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公开(公告)号：US12193903B2
公开(公告)日：2025-01-14
申请号：US17267574
申请日：2019-09-06
Applicant: Solventum Intellectual Properties Company
Inventor： David M. Wilson , Bradley D. Craig , Mark B. Agre , Kari A. McGee , Daimon K Heller , William V. Chiu , Gareth A. Hughes
IPC: C08J5/00 , A61C5/20 , A61K6/17 , A61K6/802 , A61K6/829 , A61K6/836 , C08F222/10 , C08F222/22 , C08J5/04
Abstract: The present disclosure provides a composite material. The composite material includes 20 to 40 weight percent (wt. %) of a polymerizable component; 6 to 40 wt. % of ceramic fibers; and 30 to 70 wt. % of nanoclusters. Each of the ceramic fibers has a diameter and a length, the ceramic fibers having an arithmetic mean diameter of 0.3 micrometers to 5 micrometers, and the length of fifty percent of the ceramic fibers (based on a total number of the ceramic fibers) is at least 10 micrometers and the length of ninety percent of the ceramic fibers is no greater than 500 micrometers. The present disclosure also provides a method of making the composite material. The method includes obtaining components and admixing the components to form a composite material. Further, the present disclosure provides a method of using a composite material including placing a composite material near or on a tooth surface, changing the shape of the composite material near or on a tooth surface, and hardening the composite material. In addition, the present disclosure provides dental products and kits. Hardened composite materials can exhibit high strength.
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公开(公告)号：US20240423755A1
公开(公告)日：2024-12-26
申请号：US18820899
申请日：2024-08-30
Applicant: Solventum Intellectual Properties Company
Inventor： Randilynn B. Christensen , Kenton D. Budd , Afshin Falsafi , Mahmut Aksit , Jana Ninkovic , Jie J. Liu , Mark B. Agre , Masayuki Nakamura , Jason W. Bjork , Bradley D. Craig , Richard P. Rusin , Paul J. Homnick , Joel D. Oxman , Yizhong Wang , Paul R. Klaiber , Bill H. Dodge
Abstract: A method of applying a two-part dental sealant is described comprising providing a syringe device comprising a cartridge including first and second chamber. The first chamber contains a first part of a dental sealant comprising a (meth)acrylate resin and an oxidizing curing agent. The second chamber contains a second part of a dental sealant comprising a (meth)acrylate resin and a reducing curing agent that reacts with the oxidizing curing agent of the first chamber. The first and/or second part of the dental sealant further comprise a single component or multiple components that neutralize acid and promote remineralization. The syringe device comprises a dispensing nozzle comprising a static mixer and an outlet at one end of the cartridge and a plunger at the opposing end of the cartridge. Also described is a kit for storing and applying the dental sealant is described.
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公开(公告)号：US12161523B2
公开(公告)日：2024-12-10
申请号：US15734357
申请日：2019-06-05
Applicant: Solventum Intellectual Properties Company
Inventor： Randilynn B. Christensen , Kenton D. Budd , Afshin Falsafi , Mahmut Aksit , Jana Ninkovic , Jie J. Liu , Mark B. Agre , Masayuki Nakamura , Jason W. Bjork , Bradley D. Craig , Richard P. Rusin , Paul J. Homnick , Joel D. Oxman , Yizhong Wang , Paul R. Klaiber
IPC: A61C5/64 , A61C5/68 , A61K6/17 , A61K6/61 , A61K6/62 , A61K6/71 , A61K6/818 , A61K6/851 , A61K6/853 , A61K6/876 , A61K6/887 , C08K9/10 , A61K6/889 , C08L33/10
Abstract: A hardenable (e.g. dental) compositions is described comprising an encapsulated material. The encapsulated material comprises a basic core material and an inorganic shell material having certain viscosity criteria. Also described are dispensing devices and kits are described comprising a hardenable (e.g. dental) composition comprising a liquid material and an encapsulated material wherein the encapsulated material comprises a basic core material and an inorganic shell material comprising a metal oxide surrounding the core. The dispensing devices and kits can facilitate the methods of applying the hardenable composition. The hardenable or hardened (e.g. cured) composition can provide various technical effects such as a delayed release of a basic core material, a delayed increase in basicity, promoting remineralization of a tooth or bone structure, and increasing the average alkaline phosphatase (ALP) activity of pulp cells. In some embodiments, the composition is a dental (e.g. sealant) composition for application to a tooth structure.
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公开(公告)号：US20250064555A1
公开(公告)日：2025-02-27
申请号：US18938820
申请日：2024-11-06
Applicant: Solventum Intellectual Properties Company
Inventor： Randilynn B. Christensen , Kenton D. Budd , Afshin Falsafi , Mahmut Aksit , Jana Ninkovic , Jie J. Liu , Mark B. Agre , Masayuki Nakamura , Jason W. Bjork , Bradley D. Craig , Richard P. Rusin , Paul J. Homnick , Joel D. Oxman , Yizhong Wang , Paul R. Klaiber
IPC: A61C5/64 , A61C5/68 , A61K6/17 , A61K6/61 , A61K6/62 , A61K6/71 , A61K6/818 , A61K6/851 , A61K6/853 , A61K6/876 , A61K6/887 , A61K6/889 , C08K9/10 , C08L33/10
Abstract: A hardenable (e.g. dental) compositions is described comprising an encapsulated material. The encapsulated material comprises a basic core material and an inorganic shell material having certain viscosity criteria. Also described are dispensing devices and kits are described comprising a hardenable (e.g. dental) composition comprising a liquid material and an encapsulated material wherein the encapsulated material comprises a basic core material and an inorganic shell material comprising a metal oxide surrounding the core. The dispensing devices and kits can facilitate the methods of applying the hardenable composition. The hardenable or hardened (e.g. cured) composition can provide various technical effects such as a delayed release of a basic core material, a delayed increase in basicity, promoting remineralization of a tooth or bone structure, and increasing the average alkaline phosphatase (ALP) activity of pulp cells. In some embodiments, the composition is a dental (e.g. sealant) composition for application to a tooth structure.
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