公开(公告)号：US20150045717A1

公开(公告)日：2015-02-12

申请号：US14513856

申请日：2014-10-14

申请人： ShuntCheck, Inc.

发明人： Marek Swoboda ,  Matias Gabriel Hochman ,  Mark Evan Mattiucci ,  Frederick J. Fritz

IPC分类号： A61M27/00 ,  A61B5/03 ,  A61B5/01

CPC分类号： A61M27/006 ,  A61B5/01 ,  A61B5/031 ,  A61B5/032 ,  A61M5/168 ,  A61M5/16836 ,  G01F1/684

摘要： A system for measuring quantitative CSF flow in shunt tubing implanted under the skin. The system includes an array of thermo-sensors clustered in three sections, cooling device, placed on the skin surface and an associated data acquisition and analysis device. Two sensor sections are placed over the shunt on the skin and measure real time temperature responses related to CSF movement. One array placed adjacent the cooling device collects data on thermal properties of skin including skin thermal conductivity, specific heat, diffusivity, perfusion, and thermal inertia. The method involves assessing thermal properties of skin and measuring CSF flow in shunt tubing. The method is useful for shunt patency assessment, CSF valve adjustment procedures and CSF flow measurements related to CSF over drainage. Alternatively, only one section of sensors need be used when determining relative CSF flow, without the need to determine thermal skin properties and by applying the cooling device continuously.

摘要翻译： 用于测量植入皮下的分流管中定量CSF流量的系统。 该系统包括聚集在三个部分的热传感器阵列，放置在皮肤表面上的冷却装置和相关的数据采集和分析装置。 将两个传感器部分放置在皮肤上的分流器上，并测量与CSF运动相关的实时温度响应。 靠近冷却装置放置的一个阵列收集关于皮肤热性质的数据，包括皮肤热导率，比热，扩散性，灌注和热惯性。 该方法包括评估皮肤的热性质并测量分流管中的CSF流量。 该方法对于分流通气评估，脑脊液阀调节程序和与流量相关的CSF流量测量有用。 或者，当确定相对CSF流量时，仅需要使用一个传感器部分，而不需要确定热皮肤特性并且连续地施加冷却装置。

公开(公告)号：US20150201882A1

公开(公告)日：2015-07-23

申请号：US14417932

申请日：2013-07-25

申请人： ShuntCheck, Inc.

发明人： Marek Swoboda ,  Matias Gabriel Hochman

IPC分类号： A61B5/00 ,  A61M27/00 ,  A61B5/01

CPC分类号： A61B5/4851 ,  A61B5/01 ,  A61B5/031 ,  A61B5/4058 ,  A61B5/4836 ,  A61B5/7278 ,  A61B2560/0223 ,  A61B2560/0412 ,  A61B2562/0271 ,  A61B2562/043 ,  A61B2562/164 ,  A61M27/006

摘要： An apparatus and method for determining a continuous CSF flow rate in an implanted CSF shunt in real-time. The system/method utilize a Peltier sensor formed on a flexible pad that is placed against the patient's skin. The Peltier sensor includes a Peltier device coupled to a thermal resistor that is contact with the patient's skin over the CSF shunt location. The Peltier device is operated continuously, controlled by the Peltier temperature sensor to a predetermined temperature that is below the patient's core temperature to form a temperature differential that causes any heat generated by the skin/CSF flow to be detected by a skin temperature sensor and the Peltier temperature sensor. Upstream and downstream temperature sensors, as well as control temperature sensors, are utilized to form a zero flow rate baseline that is used to calibrate a Peltier signal that corresponds to a real-time CSF flow rate. A sensor processing device processes all sensor data for generating the zero flow rate baseline and the Peltier signal.

摘要翻译： 一种用于确定植入式CSF分流器中的连续CSF流速的装置和方法。 该系统/方法利用形成在柔性垫上的珀尔帖传感器，其被放置在患者皮肤上。 珀尔帖传感器包括耦合到热电阻器的珀尔帖装置，其在CSF分流位置处与患者的皮肤接触。 佩尔贴装置连续操作，由珀尔帖温度传感器控制到低于患者核心温度的预定温度，以形成温度差，使由皮肤温度传感器检测皮肤/ CSF流产生的任何热量，并且 珀尔帖温度传感器 上游和下游温度传感器以及控制温度传感器被用于形成用于校准对应于实时CSF流速的珀尔帖信号的零流量基线。 传感器处理装置处理用于生成零流量基线和珀尔帖信号的所有传感器数据。