膨胀。 位于弹簧上的电极，用于感测指示穿过组织并进入心包空间的弹簧的远端的信号。

公开(公告)号：US07319905B1

公开(公告)日：2008-01-15

申请号：US11121881

申请日：2005-05-03

申请人： Kevin L. Morgan ,  Michael Yang ,  Sheldon Williams ,  Andrew W. McGarvey

发明人： Kevin L. Morgan ,  Michael Yang ,  Sheldon Williams ,  Andrew W. McGarvey

IPC分类号： A61N1/05

CPC分类号： A61N1/0587

摘要： An implantable lead having an elongated lead body that includes an electrical conductor extending between a distal end of the lead body and a proximal end of the lead body is disclosed. The lead further includes an electrode formed at the distal end of the lead body, the electrode being coupled to the electrical conductor and one or more passive fixation mesh sections coupled to the distal end of the lead body that promotes tissue over growth.

公开(公告)号：US07881810B1

公开(公告)日：2011-02-01

申请号：US11753484

申请日：2007-05-24

申请人： Yougandh Chitre ,  Gene A. Bornzin ,  John R. Helland ,  Eric Falkenberg ,  Kevin L. Morgan ,  Sheldon Williams ,  Michael Yang ,  Andrew W. McGarvey

发明人： Yougandh Chitre ,  Gene A. Bornzin ,  John R. Helland ,  Eric Falkenberg ,  Kevin L. Morgan ,  Sheldon Williams ,  Michael Yang ,  Andrew W. McGarvey

IPC分类号： A61N1/05

CPC分类号： A61F2/2478 ,  A61B17/00 ,  A61B17/0057 ,  A61N1/0587

摘要： A chamber or vasculature of a heart may be accessed via the pericardial space of the heart. Initially, the pericardial space may be accessed via a transmyocardial approach or a subxiphoid approach. A lead or other implantable apparatus may thus be routed into the pericardial space, through myocardial tissue and into the chamber or vasculature. The lead or other apparatus may be used to sense activity in or provide therapy to the heart.

摘要翻译： 可以通过心脏的心包空间访问心脏的腔室或脉管系统。 最初，心包空间可以通过心肌的方法或亚型的方法进行。 因此，引线或其它可植入装置可通过心肌组织进入心包空间并进入腔室或脉管系统。 铅或其他装置可用于感测心脏的活动或提供对心脏的治疗。

公开(公告)号：US20130261687A1

公开(公告)日：2013-10-03

申请号：US13436578

申请日：2012-03-30

申请人： Cecilia Qin Xi ,  Diana Gavales ,  Andrew Miller ,  Andrew W. McGarvey ,  Zachary Briggs ,  David Bishop ,  Sharon Standage ,  Anil Keni ,  Richard Block ,  Heidi Hellman ,  Taryn Smith

发明人： Cecilia Qin Xi ,  Diana Gavales ,  Andrew Miller ,  Andrew W. McGarvey ,  Zachary Briggs ,  David Bishop ,  Sharon Standage ,  Anil Keni ,  Richard Block ,  Heidi Hellman ,  Taryn Smith

IPC分类号： A61N1/368

CPC分类号： A61N1/3686

摘要： Techniques are provided for use with an implantable cardiac stimulation device equipped with a multi-pole left ventricular (LV) lead and a right ventricular (RV) lead for identifying suitable pacing vectors. In one example, RV-LV delay times are measured while using different electrodes of the LV lead as cathodes for sensing. The LV electrode having the longest RV-LV delay time is identified and LV capture thresholds and diaphragmatic stimulation thresholds are measured for pacing vectors that employ that LV electrode as a cathode. Assuming at least one vector employing the selected LV electrode is found to have acceptable thresholds, the vector is selected for use in delivering pacing therapy with the selected LV electrode. If none of the pacing vectors employing the selected LV electrode has acceptable thresholds, another LV electrode is selected and the procedure is repeated. Examples with a multi-pole RV lead are also described.

摘要翻译： 技术提供用于配备有多极左心室（LV）引线和右心室（RV）引线的可植入心脏刺激装置，用于识别合适的起搏向量。 在一个示例中，测量RV-LV延迟时间，同时使用LV引线的不同电极作为用于感测的阴极。 识别具有最长RV-LV延迟时间的LV电极，并测量采用该LV电极作为阴极的起搏向量的LV捕获阈值和膈肌刺激阈值。 假设使用所选择的LV电极的至少一个载体被发现具有可接受的阈值，则选择该载体用于与选定的LV电极递送起搏治疗。 如果没有采用所选择的LV电极的起搏向导具有可接受的阈值，则选择另一LV电极并重复该过程。 还描述了具有多极RV引线的示例。

公开(公告)号：US09610447B2

公开(公告)日：2017-04-04

申请号：US13436578

申请日：2012-03-30

申请人： Cecilia Qin Xi ,  Diana Gavales ,  Andrew Miller ,  Andrew W. McGarvey ,  Zachary Briggs ,  David Bishop ,  Sharon Standage ,  Anil Keni ,  Richard Block ,  Heidi Hellman ,  Taryn Smith

发明人： Cecilia Qin Xi ,  Diana Gavales ,  Andrew Miller ,  Andrew W. McGarvey ,  Zachary Briggs ,  David Bishop ,  Sharon Standage ,  Anil Keni ,  Richard Block ,  Heidi Hellman ,  Taryn Smith

IPC分类号： A61N1/36 ,  A61N1/368

CPC分类号： A61N1/3686

摘要： Techniques are provided for use with an implantable cardiac stimulation device equipped with a multi-pole left ventricular (LV) lead and a right ventricular (RV) lead for identifying suitable pacing vectors. In one example, RV-LV delay times are measured while using different electrodes of the LV lead as cathodes for sensing. The LV electrode having the longest RV-LV delay time is identified and LV capture thresholds and diaphragmatic stimulation thresholds are measured for pacing vectors that employ that LV electrode as a cathode. Assuming at least one vector employing the selected LV electrode is found to have acceptable thresholds, the vector is selected for use in delivering pacing therapy with the selected LV electrode. If none of the pacing vectors employing the selected LV electrode has acceptable thresholds, another LV electrode is selected and the procedure is repeated. Examples with a multi-pole RV lead are also described.