公开(公告)号：US20240102900A1

公开(公告)日：2024-03-28

申请号：US18530661

申请日：2023-12-06

Applicant: Shenzhen Huixin Life Technologies Co., Ltd.

Inventor： YUCHAO CHEN

IPC: G01N1/34 ,  G01N1/40

CPC classification number: G01N1/34 ,  G01N1/4005 ,  G01N2001/4016

Abstract: An isolation device for isolation of target particles from a plurality of liquid samples includes a plurality of isolation chips and a vacuum system. Each of the plurality of isolation chips includes a sample reservoir, and a first outlet and a second outlet disposed at opposite sides of the sample reservoir. The vacuum system includes a first vacuum pump connected to the first outlet of each of the plurality of isolation chips and a second vacuum pump connected to the second outlet of each of the plurality of isolation chips. The first vacuum pump generates a negative pressure in each of the plurality of isolation chips through a corresponding first outlet. The second vacuum pump generates a negative pressure in each of the plurality of isolation chips through a corresponding second outlet. The target particles are isolated from each of the plurality of liquid samples in a corresponding sample reservoir.

公开(公告)号：US20240151614A1

公开(公告)日：2024-05-09

申请号：US17774914

申请日：2022-01-28

Applicant: Shenzhen Huixin Life Technologies Co., Ltd

Inventor： YIJIE YANG ,  YUCHAO CHEN

IPC: G01N1/40 ,  B01D65/08

CPC classification number: G01N1/4077 ,  B01D65/08 ,  B01D2321/2058 ,  B01D2321/35 ,  G01N2001/4088 ,  G01N2001/4094

Abstract: An isolation device includes an isolation chip, a pressing assembly, two ultrasonic generators, a differential pressure driving system, a frequency conversion module, and a controller. The isolation chip includes a sample reservoir, a first chamber, and a second chamber. The pressing assembly drives the two ultrasonic generators to move towards the isolation chip to make in contact with the first and second chambers. The frequency conversion module controls the differential pressure driving system to generate a negative pressure in the first and second chambers alternately. The controller controls the two ultrasonic generators to generate two ultrasonic waves when negative pressures are cancelled in the first and second chambers. An isolation method is also disclosed.

公开(公告)号：US20230160795A1

公开(公告)日：2023-05-25

申请号：US17767594

申请日：2020-11-11

Applicant: SHENZHEN HUIXIN LIFE TECHNOLOGIES CO., LTD

Inventor： YUCHAO CHEN

IPC: G01N1/34 ,  C12M1/26

CPC classification number: G01N1/34 ,  C12M33/14 ,  G01N2001/4088

Abstract: An isolation chip assembly includes an isolation chip (10), first oscillators (20), and second oscillators (30). The isolation chip (10) includes a sample reservoir (13), a first filtration membrane (14) and a second filtration membrane (16) at opposite sides of the sample reservoir (13) . The first oscillators (20) are mounted on the first filtration membrane (14) and the second filtration membrane (16), and can generate a first oscillation wave when operating. The second oscillators (30) are mounted on outer surfaces of the first chamber (15) and the second chamber (17), and can generate a second oscillation wave when operating. A frequency of the first oscillation wave is greater than a frequency of the second oscillation wave, and an amplitude of the first oscillation wave is less than an amplitude of the second oscillation wave.

公开(公告)号：US20220136938A1

公开(公告)日：2022-05-05

申请号：US17576654

申请日：2022-01-14

Applicant: Shenzhen Huixin Life Technologies Co., Ltd

Inventor： YUCHAO CHEN

IPC: G01N1/34 ,  G01N1/40

Abstract: An isolation device for isolation of target particles from a plurality of liquid samples includes a plurality of isolation chips and a vacuum system. Each of the plurality of isolation chips includes a sample reservoir, and a first outlet and a second outlet disposed at opposite sides of the sample reservoir. The vacuum system includes a first vacuum pump connected to the first outlet of each of the plurality of isolation chips and a second vacuum pump connected to the second outlet of each of the plurality of isolation chips. The first vacuum pump generates a negative pressure in each of the plurality of isolation chips through a corresponding first outlet. The second vacuum pump generates a negative pressure in each of the plurality of isolation chips through a corresponding second outlet. The target particles are isolated from each of the plurality of liquid samples in a corresponding sample reservoir.