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    Mitral heart valve replacement
    1.
    发明授权
    Mitral heart valve replacement 有权

    公开(公告)号：US10299921B2

    公开(公告)日：2019-05-28

    申请号：US15591380

    申请日：2017-05-10

    Applicant: St. Jude Medical, Cardiology Division, Inc.

    Inventor： Theodore Paul Dale ,  Katherine A. Ahmann ,  Brian Joseph Perszyk ,  Mathias Charles Glimsdale ,  Kristopher Henry Vietmeier

    IPC: A61F2/24

    Abstract: A prosthetic heart valve having an inflow end, an outflow end and a longitudinal axis extending from the inflow end to the outflow end includes a collapsible and expandable stent including a plurality of cells arranged in at least one row extending around a circumference of the stent. The stent further includes at least one engaging arm joined to one of the cells adjacent the outflow end and having a free end extending toward the inflow end, the engaging arm being movable between a loaded condition in which the engaging arm is oriented substantially parallel with the longitudinal axis of the stent, a partially-released condition in which the engaging arm forms a first angle with the longitudinal axis of the stent, and a fully-released condition in which the engaging arm forms a second angle with the longitudinal axis of the stent, the first angle being larger than the second angle.

    MITRAL HEART VALVE REPLACEMENT
    2.
    发明申请
    MITRAL HEART VALVE REPLACEMENT 审中-公开

    公开(公告)号：US20170325945A1

    公开(公告)日：2017-11-16

    申请号：US15591380

    申请日：2017-05-10

    Applicant: St. Jude Medical, Cardiology Division, Inc.

    Inventor： Theodore Paul Dale ,  Katherine A. Ahmann ,  Brian Joseph Perszyk ,  Mathias Charles Glimsdale ,  Kristopher Henry Vietmeier

    IPC: A61F2/24

    CPC classification number: A61F2/2418 ,  A61F2/2412 ,  A61F2210/0014 ,  A61F2220/0008 ,  A61F2250/006

    Abstract: A prosthetic heart valve having an inflow end, an outflow end and a longitudinal axis extending from the inflow end to the outflow end includes a collapsible and expandable stent including a plurality of cells arranged in at least one row extending around a circumference of the stent. The stent further includes at least one engaging arm joined to one of the cells adjacent the outflow end and having a free end extending toward the inflow end, the engaging arm being movable between a loaded condition in which the engaging arm is oriented substantially parallel with the longitudinal axis of the stent, a partially-released condition in which the engaging arm forms a first angle with the longitudinal axis of the stent, and a fully-released condition in which the engaging arm forms a second angle with the longitudinal axis of the stent, the first angle being larger than the second angle.

    Attachment of Leaflets to Prosthetic Heart Valve
    4.
    发明申请
    Attachment of Leaflets to Prosthetic Heart Valve 审中-公开

    公开(公告)号：US20200093590A1

    公开(公告)日：2020-03-26

    申请号：US16568345

    申请日：2019-09-12

    Applicant: St. Jude Medical, Cardiology Division, Inc.

    Inventor： Jay Reimer ,  Katherine A. Ahmann ,  Mai Moua

    IPC: A61F2/24

    Abstract: A prosthetic mitral valve may include a collapsible stent including a plurality of struts, a plurality of cells arranged in circumferential rows, the circumferential rows including a first row at an outflow end of the stent and a second row at an inflow end of the stent, and a plurality of strut intersections where at least two of the struts connect to one another. A cuff is attached to the stent. A prosthetic valve assembly is adapted to allow blood to flow in only one direction through the valve. The prosthetic valve assembly includes a first prosthetic leaflet having a first end attached directly to a first one of the strut intersections, and a second prosthetic leaflet having a first end attached directly to the first strut intersection. The first strut intersection is partially formed of one of the struts of one of the cells in the first row.

    Method Of Preparing Calcification-Resistant Bioprosthetic Tissue
    5.
    发明申请
    Method Of Preparing Calcification-Resistant Bioprosthetic Tissue 审中-公开

    公开(公告)号：US20190001023A1

    公开(公告)日：2019-01-03

    申请号：US16023436

    申请日：2018-06-29

    Applicant: St. Jude Medical, Cardiology Division, Inc.

    Inventor： Paul E. Ashworth ,  Chad Joshua Green ,  Jay Reimer ,  Katherine A. Ahmann ,  David A. Panus

    IPC: A61L27/36 ,  A61L27/50 ,  A61F2/24

    Abstract: Methods of preparing calcification-resistant bioprosthetic tissue include providing fresh biological tissue, cross-linking the tissue, treating the cross-linked tissue with an alcohol for a time sufficient to allow the alcohol to be diffused into the tissue, and treating the alcohol-treated fixed tissue with a polyol for a time sufficient to allow fluid in the tissue to be replaced by the polyol. The methods may include sterilizing the cross-linked tissue in a solution including propylene oxide or peracetic acid either before or after the alcohol treatment step; or drying the alcohol/polyol-treated, cross-linked tissue, sterilizing the dried tissue by exposure to ethylene oxide or peracetic acid, and storing the sterilized tissue in a dry, ambient environment. The treated tissue may be a tissue component for a bioprosthetic valve, a valve assembly for a bioprosthetic valve or a fully assembled bioprosthetic valve incorporating the tissue.

    Leaflet in configuration for function in various shapes and sizes
    6.
    发明授权
    Leaflet in configuration for function in various shapes and sizes 有权
    小册子配置为各种形状和大小的功能

    公开(公告)号：US09554902B2

    公开(公告)日：2017-01-31

    申请号：US13781423

    申请日：2013-02-28

    Applicant: St. Jude Medical, Cardiology Division, Inc.

    Inventor： Peter Nicholas Braido ,  Katherine A. Ahmann ,  Mina Safwat Fahim ,  Jeffrey J. Allison ,  Andrea L. McCarthy

    IPC: A61F2/24

    CPC classification number: A61F2/2418 ,  A61F2/2412 ,  A61F2220/005 ,  A61F2220/0066 ,  A61F2220/0075 ,  A61F2250/0017 ,  F04C2270/0421

    Abstract: A prosthetic heart valve includes a collapsible and expandable stent having a proximal end, a distal end, an annulus section adjacent the proximal end and an aortic section adjacent the distal end. The heart valve further includes a plurality of commissure features disposed on the stent, and a collapsible and expandable valve assembly, the valve assembly including a plurality of leaflets connected to the plurality of commissure features, each of the plurality of leaflets having a free edge and being configured to have a tension line aligned near the free edge to prevent backflow.

    Abstract translation: 假体心脏瓣膜包括可折叠和可扩张的支架，其具有近端，远端，邻近近端的环形部分和与远端相邻的主动脉部分。 心脏瓣膜还包括设置在支架上的多个连合部件，以及可折叠和可膨胀的阀组件，所述阀组件包括连接到所述多个连合部件的多个传单，所述多个传单中的每一个具有自由边缘， 被配置成具有在自由边缘附近对齐的张力线以防止回流。

    Attachment of leaflets to prosthetic heart valve
    9.
    发明授权
    Attachment of leaflets to prosthetic heart valve 有权

    公开(公告)号：US11284996B2

    公开(公告)日：2022-03-29

    申请号：US16568345

    申请日：2019-09-12

    Applicant: St. Jude Medical, Cardiology Division, Inc.

    Inventor： Jay Reimer ,  Katherine A. Ahmann ,  Mai Moua

    IPC: A61F2/24

    Abstract: A prosthetic mitral valve may include a collapsible stent including a plurality of struts, a plurality of cells arranged in circumferential rows, the circumferential rows including a first row at an outflow end of the stent and a second row at an inflow end of the stent, and a plurality of strut intersections where at least two of the struts connect to one another. A cuff is attached to the stent. A prosthetic valve assembly is adapted to allow blood to flow in only one direction through the valve. The prosthetic valve assembly includes a first prosthetic leaflet having a first end attached directly to a first one of the strut intersections, and a second prosthetic leaflet having a first end attached directly to the first strut intersection. The first strut intersection is partially formed of one of the struts of one of the cells in the first row.

    Method of preparing calcification-resistant bioprosthetic tissue
    10.
    发明授权
    Method of preparing calcification-resistant bioprosthetic tissue 有权

    公开(公告)号：US10722613B2

    公开(公告)日：2020-07-28

    申请号：US16023436

    申请日：2018-06-29

    Applicant: St. Jude Medical, Cardiology Division, Inc.

    Inventor： Paul E. Ashworth ,  Chad Joshua Green ,  Jay Reimer ,  Katherine A. Ahmann ,  David A. Panus

    IPC: A61L27/36 ,  A61F2/24 ,  A61L27/50

    Abstract: Methods of preparing calcification-resistant bioprosthetic tissue include providing fresh biological tissue, cross-linking the tissue, treating the cross-linked tissue with an alcohol for a time sufficient to allow the alcohol to be diffused into the tissue, and treating the alcohol-treated fixed tissue with a polyol for a time sufficient to allow fluid in the tissue to be replaced by the polyol. The methods may include sterilizing the cross-linked tissue in a solution including propylene oxide or peracetic acid either before or after the alcohol treatment step; or drying the alcohol/polyol-treated, cross-linked tissue, sterilizing the dried tissue by exposure to ethylene oxide or peracetic acid, and storing the sterilized tissue in a dry, ambient environment. The treated tissue may be a tissue component for a bioprosthetic valve, a valve assembly for a bioprosthetic valve or a fully assembled bioprosthetic valve incorporating the tissue.

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