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公开(公告)号：US20150044691A1
公开(公告)日：2015-02-12
申请号：US14523658
申请日：2014-10-24
发明人： Eiichi Matsuo , Naoki Kaneko , Makoto Watanabe , Osamu Nishimura , Noboru Okamura , Akinobu Gotoh
IPC分类号： G01N33/574
CPC分类号： G01N33/57438 , C12N9/96 , G01N33/6893 , G01N2333/4724 , G01N2333/988
摘要： The present invention provides a blood marker for renal cancer, more specifically, a blood marker that can be practically used for clinical diagnosis of renal cancer. The present invention also provides a blood marker that can be practically used for follow-up after treatment such as surgery and during treatment such as medication for renal cancer. A blood marker for renal cancer selected from the group consisting of Galectin-1, Galectin-3, and α-enolase. Galectin-1 and/or Galectin-3 as a blood marker for renal cancer for use in an examination performed before diagnostic imaging. α-Enolase as a blood marker for renal cancer for use in monitoring during and/or after treatment for renal cancer.
摘要翻译： 本发明提供了用于肾癌的血液标志物，更具体地，可以实际用于肾癌的临床诊断的血液标志物。 本发明还提供了一种血液标志物，其可以实际用于治疗之后的后续，例如手术和治疗期间，例如用于肾癌的药物。 选自Galectin-1，Galectin-3和α-烯醇化酶的肾癌血液标志物。 Galectin-1和/或Galectin-3作为肾癌的血液标志物，用于在诊断成像之前进行的检查。 α-烯醇化酶作为用于肾癌治疗期间和/或治疗期间的肾癌的血液标志物。
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公开(公告)号：US20130171660A1
公开(公告)日：2013-07-04
申请号：US13728932
申请日：2012-12-27
发明人： Eiichi Matsuo , Naoki Kaneko , Makoto Watanabe , Osamu Nishimura , Noboru Okamura , Akinobu Gotoh
CPC分类号： G01N33/57438 , C12N9/96 , G01N33/6893 , G01N2333/4724 , G01N2333/988
摘要： The present invention provides a blood marker for renal cancer, more specifically, a blood marker that can be practically used for clinical diagnosis of renal cancer. The present invention also provides a blood marker that can be practically used for follow-up after treatment such as surgery and during treatment such as medication for renal cancer. A blood marker for renal cancer selected from the group consisting of Galectin-1, Galectin-3, and α-enolase. Galectin-1 and/or Galectin-3 as a blood marker for renal cancer for use in an examination performed before diagnostic imaging. α-Enolase as a blood marker for renal cancer for use in monitoring during and/or after treatment for renal cancer.
摘要翻译： 本发明提供了用于肾癌的血液标志物，更具体地，可以实际用于肾癌的临床诊断的血液标志物。 本发明还提供了一种血液标志物，其可以实际用于治疗之后的后续，例如手术和治疗期间，例如用于肾癌的药物。 选自Galectin-1，Galectin-3和α-烯醇化酶的肾癌的血液标志物。 Galectin-1和/或Galectin-3作为肾癌的血液标志物，用于在诊断成像之前进行的检查。 α-烯醇化酶作为用于肾癌治疗期间和/或之后的监测用于肾癌的血液标志物。
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公开(公告)号：US20200098553A1
公开(公告)日：2020-03-26
申请号：US16576902
申请日：2019-09-20
申请人： Shimadzu Corporation
发明人： Takushi Yamamoto , Eiichi Matsuo
摘要： An analyzing device includes: a measurement data acquisition unit that acquires measurement data obtained by irradiating a plurality of irradiation positions on a sample with a laser beam and performing mass spectrometry on a sample component corresponding to each irradiation position; and an analysis unit that performs analysis of the measurement data by excluding a set of data corresponding to an excluded irradiation position among the plurality of irradiation positions each having a different irradiation portion from which a portion that has been already irradiated with the laser beam is excluded in an irradiation range irradiated when the laser beam is irradiated to each irradiation position.
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公开(公告)号：US20160003830A1
公开(公告)日：2016-01-07
申请号：US14852308
申请日：2015-09-11
发明人： Makoto Watanabe , Eiichi Matsuo , Naoki Kaneko , Toshiya Matsubara , Osamu Nishimura , Masaki Mori , Hideo Matsuda , Shigeto Seno , Ichiro Takemasa
IPC分类号： G01N33/574
CPC分类号： G01N33/57419 , G01N33/6893
摘要： The present invention provides a specific combination of colon cancer markers based on statistical knowledge, which is capable of detecting a larger number of colon cancer patients in an earlier stage while maintaining high specificity. A multiplex colon cancer marker panel comprising a combination of five colon cancer markers of Carcinoembryonic antigen-related cell adhesion molecule 5, Carbohydrate antigen 19-9, Galectin-4, APEX nuclease and Actin-related protein 2. A method for analyzing colon cancer markers using multiplex colon cancer marker panel.
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公开(公告)号：US11024493B2
公开(公告)日：2021-06-01
申请号：US16576902
申请日：2019-09-20
申请人： SHIMADZU CORPORATION
发明人： Takushi Yamamoto , Eiichi Matsuo
摘要： An analyzing device includes: a measurement data acquisition unit that acquires measurement data obtained by irradiating a plurality of irradiation positions on a sample with a laser beam and performing mass spectrometry on a sample component corresponding to each irradiation position; and an analysis unit that performs analysis of the measurement data by excluding a set of data corresponding to an excluded irradiation position among the plurality of irradiation positions each having a different irradiation portion from which a portion that has been already irradiated with the laser beam is excluded in an irradiation range irradiated when the laser beam is irradiated to each irradiation position.
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公开(公告)号：US10809262B2
公开(公告)日：2020-10-20
申请号：US14852308
申请日：2015-09-11
发明人： Makoto Watanabe , Eiichi Matsuo , Naoki Kaneko , Toshiya Matsubara , Osamu Nishimura , Masaki Mori , Hideo Matsuda , Shigeto Seno , Ichiro Takemasa
IPC分类号： G01N33/574 , G01N33/68
摘要： The present invention provides a specific combination of colon cancer markers based on statistical knowledge, which is capable of detecting a larger number of colon cancer patients in an earlier stage while maintaining high specificity. A multiplex colon cancer marker panel comprising a combination of five colon cancer markers of Carcinoembryonic antigen-related cell adhesion molecule 5, Carbohydrate antigen 19-9, Galectin-4, APEX nuclease and Actin-related protein 2. A method for analyzing colon cancer markers using multiplex colon cancer marker panel.
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公开(公告)号：US20130165340A1
公开(公告)日：2013-06-27
申请号：US13723133
申请日：2012-12-20
发明人： Makoto Watanabe , Eiichi Matsuo , Naoki Kaneko , Toshiya Matsubara , Osamu Nishimura , Masaki Mori , Hideo Matsuda , Shigeto Seno , Ichiro Takemasa
IPC分类号： G01N33/68
CPC分类号： G01N33/57419 , G01N33/6893
摘要： The present invention provides a specific combination of colon cancer markers based on statistical knowledge, which is capable of detecting a larger number of colon cancer patients in an earlier stage while maintaining high specificity. A multiplex colon cancer marker panel comprising a combination of five colon cancer markers of Carcinoembryonic antigen-related cell adhesion molecule 5, Carbohydrate antigen 19-9, Galectin-4, APEX nuclease and Actin-related protein 2.A method for analyzing colon cancer markers using multiplex colon cancer marker panel.
摘要翻译： 本发明提供了基于统计知识的结肠癌标志物的特异性组合，其能够在保持高特异性的同时检测较早数量的结肠癌患者。 包括癌胚抗原相关细胞粘附分子5，碳水化合物抗原19-9，半乳凝素-4，APEX核酸酶和肌动蛋白相关蛋白2的五个结肠癌标志物的组合的多重结肠癌标志物。2.一种分析结肠癌标志物的方法 使用多重结肠癌标记物。
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