公开(公告)号：US20050140974A1

公开(公告)日：2005-06-30

申请号：US10507983

申请日：2003-03-14

申请人： Shouichi Irie ,  Takao Hisazumi ,  Norie Araki ,  Takashi Nagashima

发明人： Shouichi Irie ,  Takao Hisazumi ,  Norie Araki ,  Takashi Nagashima

IPC分类号： G01N21/67 ,  G01J3/30

CPC分类号： G01N21/67

摘要： A metal identification device of the present invention is characterized in that it includes an arc discharge device including a discharge electrode for causing a discharge between itself and an object to be identified so as to excite the object to be identified and cause it to emit light, an optic fiber for gathering light that has been emitted by the arc discharge device, a spectrophotometer for measuring an emission spectrum of the light that has been gathered by the optic fiber, a personal computer serving as an identification processing portion for identifying a type of the object to be identified by comparing data of the emission spectrum measured by the spectrophotometer and emission spectrum data of a plurality of standard samples stored in advance, and a damage processing portion for damaging at least some of the surface of the object to be identified.

摘要翻译： 本发明的金属识别装置的特征在于它包括一个电弧放电装置，它包括放电电极，用于使其自身与被识别物体之间的放电，以便激发被识别的物体并使其发光， 用于聚集由电弧放电装置发射的光的光纤，用于测量由光纤收集的光的发射光谱的分光光度计;用作识别处理部分的个人计算机，用于识别 通过比较由分光光度计测量的发射光谱的数据和预先存储的多个标准样品的发射光谱数据的数据和用于损坏要识别的对象的至少一些表面的损伤处理部分来识别对象。

公开(公告)号：US07948247B2

公开(公告)日：2011-05-24

申请号：US12441290

申请日：2007-09-14

申请人： Norie Araki ,  Hirofumi Iwakawa ,  Yoshiyuki Tani ,  Hiroshi Iwamoto

发明人： Norie Araki ,  Hirofumi Iwakawa ,  Yoshiyuki Tani ,  Hiroshi Iwamoto

IPC分类号： G01R27/08 ,  G01N27/00

CPC分类号： G01N27/041 ,  G01N21/31 ,  G01N21/3563 ,  G01N21/67

摘要： A metal identifying device precisely identifies a metal material in a metal member having a plurality of through-hole portions penetrating through the metal member. The metal identifying device of the present invention includes a measurement unit that obtains a measurement value by measuring an electrical property and/or optical property of a test object, a threshold value determination unit that determines a threshold value with use of a reference value obtained by measuring the property of a metal member having a metal composition to be identified and information indicating a ratio of the through-hole portions to a measurement area in the test object and/or information indicating a configuration of the through-hole portion, and a comparison/identification unit that identifies a metal composition of the test object by comparing the measurement value and the threshold value.

摘要翻译： 金属识别装置精确地识别具有穿透金属构件的多个通孔部分的金属构件中的金属材料。 本发明的金属识别装置包括：测量单元，通过测量测试对象的电气特性和/或光学特性来获得测量值;阈值确定单元，其使用由 测量具有要识别的金属组合物的金属构件的性质和指示通孔部分与测试对象中的测量区域的比率的信息和/或指示通孔部分的构造的信息，以及比较 /识别单元，其通过比较测量值和阈值来识别测试对象的金属组成。

公开(公告)号：US20130023574A1

公开(公告)日：2013-01-24

申请号：US13638836

申请日：2011-03-31

申请人： Norie Araki ,  Souhei Mizuguchi ,  Daiki Kobayashi ,  Nobuyuki Tsubota ,  Takashi Morikawa ,  Junichi Kuratsu ,  Masayo Wilson Morifuji

发明人： Norie Araki ,  Souhei Mizuguchi ,  Daiki Kobayashi ,  Nobuyuki Tsubota ,  Takashi Morikawa ,  Junichi Kuratsu ,  Masayo Wilson Morifuji

IPC分类号： G06F17/30 ,  A61P35/00 ,  A61K31/4188

CPC分类号： G16B20/00 ,  G01N2570/00 ,  G16B25/00 ,  G16B50/00

摘要： Provided are a method for generating a data set for integrated proteomics analysis, whereby expression level variations of both of proteins and genes can be integrally united together and, moreover, highly accurate and appropriate analysis results can be obtained compared with the existing cases where the expression variation amount of proteins or genes is singly analyzed, an integrated proteomics analysis method, a method for identifying a protein causative of a disease or the like using these methods, and a method of using the same???. The aforesaid method for generating a data set for integrated proteomics analyses comprises: a protein identity number-assigning step for assigning common identity numbers to the expression variation amount data of individual proteins; a gene identity number-assigning step for assigning common identity numbers to the expression variation amount data of individual genes; a data-binding step for binding together the set of the expression variation amount data; a data-rejecting step for rejecting, among the individual expression variation amount data constituting the thus bound data set, data showing a p-value equal to or greater than a specific level; and a data-selecting step for selecting one data, from a set of data having the same common identity number assigned thereto, on the basis of a definite requirement to thereby generate the data set to be subjected to integrated proteomics analyses. Further, the data set for integrated proteomics analyses thus generated is subjected to GO analysis and network analysis to thereby identify a protein causative of a disease, a pathological condition or the like. Furthermore, the causative protein thus identified is usable, for example, a tumor marker or a clinical target.

公开(公告)号：US20090261848A1

公开(公告)日：2009-10-22

申请号：US12441290

申请日：2007-09-14

申请人： Norie Araki ,  Hirofumi Iwakawa ,  Yoshiyuki Tani ,  Hiroshi Iwamoto

发明人： Norie Araki ,  Hirofumi Iwakawa ,  Yoshiyuki Tani ,  Hiroshi Iwamoto

IPC分类号： G01R27/08 ,  G01N21/55

CPC分类号： G01N27/041 ,  G01N21/31 ,  G01N21/3563 ,  G01N21/67

摘要： A metal identifying device precisely identifies a metal material in a metal member having a plurality of through-hole portions penetrating through the metal member. The metal identifying device of the present invention includes a measurement unit that obtains a measurement value by measuring an electrical property and/or optical property of a test object, a threshold value determination unit that determines a threshold value with use of a reference value obtained by measuring the property of a metal member having a metal composition to be identified and information indicating a ratio of the through-hole portions to a measurement area in the test object and/or information indicating a configuration of the through-hole portion, and a comparison/identification unit that identifies a metal composition of the test object by comparing the measurement value and the threshold value.

摘要翻译： 金属识别装置精确地识别具有穿透金属构件的多个通孔部分的金属构件中的金属材料。 本发明的金属识别装置包括：测量单元，通过测量测试对象的电气特性和/或光学特性来获得测量值;阈值确定单元，其使用由 测量具有要识别的金属组合物的金属构件的性质和指示通孔部分与测试对象中的测量区域的比率的信息和/或指示通孔部分的构造的信息，以及比较 /识别单元，其通过比较测量值和阈值来识别测试对象的金属组成。

公开(公告)号：US06613537B2

公开(公告)日：2003-09-02

申请号：US09795342

申请日：2001-02-28

申请人： Ko Nakamura ,  Seikoh Horiuchi ,  Norie Araki

发明人： Ko Nakamura ,  Seikoh Horiuchi ,  Norie Araki

IPC分类号： G01N33543

CPC分类号： C07D471/04 ,  C07K16/44 ,  Y10S436/811 ,  Y10S436/815

摘要： The present invention is drawn to pyrrolopyridinium derivatives having a new structural skeleton, preferably containing an intramolecular hemiacetal, which is clearly different from any known Advanced Glycation Endproduct (AGE) and which, when present in an organism, has a bioactivity unlike the conventional AGE. The present invention provides pyrrolopyridinium derivatives and pharmaceutically acceptable salts thereof, an antibody prepared from said derivatives as a hapten, a method for the diagnosis of diabetes, diabetic complications, renal failure, dialysis-related complications, amyloidosis, aging, diseases accompanied by aging, etc. using said derivatives or an antibody prepared therefrom and a method for evaluating effectiveness of pharmaceuticals used to treat diabetes, diabetes-related diseases, dialysis-related complications, aging, diseases accompanied by aging, etc.