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1.
公开(公告)号:US09150835B2
公开(公告)日:2015-10-06
申请号:US13531356
申请日:2012-06-22
申请人: Soon Chun Chung , Hyun Min Koo , Jae Young Kim , Ji Eun Kim , Jin Woo Kim , Young kyoung Park , So Young Lee , Hwa Young Cho , Dae Huck Kweon , Jae Chan Park
发明人: Soon Chun Chung , Hyun Min Koo , Jae Young Kim , Ji Eun Kim , Jin Woo Kim , Young kyoung Park , So Young Lee , Hwa Young Cho , Dae Huck Kweon , Jae Chan Park
CPC分类号: C12N9/0006 , C12N15/81 , C12N15/815 , C12P7/56 , C12Y101/01027
摘要: A modified microorganism for high efficient production of lactic acid, an expression vector for constructing the modified microorganism, and a method of producing a lactic acid using the same are disclosed. The modified microorganism may produce lactic acid at a high level under acid conditions.
摘要翻译: 公开了一种用于高效生产乳酸的改性微生物,用于构建修饰微生物的表达载体和使用其的乳酸生产方法。 改性微生物可在酸性条件下高水平生产乳酸。
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公开(公告)号:US08541212B2
公开(公告)日:2013-09-24
申请号:US13368953
申请日:2012-02-08
申请人: Jae Young Kim , Jae Chan Park , Sung Min Park , Hyun Min Koo , Byung Jo Yu , Hwa Young Cho , Young kyoung Park
发明人: Jae Young Kim , Jae Chan Park , Sung Min Park , Hyun Min Koo , Byung Jo Yu , Hwa Young Cho , Young kyoung Park
IPC分类号: C12P7/62
CPC分类号: C12P7/42 , C12N9/0006 , C12N9/1029 , C12Y101/01001 , C12Y101/01027 , C12Y203/01008
摘要: A method of increasing 3-HP production efficiency by inhibiting expression of a lactate dehydrogenase, a phosphotransacetylase, and an alcohol dehydrogenase in production of 3-HP using a malonic semialdehyde reduction pathway to prevent metabolite leak and increase a malonyl-CoA pool is disclosed.
摘要翻译: 公开了一种通过抑制乳酸脱氢酶,磷酸转乙酰酶和醇脱氢酶在产生3-HP中的表达而使用丙二醛半醛还原途径来预防代谢物泄漏并增加丙二酰辅酶A池的3-HP生产效率的方法。
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