摘要:
The invention relates to compounds of the following formula (I) or their salts: in which R1 is a group of phenyl, naphthyl, pyridyl or the like which may have a substituent such as an alkyl group having 1-8 carbon atoms, an alkoxy group having 1-8 carbon atoms, an alkoxycarbonyl group having 2-8 carbon atoms, carboxyl, halogen, hydroxyl, nitro, or cyano; R2 is cyano, nitro, or the like; R3 is hydroxyl or the like; X is oxygen, sulfur, or the like; and Y is oxygen or sulfur, and a xanthine oxidase inhibitor containing the compound.
摘要:
The invention relates to compounds of the following formula (I) or their salts: in which R1 is a group of phenyl, naphthyl, pyridyl or the like which may have a substituent such as an alkyl group having 1-8 carbon atoms, an alkoxy group having 1-8 carbon atoms, an alkoxycarbonyl group having 2-8 carbon atoms, carboxyl, halogen, hydroxyl, nitro, or cyano; R2 is cyano, nitro, or the like; R3 is hydroxyl or the like; X is oxygen, sulfur, or the like; and Y is oxygen or sulfur, and a xanthine oxidase inhibitor containing the compound.
摘要翻译:本发明涉及下式(I)化合物或其盐:其中R 1是苯基,萘基,吡啶基等可以具有取代基的基团,例如具有 1-8个碳原子,具有1-8个碳原子的烷氧基,具有2-8个碳原子的烷氧基羰基,羧基,卤素,羟基,硝基或氰基; R 2是氰基,硝基等; R 3是羟基等; X是氧,硫等; Y为氧或硫,含有该化合物的黄嘌呤氧化酶抑制剂。
摘要:
The invention relates to compounds of the following formula (I) or their salts: in which R1 represents OR4 or others, in which R4 is an alkyl group having 1-8 carbon atoms which may have a substituent or the like; R2 is halogen, nitro, cyano, carboxyl, or the like; R3 is hydrogen, halogen, hydroxyl, amino, carboxyl, or the like; X is NR11, oxygen, or sulfur, in which R11 is hydrogen, or an alkyl group having 1-8 carbon atom which may have a substituent; and each of Y and Z is CR12 or nitrogen, in which R12 has the same meaning as R3 above, and a xanthine oxidase inhibitor containing the compound as an active ingredient.
摘要翻译:本发明涉及下式(I)的化合物或其盐:其中R 1表示OR 4或其它,其中R 4 O / >是具有1-8个碳原子的可以具有取代基等的烷基; R 2是卤素,硝基,氰基,羧基等; R 3是氢,卤素,羟基,氨基,羧基等; X是NR 11,其中R 11是氢的氧或硫,或可以具有取代基的具有1-8个碳原子的烷基; Y和Z各自为CR 12或氮,其中R 12具有与上述R 3相同的含义,并且黄嘌呤氧化酶 含有该化合物作为活性成分的抑制剂。
摘要:
The invention relates to compounds of the following formula (I) or their salts: in which R1 represents OR4 or others, in which R4 is an alkyl group having 1-8 carbon atoms which may have a substituent or the like; R2 is halogen, nitro, cyano, carboxyl, or the like; R3 is hydrogen, halogen, hydroxyl, amino, carboxyl, or the like; X is NR11, oxygen, or sulfur, in which R11 is hydrogen, or an alkyl group having 1-8 carbon atom which may have a substituent; and each of Y and Z is CR12 or nitrogen, in which R12 has the same meaning as R3 above, and a xanthine oxidase inhibitor containing the compound as an active ingredient.
摘要翻译:本发明涉及下式(I)的化合物或其盐:其中R 1表示OR 4或其它,其中R 4 O / >是具有1-8个碳原子的可以具有取代基等的烷基; R 2是卤素,硝基,氰基,羧基等; R 3是氢,卤素,羟基,氨基,羧基等; X是NR 11,其中R 11是氢的氧或硫,或可以具有取代基的具有1-8个碳原子的烷基; Y和Z各自为CR 12或氮,其中R 12具有与上述R 3相同的含义,并且黄嘌呤氧化酶 含有该化合物作为活性成分的抑制剂。
摘要:
The invention relates to compounds of the following formula (I) or their salts: in which R1 represents OR4 or others, in which R4 is an alkyl group having 1-8 carbon atoms which may have a substituent or the like; R2 is halogen, nitro, cyano, carboxyl, or the like; R3 is hydrogen, halogen, hydroxyl, amino, carboxyl, or the like; X is NR11, oxygen, or sulfur, in which R11 is hydrogen, or an alkyl group having 1-8 carbon atom which may have a substituent; and each of Y and Z is CR12 or nitrogen, in which R12 has the same meaning as R3 above, and a xanthine oxidase inhibitor containing the compound as an active ingredient.
摘要翻译:本发明涉及下式(I)的化合物或其盐:其中R 1表示OR 4或其它,其中R 4 O / >是具有1-8个碳原子的可以具有取代基等的烷基; R 2是卤素,硝基,氰基,羧基等; R 3是氢,卤素,羟基,氨基,羧基等; X是NR 11,其中R 11是氢的氧或硫,或可以具有取代基的具有1-8个碳原子的烷基; Y和Z各自为CR 12或氮,其中R 12具有与上述R 3相同的含义,并且黄嘌呤氧化酶 含有该化合物作为活性成分的抑制剂。
摘要:
A compound represented by the following formula (I) is used as a xanthine oxidase inhibitor: in which R1 is phenyl or pyridyl each optionally having, as a substituent, C1-8 alkyl, C1-8 haloalkyl, C1-8 alkoxy, carboxyl, halogeno, hydroxyl, nitro, cyano, amino, etc.; R2 is cyano, nitro, etc.; X is oxygen, sulfur, etc.; and Y is sulfur, NH, etc.