-
公开(公告)号：US09540301B2
公开(公告)日：2017-01-10
申请号：US14113498
申请日：2012-04-26
IPC分类号： C07C51/09 , C07F9/40 , C07C57/03 , A61K31/167 , A61K31/202 , A61K33/16 , A61K35/742 , A61K35/744 , A61K45/06 , C07C67/343 , C07C51/353 , A61K9/48
CPC分类号： C07C51/09 , A61K9/4858 , A61K9/4866 , A61K9/4875 , A61K31/167 , A61K31/202 , A61K33/16 , A61K35/742 , A61K35/744 , A61K45/06 , C07C51/353 , C07C57/03 , C07C67/343 , C07F9/4015 , A61K2300/00 , C07C69/587
摘要： Provided is a method of manufacturing a high quality phosphonocrotonic acid derivative.The present invention is a method of manufacturing a compound represented by the following Formula (3) by reacting a compound represented by the following Formula (1) with a compound represented by the following Formula (2), which comprises a treatment process using an acid or base.[in the formula, R1 represents a C1-6 linear or branched alkyl group that may be substituted by a C6-10 aryl group, a C2-6 linear or branched alkenyl group that may be substituted by a C6-10 aryl group, a C2-6 linear or branched alkynyl group that may be substituted by a C6-10 aryl group, or a C6-10 aryl group, R2 represents a hydrogen atom, or a C1-6 linear or branched alkyl group that may be substituted by a C6-10 aryl group, R3 represents a C1-6 linear or branched alkyl group, a C6-10 aryl group, or a halogen atom, and X represents a halogen atom, and multiple R1s may be the same or different].
摘要翻译： 提供制造高品质膦酸巴豆酸衍生物的方法。 本发明是通过使由下式（1）表示的化合物与下式（2）表示的化合物反应来制备由下式（3）表示的化合物的方法，该方法包括使用酸 或基地。 [式中，R 1表示可以被C 6-10芳基取代的C 1-6直链或支链烷基，可以被C 6-10芳基取代的C 2-6直链或支链烯基， 10芳基，可以被C 6-10芳基取代的C 2-6直链或支链炔基或C 6-10芳基，R 2表示氢原子或C 1-6直链 或可被C 6-10芳基取代的支链烷基，R 3表示C 1-6直链或支链烷基，C 6-10芳基或卤素原子，X表示卤素原子 ，多个R 1可以相同或不同]。
-
公开(公告)号：US20140051876A1
公开(公告)日：2014-02-20
申请号：US14113498
申请日：2012-04-26
CPC分类号： C07C51/09 , A61K9/4858 , A61K9/4866 , A61K9/4875 , A61K31/167 , A61K31/202 , A61K33/16 , A61K35/742 , A61K35/744 , A61K45/06 , C07C51/353 , C07C57/03 , C07C67/343 , C07F9/4015 , A61K2300/00 , C07C69/587
摘要： Provided is a method of manufacturing a high quality phosphonocrotonic acid derivative.The present invention is a method of manufacturing a compound represented by the following Formula (3) by reacting a compound represented by the following Formula (1) with a compound represented by the following Formula (2), which comprises a treatment process using an acid or base.[in the formula, R1 represents a C1-6 linear or branched alkyl group that may be substituted by a C6-10 aryl group, a C2-6 linear or branched alkenyl group that may be substituted by a C6-10 aryl group, a C2-6 linear or branched alkynyl group that may be substituted by a C6-10 aryl group, or a C6-10 aryl group, R2 represents a hydrogen atom, or a C1-6 linear or branched alkyl group that may be substituted by a C6-10 aryl group, R3 represents a C1-6 linear or branched alkyl group, a C6-10 aryl group, or a halogen atom, and X represents a halogen atom, and multiple R1s may be the same or different].
摘要翻译： 提供制造高品质膦酸巴豆酸衍生物的方法。 本发明是通过使由下式（1）表示的化合物与下式（2）表示的化合物反应来制备由下式（3）表示的化合物的方法，该方法包括使用酸 或基地。 [式中，R 1表示可被C 6-10芳基取代的C 1-6直链或支链烷基，可被C 6-10芳基取代的C 2-6直链或支链烯基， 可被C 6-10芳基或C 6-10芳基取代的C 2-6直链或支链炔基，R 2表示氢原子，或可被C 1-6烷基取代的C 1-6直链或支链烷基 C6-10芳基，R3表示C1-6直链或支链烷基，C6-10芳基或卤素原子，X表示卤素原子，多个R1可以相同或不同]。
-
公开(公告)号：US20080142424A1
公开(公告)日：2008-06-19
申请号：US10597627
申请日：2005-01-28
申请人： Hiroshi Kitasako , Masao Katsube , Katsuhiro Sakamoto , Junzo Sago , Hiroaki Tanaka , Jun Tsumori
发明人： Hiroshi Kitasako , Masao Katsube , Katsuhiro Sakamoto , Junzo Sago , Hiroaki Tanaka , Jun Tsumori
IPC分类号： C02F3/20
CPC分类号： B01F5/0268 , B01F1/0022 , B01F3/0446 , B01F2003/04879 , B01F2215/0052
摘要： A gas-liquid dissolving apparatus that dissolves an oxygen-containing gas into water taken in from an oxygen-deficient water area, increases a dissolved oxygen concentration of the water, and returns the increased dissolved oxygen concentration water to the oxygen-deficient water area is provided. The apparatus includes a pump 3 that takes in the water from the oxygen-deficient water area, an oxygen supplying unit 4 that supplies the oxygen-containing gas, an elongated cylindrical gas-liquid dissolving chamber 5 that has at least one hole 5b formed in a lower portion and that has a dome-shaped top plate 5a provided in an upper portion, a nozzle 2 that ejects the gas from the oxygen supplying unit 4 and the water from the pump 3 upward so that the gas and the water strike against an inner wall of the top plate 5a of the gas-liquid dissolving chamber 5, that vigorously agitates the gas and the water by forces of the ejected gas and water, and that has a tip end having a tapered inside, a gas-liquid separating chamber 6 that communicates with the gas-liquid dissolving chamber 5 through the hole 5b, and that separates bubbles and the water flowing out from the gas-liquid dissolving chamber 5 through the hole 5b from each other while storing the bubbles and the water, and a water supply port 6b that returns the water separated from the bubbles to the oxygen-deficient water area.
摘要翻译： 将含氧气体从缺氧水区域吸入水中的气液溶解装置增加溶解氧的浓度，使氧浓度不足的水回流到氧缺水区域 提供。 该装置包括从缺氧水区域吸入水的泵3，供给含氧气体的供氧单元4，形成有至少一个孔5b的细长圆柱形气液溶解室5 在下部具有设置在上部的圆顶状的顶板5a，将来自氧供给单元4的气体和来自泵3的水向上方喷射的喷嘴2，使得气体和水的冲击 靠着气液溶解室5的顶板5a的内壁，由于排出的气体和水的力而剧烈地搅动气体和水，并且具有锥形内侧的顶端， 液体分离室6，其通过孔5b与气液溶解室5连通，并且通过孔5b将气泡和从气液溶解室5流出的水分离，同时储存气泡， 水和一个wat 呃供给端口6b将从气泡分离的水返回到缺水区域。
-
公开(公告)号：US20050159688A1
公开(公告)日：2005-07-21
申请号：US10504187
申请日：2003-02-10
IPC分类号： A61H15/00
CPC分类号： A61H15/0092 , A61H2015/0014 , A61H2205/10
摘要： This invention relates to a massager and a massing method. There has been known a conventional leg massager described in Japanese Utility Model Registration No. 3043777. However, there are great differences between individuals in their configurations of the legs, i.e. the above-knee and below-knee parts. Specifically, the shape of the leg portion from ankle to calf of leg differs greatly in individuals, the conventional massager has suffered a disadvantage such that it is difficult to massage the whole leg sufficiently with a single roller and the work becomes onerous where changing the roller in accordance with the shape of the leg. In the light of the foregoing disadvantages of the conventional massager, the present invention was made to provide a massager comprising stays connecting a plurality of rollers, and operating parts extending longitudinally from the stays. With the massager, a massage can be applied to the arm or leg of a user by handling the operating parts extending so as to incline the stays for adjusting the inclination of the stays, consequently to allow the rollers to conform to the shape of the arm or leg and exert massaging pressure on the arm or leg while rotating the rollers along the arm or leg without weakening the massaging pressure. Thus, the massage can be given to the entire aim and leg of the user in an unrestrained operation without restricting the posture of the user being massaged with the massager. In order to solve all of the conventional problems imposed by the conventional massagers, according to the present invention there is provided a massager comprising stays, operating parts formed on the stays, and roller means comprising a plurality of rollers, which are rotatably supported by the stays for holding an arm or leg between the rollers and adjustable in distance therebetween by handling the operating parts to change the inclination of the stays. That is, smooth rolling pressure can readily be given to the arm or leg by handling the operating parts to allow the rollers to conform to the configuration of the arm or leg and rotating the rollers along the arm or leg held between the rollers, while varying the inclination of the stays to adjust the distance between the rollers.
-
公开(公告)号：US07389807B2
公开(公告)日：2008-06-24
申请号：US10528574
申请日：2004-06-30
申请人： Toyohide Nagare , Hideki Tanemura , Atsushi Matsumura , Masahito Goto , Takashi Nagata , Katsuhiro Sakamoto
发明人： Toyohide Nagare , Hideki Tanemura , Atsushi Matsumura , Masahito Goto , Takashi Nagata , Katsuhiro Sakamoto
IPC分类号： A47G5/02
CPC分类号： E06B9/581 , E06B9/13 , E06B2009/585
摘要： When a fitting piece slips out of a rail groove of a guide rail in connection with an excessive load on a shutter curtain is restored to the rail groove, the restoration is reliably set and noiselessly carried out. A posture holding bar and fitting pieces, which are spaced from both right and left sides of the posture holding bar at a predetermined interval, are provided at the lower end portion of the shutter curtain. A first guide body guides the posture holding bar to the opposing site to the rail groove in the process of an opening/closing operation of the shutter curtain. A second guide body guides the fitting piece at the lower end portion of the shutter curtain to the opposing side to the rail groove in conformity with a timing at which the posture holding bar is positionally regulated to the opposing side to the rail groove by the first guide body is provided at the upper side of the rail groove constituting the guide rail.
摘要翻译： 当与挡板上的过大负载相关联的导轨的轨道槽中滑动的装配件被还原到轨道槽时，恢复被可靠地设定并且无噪声地进行。 在闸门帘幕的下端部设置有以预定间隔从姿势保持杆的左右两侧间隔开的姿势保持杆和嵌合片。 在快门帘的打开/关闭操作的过程中，第一引导体将姿势保持杆引导到轨道槽的相对位置。 第二引导体根据与姿势保持杆相对于轨道槽的相对侧第一位置调节的定时，将快门帘幕的下端部处的配合件引导到轨道槽的相对侧 引导体设置在构成导轨的轨道槽的上侧。
-
公开(公告)号：US07571899B2
公开(公告)日：2009-08-11
申请号：US10597627
申请日：2005-01-28
申请人： Hiroshi Kitasako , Masao Katsube , Katsuhiro Sakamoto , Junzo Sago , Hiroaki Tanaka , Jun Tsumori
发明人： Hiroshi Kitasako , Masao Katsube , Katsuhiro Sakamoto , Junzo Sago , Hiroaki Tanaka , Jun Tsumori
IPC分类号： B01F3/04
CPC分类号： B01F5/0268 , B01F1/0022 , B01F3/0446 , B01F2003/04879 , B01F2215/0052
摘要： A gas-liquid dissolving apparatus includes an intake unit that takes in to-be-treated water from an oxygen-deficient water area, an oxygen-containing gas supply unit, a bottomed gas-liquid dissolving chamber that has at least one hole formed in a lower portion and a top plate provided in an upper portion, a nozzle that ejects the gas supplied by the supplying unit and the water supplied by the intake unit, a gas-liquid separating chamber that has a gas-vent hole formed in an upper portion and a takeout port provided in a lower portion thereof, and a water supplying unit that returns the water taken out from the takeout port to the oxygen-deficient water area.
摘要翻译： 气液溶解装置包括从缺氧水区域吸入被处理水的进气单元，含氧气体供给单元，具有至少一个孔的底部气液溶解室， 设置在上部的下部和顶板，喷射由供给单元供给的气体和由进气单元供给的水的喷嘴，具有形成在上部的排气孔的气液分离室 部分和设置在其下部的取出口，以及将从取出口取出的水返回到缺水区域的供水单元。
-
公开(公告)号：US20060144530A1
公开(公告)日：2006-07-06
申请号：US10528574
申请日：2004-06-30
申请人： Toyohide Nagare , Hideki Tanemura , Atsushi Matsumura , Masahito Goto , Takashi Nagata , Katsuhiro Sakamoto
发明人： Toyohide Nagare , Hideki Tanemura , Atsushi Matsumura , Masahito Goto , Takashi Nagata , Katsuhiro Sakamoto
IPC分类号： E06B9/17
CPC分类号： E06B9/581 , E06B9/13 , E06B2009/585
摘要： When a fitting piece slipping out of a rail groove of a guide rail in connection with an excessive load on a shutter curtain is restored to the rail groove, the restoration is set to be reliably and noiselessly carried out. An posture holding bar 14 and fitting pieces 5 which are spaced from both right and left sides of the posture holding bar 14 at a predetermined interval are provided at the lower end portion of the shutter curtain 1, and a first guide body 15 for guiding the posture holding bar 14 to the opposing site to the rail groove 9a in the process of an opening/closing operation of the shutter curtain 1, and a second guide body 16 for guiding the fitting piece 5 at the lower end portion of the shutter curtain 1 to the opposing site to the rail groove 9a in conformity with a timing at which the posture holding bar 14 is positionally regulated to the opposing site to the rail groove 9a by the first guide body 15 are provided at the upper side of the rail groove 9a constituting the guide rail 4.
摘要翻译： 当与挡板上的过大负载相关的导轨的轨道槽滑出的配件被还原到轨道槽时，恢复被设定为可靠且无噪声地进行。 并且，在活门帘1的下端部设置有以预定间隔与姿势保持杆14的左右两侧隔开的姿势保持杆14和嵌合片5，以及第一引导体15， 姿势保持杆14在快门帘1的打开/关闭操作的过程中到相对于轨道槽9a的位置;以及第二引导体16，用于将安装片5引导到快门帘幕的下端部 1相对于轨道槽9a的相对位置设置在第一引导体15的上侧，其中姿势保持杆14通过第一引导体15位置调节到与轨道槽9a相对的位置的定时 轨道槽9a构成导轨4。
-
-
-
-
-
-
搜索结果
7 条记录 (耗时 0.024 秒)
