公开(公告)号：US20180303431A1

公开(公告)日：2018-10-25

申请号：US15763355

申请日：2016-09-23

申请人： ESSILOR INTERNATIONAL

发明人： Coralie BARRAU ,  Denis ROUSSEAU ,  Marie LORE ,  Thierry VILLETTE

IPC分类号： A61B5/00 ,  A61B5/11 ,  G16H50/30 ,  G16H10/60 ,  G16H10/20

CPC分类号： A61B5/7275 ,  A61B5/11 ,  A61B5/1103 ,  A61B5/4058 ,  A61B5/4094 ,  A61B5/4815 ,  A61B5/6803 ,  A61B2560/0242 ,  A61B2560/0462 ,  G16H10/20 ,  G16H10/60 ,  G16H50/30

摘要： A user migraine analysis component comprises a memory configured to store computer executable instructions, and a processor for executing the computer executable instructions. The computer executable instructions comprise instructions for receiving at least a visual behavior parameter indicative of the real time visual behavior of the user, and determining the migraine risk of the user based on the analysis of the at least one visual behavior parameter.

公开(公告)号：US20180036053A1

公开(公告)日：2018-02-08

申请号：US15668329

申请日：2017-08-03

申请人： Elisandro R. Toscano ,  Michael B. Frankel ,  Yahya Mansour ,  Malek K, Mansour ,  Saam Zarrabi

发明人： Elisandro R. Toscano ,  Michael B. Frankel ,  Yahya Mansour ,  Malek K, Mansour ,  Saam Zarrabi

IPC分类号： A61B17/86 ,  A61F2/44 ,  A61F2/46 ,  A61B5/00 ,  A61F2/72 ,  A61B5/11 ,  A61C8/00 ,  A61B5/04

CPC分类号： A61B17/869 ,  A61B5/04001 ,  A61B5/0492 ,  A61B5/1112 ,  A61B5/4058 ,  A61B5/4836 ,  A61B5/686 ,  A61C8/0001 ,  A61C8/0012 ,  A61C8/0039 ,  A61C8/0053 ,  A61C8/0062 ,  A61C8/0068 ,  A61C8/0074 ,  A61C8/008 ,  A61F2/4455 ,  A61F2/468 ,  A61F2/72 ,  A61F2002/30649 ,  A61F2002/3067 ,  A61F2002/3084 ,  A61F2002/3085 ,  A61F2002/4666 ,  A61F2002/4668 ,  A61F2002/4672 ,  A61F2310/00023 ,  A61F2310/00089

摘要： Improvements in a dental/prosthetic implant is disclosed. The implant includes interior and exterior threaded surfaces. The use of both interior and exterior expanding threaded surfaces for integrations of the insert and a prosthetic with the same implant. The implant is immediately usable under load and promotes rapid integration with bone growth. The expanded insert essentially makes contact with the tapped bone surfaces where loads can be immediately applied so a person can utilize the prosthetic implant. The implant can further include security devices GPS, ID with medical records making removal of the implant difficult to extract. A cushioning member may be further integrated. The implant/abutment can include a surface with a plurality of contacts with sufficient gold contact points to attach residual nerve endings, during implanting surgery to provide nerve identification, send, receive, target so as to exploit proprioceptive memory or retraining.

公开(公告)号：US20170325718A1

公开(公告)日：2017-11-16

申请号：US15592839

申请日：2017-05-11

申请人： BRAGI GmbH

发明人： Peter Vincent Boesen ,  Friedrich Christian Förstner ,  Martin Steiner

IPC分类号： A61B5/11 ,  A61B5/00

CPC分类号： A61B5/1101 ,  A61B5/002 ,  A61B5/0022 ,  A61B5/0082 ,  A61B5/02 ,  A61B5/1112 ,  A61B5/1118 ,  A61B5/1121 ,  A61B5/1124 ,  A61B5/1126 ,  A61B5/14517 ,  A61B5/14542 ,  A61B5/18 ,  A61B5/4058 ,  A61B5/4082 ,  A61B5/4845 ,  A61B5/4866 ,  A61B5/6803 ,  A61B5/6817 ,  A61B5/6898 ,  A61B5/7475 ,  A61B2560/0242 ,  A61B2562/0219 ,  G16H40/67

摘要： A method of diagnosing and monitoring biologic dysfunction may include performing measurements utilizing sensors of wireless earpieces, analyzing the measurements, comparing the measurements to established norms, determining whether the measurements indicate biologic dysfunction. The measurements may include biologic data of a user or environmental data. The sensors may include inertial sensors or optical sensors. The biologic dysfunction may include neurologic dysfunction and the neurologic dysfunction may include intention tremor. The method may include reporting the biologic dysfunction to a user.

公开(公告)号：US20170182312A1

公开(公告)日：2017-06-29

申请号：US15301956

申请日：2015-04-08

申请人： CASE WESTERN RESERVE UNIVERSITY

发明人： Dominique M. Durand ,  Chen Qui

IPC分类号： A61N1/05 ,  A61B5/00 ,  A61B5/04

CPC分类号： A61N1/0558 ,  A61B5/04001 ,  A61B5/4029 ,  A61B5/4058 ,  A61B5/4064 ,  A61B5/6868 ,  A61B5/6877 ,  A61N1/0529 ,  A61N1/0539 ,  A61N1/0551

摘要： One aspect of the present disclosure can include a method for implanting a neural electrode in a fascicle including a target nerve. One step of the method can include inserting a microwire assembly into the fascicle. The microwire assembly can comprise a microwire body that is coiled around a needle introducer. Next, a portion of the microwire body can be uncoiled from around the needle introducer so that a distal end of the microwire body retains a spiral-shaped configuration. The needle introducer can then be withdrawn so that the spiral-shaped distal end of the microwire body remains implanted in the fascicle.

公开(公告)号：US09681821B2

公开(公告)日：2017-06-20

申请号：US14903029

申请日：2015-02-19

申请人： SYNAPTIVE MEDICAL (BARBADOS) INC.

发明人： Cameron Piron ,  Jeff Stainsby ,  Chad Harris

IPC分类号： A61B5/055 ,  A61B5/00 ,  A61B5/03 ,  G01R33/563

CPC分类号： A61B5/055 ,  A61B5/031 ,  A61B5/032 ,  A61B5/4058 ,  A61B5/4076 ,  A61B5/4809 ,  A61B2576/00 ,  G01R33/56341 ,  G01R33/56366

摘要： Systems and methods for providing quantitative measurements of global glymphatic flow of cerebrospinal fluid (“CSF”) using magnetic resonance imaging (“MRI”) are described. In general, images are obtained from a subject using flow-sensitive MRI techniques that are designed to be particularly sensitive to the glymphatic flow of CSF. Measures of glymphatic flow can be obtained while the subject is in an awake state and again while the subject is in a sleep state. Based on these two measurements, a biomarker that indicates a neurological state or disease can be generated.

公开(公告)号：US20150201882A1

公开(公告)日：2015-07-23

申请号：US14417932

申请日：2013-07-25

申请人： ShuntCheck, Inc.

发明人： Marek Swoboda ,  Matias Gabriel Hochman

IPC分类号： A61B5/00 ,  A61M27/00 ,  A61B5/01

CPC分类号： A61B5/4851 ,  A61B5/01 ,  A61B5/031 ,  A61B5/4058 ,  A61B5/4836 ,  A61B5/7278 ,  A61B2560/0223 ,  A61B2560/0412 ,  A61B2562/0271 ,  A61B2562/043 ,  A61B2562/164 ,  A61M27/006

摘要： An apparatus and method for determining a continuous CSF flow rate in an implanted CSF shunt in real-time. The system/method utilize a Peltier sensor formed on a flexible pad that is placed against the patient's skin. The Peltier sensor includes a Peltier device coupled to a thermal resistor that is contact with the patient's skin over the CSF shunt location. The Peltier device is operated continuously, controlled by the Peltier temperature sensor to a predetermined temperature that is below the patient's core temperature to form a temperature differential that causes any heat generated by the skin/CSF flow to be detected by a skin temperature sensor and the Peltier temperature sensor. Upstream and downstream temperature sensors, as well as control temperature sensors, are utilized to form a zero flow rate baseline that is used to calibrate a Peltier signal that corresponds to a real-time CSF flow rate. A sensor processing device processes all sensor data for generating the zero flow rate baseline and the Peltier signal.

摘要翻译： 一种用于确定植入式CSF分流器中的连续CSF流速的装置和方法。 该系统/方法利用形成在柔性垫上的珀尔帖传感器，其被放置在患者皮肤上。 珀尔帖传感器包括耦合到热电阻器的珀尔帖装置，其在CSF分流位置处与患者的皮肤接触。 佩尔贴装置连续操作，由珀尔帖温度传感器控制到低于患者核心温度的预定温度，以形成温度差，使由皮肤温度传感器检测皮肤/ CSF流产生的任何热量，并且 珀尔帖温度传感器 上游和下游温度传感器以及控制温度传感器被用于形成用于校准对应于实时CSF流速的珀尔帖信号的零流量基线。 传感器处理装置处理用于生成零流量基线和珀尔帖信号的所有传感器数据。

公开(公告)号：US20140058279A1

公开(公告)日：2014-02-27

申请号：US14073909

申请日：2013-11-07

申请人： TOSHIKAZU SHINBA ,  GM3 CO., LTD.,

发明人： TOSHIKAZU SHINBA

IPC分类号： A61B5/16 ,  A61B5/00 ,  A61B5/024

CPC分类号： A61B5/16 ,  A61B5/02405 ,  A61B5/165 ,  A61B5/4035 ,  A61B5/4058 ,  A61B5/7246 ,  A61B5/7275 ,  A61B5/7278 ,  G06F19/00

摘要： An evaluator includes a heart rate variability analyzer A having a heart rate measuring instrument, a heartbeat interval measuring instrument, a frequency analyzer, a sympathetic/parasympathetic nervous system index analyzer, and a psychiatric symptom/psychotic disorder onset risk calculator, and a random number generation analyzer having a random number input unit, a random number score calculation unit, and a display unit. Frequency analysis of a heart rate measurement and a heartbeat interval measurement of a subject is performed to determine a high-frequency index, a low-frequency index and a ratio therebetween,

摘要翻译： 评估器包括具有心率测量仪器，心跳间隔测量仪器，频率分析仪，交感神经/副交感神经系统指标分析仪和精神症状/精神病性发作风险计算器的心率变异性分析仪A和随机数 生成分析器，具有随机数输入单元，随机数分数计算单元和显示单元。 进行心率测量和受试者的心跳间隔测量的频率分析以确定高频指数，低频指数及其之间的比率，

公开(公告)号：US20130307686A1

公开(公告)日：2013-11-21

申请号：US13894583

申请日：2013-05-15

申请人： James C. FRAUENTHAL ,  Michael RAMALHO

发明人： James C. FRAUENTHAL ,  Michael RAMALHO

IPC分类号： A61B5/00 ,  A61B5/0205 ,  A61B5/12 ,  A61B5/145 ,  A61B3/113

CPC分类号： A61B5/746 ,  A61B3/113 ,  A61B5/0205 ,  A61B5/12 ,  A61B5/14532 ,  A61B5/14546 ,  A61B5/4058 ,  A61B5/441 ,  A61B5/7275 ,  A61B5/747 ,  G16H50/20

摘要： A system and method are provided whereby periodic measurements of autonomic reflex times of individuals are used as an early-warning indication that an undesirable physical condition, such as an undesirable blood-chemistry condition, may exist. This method correlates measurements of the reaction times of specific autonomic reflexes to more-definitive measurements for the medical condition being monitored for this early-warning assessment.

摘要翻译： 提供了一种系统和方法，其中使用个体的自主反射时间的周期性测量作为可能存在不期望的身体状况（例如不期望的血液化学状况）的早期警告指示。 该方法将特定自主反射的反应时间的测量与对该预警评估进行监测的医疗状况的更确定的测量相关联。

公开(公告)号：US20130253283A1

公开(公告)日：2013-09-26

申请号：US13428331

申请日：2012-03-23

申请人： Bryan Hudson ,  Stephanie Peabody-Hudson

发明人： Bryan Hudson ,  Stephanie Peabody-Hudson

IPC分类号： A61B5/00

CPC分类号： G16H50/20 ,  A61B5/4058 ,  G06F19/324 ,  G16H10/60 ,  G16H15/00

摘要： A system and method for monitoring treatment of central nervous system disorders of a patient. Initially, a plurality of patient symptoms are selected from a list of predetermined symptoms which correspond to NINDS common data elements. The symptoms are then measured in standardized units, and changes in the symptoms are recorded. The recorded changes are then standardized and an indication of the standardized changes is displayed. The above steps are and repeated until the monitoring, which may span the patient's lifetime, is concluded.

摘要翻译： 用于监测患者中枢神经系统疾病的治疗的系统和方法。 最初，从对应于NINDS公共数据元素的预定症状的列表中选择多个患者症状。 然后以标准单位测量症状，并记录症状的变化。 记录的变化然后被标准化，并显示标准化变化的指示。 上述步骤是重复的，直到可能跨越患者生命的监测结束。

公开(公告)号：US20130178829A1

公开(公告)日：2013-07-11

申请号：US13781936

申请日：2013-03-01

申请人： Ali R. Rezai ,  Anthony V. Caparso ,  Benjamin D. Pless

发明人： Ali R. Rezai ,  Anthony V. Caparso ,  Benjamin D. Pless

IPC分类号： A61M5/00 ,  A61N1/05

CPC分类号： A61N1/3611 ,  A61B5/0205 ,  A61B5/04001 ,  A61B5/1473 ,  A61B5/4029 ,  A61B5/4058 ,  A61B5/4836 ,  A61B5/6877 ,  A61M5/14276 ,  A61M5/1723 ,  A61M2205/50 ,  A61N1/0551 ,  A61N1/36021 ,  A61N1/36071

摘要： The present invention is directed to a method of treating a respiratory or pulmonary condition in a patient by transvascular neuromodulation of an adrenal gland or neural structures that innervate the adrenal gland or components thereof. Methods also include implanting a controller in the patient to control delivery of a therapy signal to the patient's adrenal gland. The therapy signal can be an electrical and/or chemical signal.

摘要翻译： 本发明涉及一种通过肾上腺或神经结构的血管神经调节来治疗患者的呼吸或肺部疾病的方法，所述神经结构支配肾上腺或其组分。 方法还包括将控制器植入患者体内以控制对患者的肾上腺的治疗信号的传递。 治疗信号可以是电和/或化学信号。