公开(公告)号：US10188593B2

公开(公告)日：2019-01-29

申请号：US15625340

申请日：2017-06-16

申请人： Spray-Tek, Inc.

发明人： Jiten Odhavji Dihora ,  Caroline Rachel Multari

IPC分类号： A61K8/02 ,  A61K8/25 ,  A61K8/73 ,  A61K8/92 ,  A61K9/16 ,  A61Q5/02 ,  A61Q5/12 ,  C09K3/30 ,  C11D3/00 ,  C11D3/08 ,  C11D3/12 ,  C11D3/22 ,  C11D3/37 ,  C11D3/50 ,  A01N25/28 ,  A23L27/00 ,  A61Q13/00 ,  A61Q15/00 ,  A61Q19/00 ,  A61Q19/10 ,  B01J13/04 ,  C11D17/00 ,  F28D20/02

摘要： Disclosed are: (a) controlled release matrix particles containing 10-70 wt. % of a hydrophobic active ingredient, 21-72 wt. % of a polysaccharide, 3.80-12 wt. % of a crosslinking agent, 1.00-6 wt. % of a catalyst and 0.10-5 wt. % of a silica flow aid; (b) controlled release core/shell particles containing 10-70 wt. % of a hydrophobic active ingredient, 1.0-3.2 wt. % of an epoxidized oil, 21-64 wt. % of a polysaccharide, 7.6-23% of an amine-functionality containing material, and 0.10-5 wt. % of a silica flow aid; and (c) hybrid particles wherein the core/shell particles are contained in a matrix. Also disclosed are methods for making the particles and compositions containing the particles.