公开(公告)号：US20250041334A1

公开(公告)日：2025-02-06

申请号：US18718158

申请日：2022-11-28

Applicant: Solventum Intellectual Properties Company

Inventor： Ranjani V. Parthasarathy ,  Max A. Kruziki ,  Hannah C. Cohen

IPC: A61K33/32 ,  A61K33/26 ,  A61K33/30 ,  A61K47/02 ,  A61K47/34 ,  A61P31/04

Abstract: A method of suppressing microbial virulence. The method includes administering and/or applying a composition. The composition includes (a) a surfactant comprising (i) a polyethylene glycol compound comprising a fatty acid moiety, or (ii) a fatty acid containing compound. The composition further includes (b) (i) a phosphate containing compound, and (ii) a metal salt; and (c) an aqueous carrier. The surfactant is present in an amount of between 0.01 wt. % and 1 wt. %, based on the total weight of the composition.

公开(公告)号：US12295923B2

公开(公告)日：2025-05-13

申请号：US17418718

申请日：2019-12-23

Applicant: Solventum Intellectual Properties Company

Inventor： Rajan B. Bodkhe ,  Ranjani V. Parthasarathy ,  Matthew T. Scholz ,  Naimul Karim ,  Petra L. Kohler Riedi ,  Joseph J. Stoffel

IPC: A61K31/14 ,  A01N31/02 ,  A01N37/06 ,  A61K47/10 ,  A61K47/12 ,  A61K47/14 ,  A61K47/18 ,  A61K47/32 ,  A61P31/02 ,  A01N33/04 ,  A01N37/04

Abstract: Compositions including a quaternary amine antiseptic component having a concentration of at least about 0.04% by weight; a poly carboxylic acid chelator having a concentration of at least about 0.05 M and/or an alphahydroxy acid buffer having a concentration of at least about 0.05 M; a (C8-C12) 1,2 alkane diol; and optionally water are provided. The compositions have a pH greater than or equal to 3.5 and less than 5.5 at 23° C. In certain embodiments, water is present in the composition at a greater weight percent than each of the quaternary amine antiseptic component; the polycarboxylic acid chelator, if present; the alphahydroxy acid buffer, if present; and the (C8-C12) 1,2-alkane diol. In certain embodiments, water is present in the composition at a greater weight percent than any other component.

公开(公告)号：US20250144058A1

公开(公告)日：2025-05-08

申请号：US18838021

申请日：2023-02-13

Applicant: Solventum Intellectual Properties Company

Inventor： Kevin D. Landgrebe ,  Ranjani V. Parthasarathy ,  Katie F. Wlaschin

IPC: A61K31/191 ,  A61K9/00 ,  A61K31/194 ,  A61K47/18 ,  A61K47/38 ,  A61P31/12

Abstract: A method of preventing transmission of a virus from a mammalian subject. The method includes applying to a surface of the nasal cavity of the mammalian subject an aqueous composition. The aqueous composition includes a surfactant and a hydroxycarboxylic acid. The aqueous composition is at least substantially free of an antimicrobial agent. The aqueous composition has a viscosity of between 2,000 and 100,000 cps.