公开(公告)号：US20100168249A1

公开(公告)日：2010-07-01

申请号：US12710888

申请日：2010-02-23

申请人： Shiro KITAMURA ,  Takahiro UEDA

发明人： Shiro KITAMURA ,  Takahiro UEDA

IPC分类号： A61K31/122 ,  A61K8/35 ,  A23D9/007

CPC分类号： A61K31/122 ,  A21D2/14 ,  A21D2/165 ,  A23D7/0053 ,  A23D7/0056 ,  A23D9/007 ,  A23D9/013 ,  A23K20/111 ,  A23K20/158 ,  A23L33/10 ,  A23L33/115 ,  A23L33/12 ,  A61K8/355 ,  A61Q19/00

摘要： The invention provides a composition containing reduced coenzyme Q10, which is useful as a pharmaceutical product, food, cosmetic, animal drug, feed, and the like, as well as a stabilization method thereof. The oxidation of reduced coenzyme Q10 into oxidized coenzyme Q10 by molecular oxygen can be suppressed by setting, in a composition containing reduced coenzyme Q10 and at least one kind of oil component selected from the group consisting of fat, oil, a mixture thereof, fatty acid, wax and a surfactant, the weight ratio of the reduced coenzyme Q10 to the oil component to not less than 1/4 when the composition is a liquid, and not less than 1/9 when the composition is a solid.

摘要翻译： 本发明提供含有还原型辅酶Q10的组合物，其可用作药物产品，食品，化妆品，动物药物，饲料等，以及其稳定化方法。 还原型辅酶Q10通过分子氧氧化成氧化型辅酶Q10可以通过在含有还原型辅酶Q10的组合物和选自脂肪，油，其混合物，脂肪酸中的至少一种油成分 ，蜡和表面活性剂时，当组合物为液体时，还原型辅酶Q10与油性成分的重量比为1/4以上，当组合物为固体时为1/9以上。

公开(公告)号：US20110136191A1

公开(公告)日：2011-06-09

申请号：US13020500

申请日：2011-02-03

申请人： Kazuyoshi YAJIMA ,  Takahisa KATO ,  Akihisa KANDA ,  Shiro KITAMURA ,  Yasuyoshi UEDA

发明人： Kazuyoshi YAJIMA ,  Takahisa KATO ,  Akihisa KANDA ,  Shiro KITAMURA ,  Yasuyoshi UEDA

IPC分类号： C12P7/22

CPC分类号： C12P7/66 ,  C12P7/22

摘要： The present invention relates to a process for producing reduced coenzyme Q10 which comprises obtaining microbial cells containing reduced coenzyme Q10 at a ratio of not less than 70 mole % among the entire coenzymes Q10, optionally disrupting the cells and recovering thus produced reduced coenzyme Q10. The present invention also relates to a process for producing oxidized coenzyme Q10 which comprises either recovering oxidized coenzyme Q10 after oxidizing the above-mentioned microbial cells or disrupted product thereof, or recovering reduced coenzyme Q10 from the above-mentioned microbial cells or disrupted product thereof to oxidize thus-obtained reduced coenzyme Q10 thereafter. According to the processes of the present invention, reduced coenzyme Q10 and oxidized coenzyme Q10 can be produced simply on the industrial scale.

摘要翻译： 本发明涉及一种还原型辅酶Q10的制备方法，其包括在整个辅酶Q10中获得含有还原型辅酶Q10比例不小于70摩尔％的微生物细胞，任选地破坏细胞并回收所生成的还原型辅酶Q10。 本发明还涉及氧化型辅酶Q10的制造方法，该方法包括在氧化上述微生物细胞或其破坏的产物后回收氧化型辅酶Q10，或将还原型辅酶Q10从上述微生物细胞或其破坏性产物回收至 此后氧化由此得到的还原型辅酶Q10。 根据本发明的方法，可以简单地在工业规模上制备还原型辅酶Q10和氧化型辅酶Q10。