公开(公告)号：US11504452B2

公开(公告)日：2022-11-22

申请号：US16328720

申请日：2017-08-30

Applicant: SofSera Corporation

Inventor： Yasumichi Kogai ,  Nobuo Aoi ,  Daisuke Nomi ,  Karl Kazushige Kawabe

IPC: A61L31/02 ,  A61L15/18 ,  A61L27/10 ,  A61L29/02 ,  C01B25/32 ,  C04B35/447 ,  C04B35/622 ,  A61L31/12 ,  A61L29/12 ,  A61L15/64 ,  A61L27/40 ,  B82Y5/00 ,  A61L27/46 ,  A61K6/838

Abstract: To provide a ceramic particle separable composite material having a calcium phosphate sintered body particle with which bioaffinity reduction and solubility change are suppressed as much as possible and which has a smaller particle diameter.
A ceramic particle separable composite material comprising a ceramic particle and a substrate, wherein: the ceramic particle and the substrate are chemically bonded to each other, or the ceramic particle physically adheres to or is embedded in the substrate; the ceramic particle has a particle diameter within a range of 10 nm to 700 nm; the ceramic particle is a calcium phosphate sintered body particle; and the ceramic particle contains no calcium carbonate.

公开(公告)号：US20200181026A1

公开(公告)日：2020-06-11

申请号：US16313686

申请日：2016-08-30

Applicant: SofSera Corporation

Inventor： Yasumichi Kogai ,  Nobuo Aoi ,  Daisuke Nomi ,  Karl Kazushige Kawabe

IPC: C04B35/447

Abstract: This invention has an object to provide a means for providing a calcium phosphate sintered body particle group that does not cause a phenomenon of bubble generation in any use mode thereof, and further has a smaller particle diameter.There is provided a ceramic particle group containing spherical ceramic particles, which is characterized in that the ceramic particle has a particle diameter within a range of 10 nm to 700 nm, and is a calcium phosphate sintered body particle, and further the ceramic particle group contains no calcium carbonate.

公开(公告)号：US11168031B2

公开(公告)日：2021-11-09

申请号：US16328629

申请日：2017-08-30

Applicant: SofSera Corporation

Inventor： Yasumichi Kogai ,  Nobuo Aoi ,  Daisuke Nomi ,  Karl Kazushige Kawabe

IPC: C04B35/447 ,  A61K6/838 ,  A61L27/32 ,  C01B25/32 ,  C04B35/64

Abstract: This invention has an object to provide a means for providing a calcium phosphate sintered body particle group that does not cause a phenomenon of bubble generation in any use mode thereof, and further has a smaller particle diameter.
There is provided a ceramic particle group containing spherical ceramic particles, which is characterized in that the ceramic particle has a particle diameter within a range of 10 nm to 700 nm, and is a calcium phosphate sintered body particle, and further the ceramic particle group contains no calcium carbonate.