Liver disease activity estimation with ultrasound medical imaging

    公开(公告)号:US11553901B2

    公开(公告)日:2023-01-17

    申请号:US16816351

    申请日:2020-03-12

    发明人: Yassin Labyed

    IPC分类号: A61B8/08 A61B8/00

    摘要: Ultrasound-based estimation of disease activity, such as for NAS or other activity index for NAFLD for liver disease, is provided. Ultrasound measures acoustic scatter and shear wave propagation parameters, such as measuring acoustic backscatter coefficient, shear wave velocity, and shear wave damping ratio. A score for the disease activity is determined from these scatter and shear wave propagation parameters. The physician may be assisted by relatively inexpensive and rapid ultrasound as compared to biopsy or MRI based scoring in scoring activity of a disease, such as NAFLD. Ultrasound imaging is more readily available and less expensive and MRI, and is non-invasive.

    MUSCLE CONTRACTION STATE TRIGGERING OF QUANTITATIVE MEDICAL DIAGNOSTIC ULTRASOUND

    公开(公告)号:US20210077067A1

    公开(公告)日:2021-03-18

    申请号:US16571331

    申请日:2019-09-16

    发明人: Yassin Labyed

    IPC分类号: A61B8/14 A61B8/08

    摘要: For quantitative ultrasound imaging with a medical diagnostic ultrasound scanner, muscle tissue is scanned in order to determine the state of contraction. Once the desired state is identified, then QUS imaging is triggered to quantify or measure a tissue property while the muscle is in the desired state. The values of the tissue property at a known state of contraction may be more diagnostically useful or informative. Comparisons of the tissue property across time and/or location may more accurately reflect diagnostic information due to the triggering.

    Compressional sound speed imaging using ultrasound

    公开(公告)号:US10799208B2

    公开(公告)日:2020-10-13

    申请号:US15700617

    申请日:2017-09-11

    摘要: For sound speed imaging, different receive apertures are used instead of multiple transmissions from different angles. Acoustic echoes from a same transmission are receive beamformed with different apertures of the transducer array. The axial shift between the beamformed signals from the different apertures is used to solve for the speed of sound at one or more locations. The resulting measure of the speed of sound is displayed as the speed of sound in the tissue and may be diagnostically or prognostically useful.

    Calibration for ARFI imaging
    8.
    发明申请

    公开(公告)号:US20190175150A1

    公开(公告)日:2019-06-13

    申请号:US15841177

    申请日:2017-12-13

    IPC分类号: A61B8/00 A61B8/14 A61B8/08

    摘要: A system and method includes transmission of an ultrasound push pulse toward material along a first axis, the ultrasound push pulse associated with a first frequency, a first F number, and a first focal depth, determination of displacement of the material along the axis in response to the push pulse, transmission of a second ultrasound pulse toward the material along the first axis, the second ultrasound pulse associated with a second frequency, a second F number, and a second focal depth substantially similar to the first frequency, the first F number, and the first focal depth, respectively, reception of echo signals from the material in response to the second ultrasound pulse, beamforming of the echo signals based on the first F number and a fixed focus at the first focal depth, determination of a magnitude of the beamformed echo signals along the axis, determination of relative elasticity of the material along the axis based on the determined displacement of the material along the axis and the magnitude of the beamformed echo signals along the axis, and generation of an image based on the determined relative elasticity of the material along the axis.

    Quantitative viscoelastic ultrasound imaging
    9.
    发明申请
    Quantitative viscoelastic ultrasound imaging 审中-公开
    定量粘弹性超声成像

    公开(公告)号:US20160302769A1

    公开(公告)日:2016-10-20

    申请号:US14688965

    申请日:2015-04-16

    IPC分类号: A61B8/08 A61B8/00

    摘要: Viscosity is included in the quantification by an ultrasound imaging system. The log of a spectrum of displacement as a function of time is determined for each of various locations subjected to a shear or other wave. Solving using the log as a function of location provides the complex wavenumber. Various viscoelastic parameters, such as loss modulus and storage modulus, are determined from the complex wavenumber.

    摘要翻译: 通过超声成像系统的量化包括粘度。 对于经受剪切或其他波浪的各个位置,确定作为时间的函数的位移谱的对数。 使用日志作为位置的函数来解决提供复杂的波数。 从复数波数确定各种粘弹性参数,例如损耗模量和储能模量。