公开(公告)号：US08703486B2

公开(公告)日：2014-04-22

申请号：US13120508

申请日：2009-08-17

申请人： Sonia Néron ,  Annie Roy ,  Jessie Farah Fecteau

发明人： Sonia Néron ,  Annie Roy ,  Jessie Farah Fecteau

IPC分类号： C12N5/06 ,  C12N5/08 ,  C12N5/00

CPC分类号： C12N5/0635 ,  C07K16/00 ,  C07K2317/14 ,  C07K2317/21 ,  C12N2500/25 ,  C12N2501/2302 ,  C12N2501/231 ,  C12N2511/00

摘要： This application relates to an in vitro method of producing a polyclonal IgG preparation. The method comprises (i) placing a polyclonal B-cell population enriched in IgG-secreting B cells in a culture medium; and (ii) culturing the polyclonal B-cell population under conditions enabling the production of the polyclonal IgG preparation from the polyclonal B-cell population. This improved method enables the production of antibodies (preferably IgG) and facilitates long-term culture of polyclonal B-cell populations.

摘要翻译： 本申请涉及制备多克隆IgG制剂的体外方法。 该方法包括（i）将富含IgG分泌B细胞的多克隆B-细胞群放入培养基中; 和（ii）在能够从多克隆B细胞群产生多克隆IgG制备物的条件下培养多克隆B-细胞群体。 该改进的方法能够产生抗体（优选IgG）并促进多克隆B-细胞群体的长期培养。

公开(公告)号：US07836834B2

公开(公告)日：2010-11-23

申请号：US10585096

申请日：2005-01-07

申请人： Jean Brault ,  Annie Roy ,  Thierry Krick

发明人： Jean Brault ,  Annie Roy ,  Thierry Krick

IPC分类号： A47B11/00

CPC分类号： A47B13/081 ,  A47B13/003 ,  B25H1/02 ,  Y10T403/32057

摘要： The worktable comprises a work platform and a multidirectional coupling for operatively attaching the work platform to an external structure. The multidirectional coupling comprises a first linear assembly comprising a first translation member and a second translation member engaging the first translation member and linearly movable relative to and along the first translation member between first and second limit positions and according to a first translation axis. The multidirectional coupling also includes a second linear assembly comprising a third translation member and a fourth translation member engaging the third translation member and linearly movable relative to and along the third translation member between third and fourth limit positions and according to a second translation axis that is transversal to the first translation axis. The multidirectional coupling further includes a swivel assembly comprising a first swivel member and a second swivel member engaging the first swivel member and rotatable relative to the first swivel member about a swiveling axis that is transversal to both the first and the second translation axes. The work platform is allowed to be displaced along the first and second translation axes and rotated about the swiveling axis at any position of the work platform when the multidirectional coupling operatively attaches the work platform to the external structure.

摘要翻译： 工作台包括工作平台和用于将工作平台可操作地连接到外部结构的多向联接器。 所述多向联接器包括第一线性组件，所述第一直线组件包括第一平移构件和第二平移构件，所述第二平移构件与所述第一平移构件接合并且可相对于所述第一平移构件在第一和第二极限位置之间并且沿着所述第一平移轴线在所述第一平移构 多向联接器还包括第二直线组件，其包括第三平移构件和与第三平移构件接合的第四平移构件，并且可相对于第三平移构件在第三和第四极限位置之间并且沿着第三平移构件线性移动，并且根据第二平移轴线， 横向于第一平移轴。 所述多向联接器还包括旋转组件，所述旋转组件包括第一旋转构件和第二旋转构件，所述第二旋转构件与所述第一旋转构件接合并且相对于所述第一旋转构件可围绕围绕所述第一和第二平移轴横向的旋转轴线旋转。 允许工作平台沿着第一和第二平移轴线移位，并且当多向联接器将工作平台可操作地附接到外部结构时，在工作平台的任何位置处围绕旋转轴线旋转。

公开(公告)号：US20100101461A1

公开(公告)日：2010-04-29

申请号：US10585096

申请日：2005-01-07

申请人： Jean Brault ,  Annie Roy ,  Thierry Krick

发明人： Jean Brault ,  Annie Roy ,  Thierry Krick

IPC分类号： A47B13/08 ,  A47B11/00 ,  F16D1/12 ,  A47B1/10 ,  F16C29/02 ,  A47B37/00 ,  B25H1/14 ,  B25H1/02

CPC分类号： A47B13/081 ,  A47B13/003 ,  B25H1/02 ,  Y10T403/32057

摘要： The worktable comprises a work platform and a multidirectional coupling for operatively attaching the work platform to an external structure. The multidirectional coupling comprises a first linear assembly comprising a first translation member and a second translation member engaging the first translation member and linearly movable relative to and along the first translation member between first and second limit positions and according to a first translation axis. The multidirectional coupling also includes a second linear assembly comprising a third translation member and a fourth translation member engaging the third translation member and linearly movable relative to and along the third translation member between third and fourth limit positions and according to a second translation axis that is transversal to the first translation axis. The multidirectional coupling further includes a swivel assembly comprising a first swivel member and a second swivel member engaging the first swivel member and rotatable relative to the first swivel member about a swivelling axis that is transversal to both the first and the second translation axes. The work platform is allowed to be displaced along the first and second translation axes and rotated about the swivelling axis at any position of the work platform when the multidirectional coupling operatively attaches the work platform to the external structure.

摘要翻译： 工作台包括工作平台和用于将工作平台可操作地连接到外部结构的多向联接器。 所述多向联接器包括第一线性组件，所述第一直线组件包括第一平移构件和第二平移构件，所述第二平移构件与所述第一平移构件接合并且可相对于所述第一平移构件在第一和第二极限位置之间并且沿着所述第一平移轴线在所述第一平移构 多向联接器还包括第二直线组件，其包括第三平移构件和与第三平移构件接合的第四平移构件，并且可相对于第三平移构件在第三和第四极限位置之间并且沿着第三平移构件线性移动，并且根据第二平移轴线， 横向于第一平移轴。 所述多向联接器还包括旋转组件，所述旋转组件包括第一旋转构件和第二旋转构件，所述第二旋转构件与所述第一旋转构件接合并且相对于所述第一旋转构件可围绕围绕所述第一和第二平移轴横向的旋转轴线旋转。 允许工作平台沿着第一和第二平移轴线移位，并且当多向联接器将工作平台可操作地附接到外部结构时，在工作平台的任何位置处围绕旋转轴线旋转。