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2 条记录 (耗时 0.014 秒)

    Cordless light source
    1.
    发明授权
    Cordless light source 失效
    无线光源

    公开(公告)号：US5530632A

    公开(公告)日：1996-06-25

    申请号：US305141

    申请日：1994-09-13

    申请人： Shuji Shikano ,  Misuzu Hasobe ,  Yasuji Matsuoka

    发明人： Shuji Shikano ,  Misuzu Hasobe ,  Yasuji Matsuoka

    IPC分类号： A61C5/00 ,  A61C13/15

    CPC分类号： A61C19/004 ,  Y10S362/804

    摘要： The first purpose of the invention is to provide cordless light irradiation in which a stable amount of light is emitted when irradiating, and moreover, the device can be made compact. The second purpose is to offer a cordless light irradiation device that can control the battery temperature during use to a lower temperature than in the past.Halogen lamp 1 equipped with a reflective mirror and batteries 4 are housed in handpiece 2. The device is equipped with battery case 3 that is provided with ventilation holes 5, cooling fan 6 and optical filter 7, and lamp guide 8 is provided on the terminal of handpiece 2.

    摘要翻译： 本发明的第一个目的是提供在照射时发射稳定量的光的无绳光照射，此外，可以使该装置紧凑。 第二个目的是提供一种无绳光照射装置，其能够在使用期间将电池温度控制到比过去更低的温度。 配备有反射镜和电池4的卤素灯1被容纳在手持件2中。该装置配备有设置有通风孔5，冷却风扇6和滤光器7的电池壳体3，并且在导体 的手机2。

    Sequestration of ass in the periphery in the absence of immunomodulating agent as a therapeutic approach for the treatment or prevention of beta-amyloid related diseases
    2.
    发明申请
    Sequestration of ass in the periphery in the absence of immunomodulating agent as a therapeutic approach for the treatment or prevention of beta-amyloid related diseases 审中-公开
    在不存在免疫调节剂的情况下外周的屁股的封存作为治疗或预防β-淀粉样蛋白相关疾病的治疗方法

    公开(公告)号：US20050227941A1

    公开(公告)日：2005-10-13

    申请号：US10499125

    申请日：2002-12-17

    申请人： Karen Duff ,  Yasuji Matsuoka

    发明人： Karen Duff ,  Yasuji Matsuoka

    IPC分类号： A61K31/192 ,  A61K31/535 ,  A61K31/655 ,  A61K31/70 ,  A61K31/739 ,  A61K38/17 ,  G01N33/53 ,  G01N33/537 ,  G01N33/543 ,  G01N33/68

    CPC分类号： A61K31/739 ,  A61K31/192 ,  A61K31/535 ,  A61K31/655 ,  A61K31/70 ,  A61K38/1709 ,  G01N33/6896 ,  G01N2800/52

    摘要： The present invention describes a method of administering an Aβ-binding agent or drug which has affinity for amyloid beta (Aβ) in the periphery (blood) and reducing Aβ levels in the brain without the need for the agent or drug to enter the brain itself. The Aβ-binding agents utilized in the methods of the invention are preferably non-immunomodulating agents (e.g., antigenic peptides or antibodies) and bind to Aβ in the periphery, or blood. Such compounds do not significantly cross the blood/brain barrier, and yet they lower amyloid (Aβ) levels in the brain, thereby serving as safer, therapeutic and prophylactic treatments against diseases associated with Aβ in the brain, e.g., Alzheimer's Disease and amyloid angiopathy, as well as against other AD-related amyloidoses.

    摘要翻译： 本发明描述了一种在外周（血液）中对淀粉样蛋白β（Abeta）具有亲和性并降低脑中Abeta水平而不需要药物或药物进入脑本身的Abeta结合剂或药物的方法 。 在本发明的方法中使用的抗原结合剂优选为非免疫调节剂（例如抗原肽或抗体）并且结合外周的Abeta或血液。 这些化合物不会显着穿过血液/脑屏障，但它们降低大脑中的淀粉样蛋白（Abeta）水平，从而对于与脑中的Abeta相关的疾病，例如阿尔茨海默氏病和淀粉样血管病变，作为更安全，治疗和预防性治疗 ，以及与其他AD相关的淀粉样变性。