公开(公告)号：US20250008349A1

公开(公告)日：2025-01-02

申请号：US18824181

申请日：2024-09-04

Applicant: Siemens Healthcare Diagnostics Inc.

Inventor： Spencer Lin ,  Kwasi Osae-Kwapong ,  Omar Quraishi ,  Seema Sinha ,  Michele Smith ,  SunRay DiFrancesco ,  Ryan Spears ,  Dharini Rawal ,  Debra Hovanec-Burns ,  Robert Owens

IPC: H04W24/02 ,  A61K38/00 ,  A61K38/17 ,  C07K14/435 ,  C07K14/47 ,  G01N33/96 ,  H04B7/06 ,  H04L41/0806 ,  H04W8/00 ,  H04W72/044 ,  H04W84/18

Abstract: A human insulin-like growth factor (IGF) binding protein stock solution and method of making the same include a non-recombinant human IGF binding protein-3 (nr-IGFBP-3) in an aqueous buffered medium. The concentration of the nr-IGFBP-3 in the stock solution ranges from about 16 micrograms per milliliter (μg/ml) to about 40 μg/ml. A kit includes a set of calibrators for nr-IGFBP-3. The set of calibrators includes the nr-IGFBP-3 in different concentrations.

公开(公告)号：US20210072266A1

公开(公告)日：2021-03-11

申请号：US16949817

申请日：2020-11-16

Applicant: Siemens Healthcare Diagnostics Inc.

Inventor： Spencer Lin ,  Kwasi Osae-Kwapong ,  Omar Quraishi ,  Seema Sinha ,  Michele Smith ,  SunRay DiFrancesco ,  Ryan Spears ,  Dharini Rawal ,  Debra Hovanec-Burns ,  Robert Owens

IPC: G01N33/96 ,  C07K14/47 ,  H04B7/06 ,  H04L12/24 ,  H04W24/02 ,  H04W72/04 ,  C07K14/435

Abstract: A human insulin-like growth factor (IGF) binding protein stock solution and method of making the same include a non-recombinant human IGF binding protein-3 (nr-IGFBP-3) in an aqueous buffered medium. The concentration of the nr-IGFBP-3 in the stock solution ranges from about 16 micrograms per milliliter (μg/ml) to about 40 μg/ml. A kit includes a set of calibrators for nr-IGFBP-3. The set of calibrators includes the nr-IGFBP-3 in different concentrations.

公开(公告)号：US12167255B2

公开(公告)日：2024-12-10

申请号：US16949817

申请日：2020-11-16

Applicant: Siemens Healthcare Diagnostics Inc.

Inventor： Spencer Lin ,  Kwasi Osae-Kwapong ,  Omar Quraishi ,  Seema Sinha ,  Michele Smith ,  SunRay DiFrancesco ,  Ryan Spears ,  Dharini Rawal ,  Debra Hovanec-Burns ,  Robert Owens

IPC: H04W24/02 ,  A61K38/00 ,  A61K38/17 ,  C07K14/435 ,  C07K14/47 ,  G01N33/96 ,  H04B7/06 ,  H04L41/0806 ,  H04W8/00 ,  H04W72/044 ,  H04W84/18

Abstract: A human insulin-like growth factor (IGF) binding protein stock solution and method of making the same include a non-recombinant human IGF binding protein-3 (nr-IGFBP-3) in an aqueous buffered medium. The concentration of the nr-IGFBP-3 in the stock solution ranges from about 16 micrograms per milliliter (μg/ml) to about 40 μg/ml. A kit includes a set of calibrators for nr-IGFBP-3. The set of calibrators includes the nr-IGFBP-3 in different concentrations.

公开(公告)号：US20190018025A1

公开(公告)日：2019-01-17

申请号：US16067589

申请日：2016-12-28

Applicant: Siemens Healthcare Diagnostics Inc.

Inventor： Spencer Lin ,  Kwasi Osae-Kwapong ,  Omar Quraishi ,  Seema Sinha ,  Michele Smith ,  SunRay DiFrancesco ,  Ryan Spears ,  Dharini Rawal ,  Debra Hovanec-Burns ,  Robert Owens

IPC: G01N33/96 ,  C07K14/435

Abstract: A human insulin-like growth factor (IGF) binding protein stock solution and method of making the same include a non-recombinant human IGF binding protein-3 (nr-IGFBP-3) in an aqueous buffered medium. The concentration of the nr-IGFBP-3 in the stock solution ranges from about 16 micrograms per milliliter (μg/ml) to about 40 μg/ml. A kit includes a set of calibrators for nr-IGFBP-3. The set of calibrators includes the nr-IGFBP-3 in different concentrations that are within a range of from about 0.5 μg/ml to about 16 μg/ml, which is configured to span a suspected range of IGFBP-3 analyte levels in an immunoassay of patient samples.