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公开(公告)号:US11306294B2
公开(公告)日:2022-04-19
申请号:US16759125
申请日:2018-10-26
申请人: Sorbonne Universite , INSERM (Institut National de la Santé et de la Recherche Médicale) , Assistance Publique—Hôpitaux de Paris
发明人: Bertrand Bellier , David Klatzmann
IPC分类号: A61K39/00 , A61K38/17 , A61K39/12 , A61K9/00 , A61K39/385 , C12N7/00 , A61P29/00 , C12N15/86 , A61P37/08 , A61K35/76 , C07K14/005 , C07K14/705 , A61K35/12
摘要: The invention relates to a virus-like particle comprising an autoantigen and an immunoregulatory molecule exposed on its surface. The invention also relates to the use of said particle in the treatment of an autoimmune disease.
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公开(公告)号:US20210299195A1
公开(公告)日:2021-09-30
申请号:US16759591
申请日:2018-10-28
申请人: Sorbonne Universite , INSERM (Institut National de la Santé et de la Recherche Médicale) , Assistance Publique - Hôpitaux de Paris
发明人: Bertrand Bellier , David Klatzmann
IPC分类号: A61K35/76 , C07K14/705 , C07K14/005 , C12N7/00 , A61P37/08
摘要: The invention relates to a virus-like particle comprising an allergen and an immunoregulatory molecule exposed on its surface. The invention also relates to the use of said particle in the treatment of an allergy.
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公开(公告)号:US20200347363A1
公开(公告)日:2020-11-05
申请号:US16759125
申请日:2018-10-26
申请人: Sorbonne Universite , INSERM (Institut National de la Santé et de la Recherche Médicale) , Assistance Publique - Hôpitaux de Paris
发明人: Bertrand Bellier , David Klatzmann
摘要: The invention relates to a virus-like particle comprising an autoantigen and an immunoregulatory molecule exposed on its surface. The invention also relates to the use of said particle in the treatment of an autoimmune disease.
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公开(公告)号:US10376564B2
公开(公告)日:2019-08-13
申请号:US15124734
申请日:2015-03-10
申请人: SORBONNE UNIVERSITE , ASSISTANCE PUBLIQUE—HÔPITAUX DE PARIS , CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE
发明人: David Klatzmann , Bertrand Bellier
摘要: The present invention relates to the use of interleukin-2 (IL-2) for treating a food allergy, either by inducing non-specific tolerance against food allergens, or in a desensitization protocol in combination with a food allergen.
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