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8 条记录 (耗时 0.032 秒)

    Meltrins
    6.
    发明授权
    Meltrins 失效

    公开(公告)号：US07060791B2

    公开(公告)日：2006-06-13

    申请号：US09983531

    申请日：2001-10-24

    申请人： Atsuko Fujisawa ,  Toru Yamakawa ,  Kamon Shirakawa ,  Chitose Orii ,  Naoki Ogawa

    发明人： Atsuko Fujisawa ,  Toru Yamakawa ,  Kamon Shirakawa ,  Chitose Orii ,  Naoki Ogawa

    IPC分类号： A61K38/04

    CPC分类号： C12N9/6489 ,  A61K38/00 ,  A61K2039/505 ,  C07K14/705 ,  C07K16/40 ,  C07K2317/76

    摘要： The purpose of the present invention is to provide a novel protein involved in adhesion and fusion between myoblasts in the course of the formation of byotube. The present invention relates to Meltrins, which a membrane protein having fusion, adhesion and aggregation activity of cells, especially myoblast; and to polypeptides of their domains, DNAs encoding them, antisense RNA for these DNAs, various antibodies to Meltrins and the polypeptides of their domains, expression vectors containing these DNAs, and transformants by these vectors; as well as to the process for producing Meltrins and the polypeptides of their domains using those transformants and medical compositions comprising Meltrins or antagonist against them as an effective ingredient.

    MELTRINS
    8.
    发明申请
    MELTRINS 失效
    墨西哥

    公开(公告)号：US20060247164A1

    公开(公告)日：2006-11-02

    申请号：US11276738

    申请日：2006-03-13

    申请人： Atsuko Fujisawa ,  Toru Yamakawa ,  Kamon Shirakawa ,  Chitose Orii ,  Naoki Ogawa

    发明人： Atsuko Fujisawa ,  Toru Yamakawa ,  Kamon Shirakawa ,  Chitose Orii ,  Naoki Ogawa

    IPC分类号： A61K38/17 ,  C07K14/705 ,  C07K16/18

    CPC分类号： C12N9/6489 ,  A61K38/00 ,  A61K2039/505 ,  C07K14/705 ,  C07K16/40 ,  C07K2317/76

    摘要： The purpose of the present invention is to provide a novel protein involved in adhesion and fusion between myoblasts in the course of the formation of byotube. The present invention relates to Meltrins, which a membrane protein having fusion, adhesion and aggregation activity of cells, especially myoblast; and to polypeptides of their domains, DNAs encoding them, antisense RNA for these DNAs, various antibodies to Meltrins and the polypeptides of their domains, expression vectors containing these DNAs, and transformants by these vectors; as well as to the process for producing Meltrins and the polypeptides of their domains using those transformants and medical compositions comprising Meltrins or antagonist against them as an effective ingredient.

    摘要翻译： 本发明的目的是提供一种新颖的蛋白质，其涉及在成骨细胞形成过程中成肌细胞之间的粘附和融合。 本发明涉及一种蛋白质，其具有细胞，特别是成肌细胞的融合，粘附和聚集活性的膜蛋白; 和其结构域的多肽，编码它们的DNA，这些DNA的反义RNA，对于Meltrins的各种抗体及其结构域的多肽，含有这些DNA的表达载体和通过这些载体的转化体; 以及使用这些转化体和包含Meltrins或其拮抗剂的药物组合物作为有效成分来生产Meltrins及其结构域的多肽的方法。