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公开(公告)号：US20170079789A1
公开(公告)日：2017-03-23
申请号：US15371384
申请日：2016-12-07
IPC分类号： A61F2/24
CPC分类号： A61F2/2409 , A61F2/2403 , A61F2/2412 , A61F2/2415 , A61F2/2418 , A61F2/2433 , A61F2/89 , A61F2220/0008 , A61F2220/0075 , A61F2230/0006 , A61F2230/0054 , A61F2230/0069
摘要： Prosthetic heart valves, which are collapsible to a relatively small circumferential size for less invasive delivery into a patient and which then re-expand to operating size at an implant site in the patient, include a collapsible/expandable stent-like supporting structure and various components of flexible, sheet-like material that are attached to the supporting structure. For example, these sheet-like other components may include prosthetic valve leaflets, layers of buffering material, cuff material, etc. Improved structures and techniques are provided for securing such other components to the stent-like supporting structure of the valve.
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公开(公告)号：US20160228243A1
公开(公告)日：2016-08-11
申请号：US15098672
申请日：2016-04-14
IPC分类号： A61F2/24
CPC分类号： A61F2/2409 , A61F2/2403 , A61F2/2412 , A61F2/2415 , A61F2/2418 , A61F2/2433 , A61F2/89 , A61F2220/0008 , A61F2220/0075 , A61F2230/0006 , A61F2230/0054 , A61F2230/0069
摘要： A prosthetic heart valve includes a balloon-expandable stent including a plurality of struts and a plurality of commissure posts, each commissure post containing an elongated slot. A plurality of leaflets is made from pericardial tissue and includes flaps. An intermediate polymer sheet is disposed between the stent and the plurality of leaflets. At least one reinforcing polymer core is attached to at least one leaflet and the intermediate polymer sheet using stitches that loop around an end of the at least one leaflet. A plurality of patches covers the elongated slots of the commissure posts, the flaps of the leaflets being attached to the patches. A cuff contacts an exterior of the stent, the cuff and the intermediate polymer sheet sutured to one another so as to cover an axial end of the stent.
摘要翻译： 假体心脏瓣膜包括球囊扩张支架，其包括多个支柱和多个连合柱，每个连合柱包含细长槽。 多个传单由心包组织制成，包括襟翼。 中间聚合物片材设置在支架和多个传单之间。 至少一个增强聚合物芯使用围绕所述至少一个单张的末端环绕的针迹连接到至少一个小叶和中间聚合物片。 多个贴片覆盖连接柱的细长槽，传单的翼片附着到贴片上。 袖带接触支架的外部，袖带和中间聚合物片材彼此缝合以覆盖支架的轴向端部。
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公开(公告)号：US09345571B1
公开(公告)日：2016-05-24
申请号：US14954367
申请日：2015-11-30
CPC分类号： A61F2/2409 , A61F2/2403 , A61F2/2412 , A61F2/2415 , A61F2/2418 , A61F2/2433 , A61F2/89 , A61F2220/0008 , A61F2220/0075 , A61F2230/0006 , A61F2230/0054 , A61F2230/0069
摘要： Prosthetic heart valves, which are collapsible to a relatively small circumferential size for less invasive delivery into a patient and which then re-expand to operating size at an implant site in the patient, include a collapsible/expandable stent-like supporting structure and various components of flexible, sheet-like material that are attached to the supporting structure. For example, these sheet-like other components may include prosthetic valve leaflets, layers of buffering material, cuff material, etc. Improved structures and techniques are provided for securing such other components to the stent-like supporting structure of the valve.
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公开(公告)号：US09549815B2
公开(公告)日：2017-01-24
申请号：US15098672
申请日：2016-04-14
CPC分类号： A61F2/2409 , A61F2/2403 , A61F2/2412 , A61F2/2415 , A61F2/2418 , A61F2/2433 , A61F2/89 , A61F2220/0008 , A61F2220/0075 , A61F2230/0006 , A61F2230/0054 , A61F2230/0069
摘要： A prosthetic heart valve includes a balloon-expandable stent including a plurality of struts and a plurality of commissure posts, each commissure post containing an elongated slot. A plurality of leaflets is made from pericardial tissue and includes flaps. An intermediate polymer sheet is disposed between the stent and the plurality of leaflets. At least one reinforcing polymer core is attached to at least one leaflet and the intermediate polymer sheet using stitches that loop around an end of the at least one leaflet. A plurality of patches covers the elongated slots of the commissure posts, the flaps of the leaflets being attached to the patches. A cuff contacts an exterior of the stent, the cuff and the intermediate polymer sheet sutured to one another so as to cover an axial end of the stent.
摘要翻译： 假体心脏瓣膜包括球囊扩张支架，其包括多个支柱和多个连合柱，每个连合柱包含细长槽。 多个传单由心包组织制成，包括襟翼。 中间聚合物片材设置在支架和多个传单之间。 至少一个增强聚合物芯使用围绕所述至少一个单张的末端环绕的针迹连接到至少一个小叶和中间聚合物片。 多个贴片覆盖连接柱的细长槽，传单的翼片附着到贴片上。 袖带接触支架的外部，袖带和中间聚合物片材彼此缝合以覆盖支架的轴向端部。
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公开(公告)号：US20160213466A1
公开(公告)日：2016-07-28
申请号：US15088535
申请日：2016-04-01
IPC分类号： A61F2/24
CPC分类号： A61F2/2409 , A61F2/2403 , A61F2/2412 , A61F2/2415 , A61F2/2418 , A61F2/2433 , A61F2/89 , A61F2220/0008 , A61F2220/0075 , A61F2230/0006 , A61F2230/0054 , A61F2230/0069
摘要： A prosthetic heart valve includes an annularly collapsible and re-expandable supporting structure extending between an inflow end and an outflow end and including a plurality of struts and a plurality of posts, each post having an elongated opening, a plurality of leaflets disposed inside the supporting structure and operative to allow flow in a first direction from the inflow end to the outflow end and to substantially block flow in an opposite direction from the outflow end to the inflow end, each of the plurality of leaflets including flaps, and a first patch covering the opening of a first post, the first patch being attached to a first flap of a first leaflet.
摘要翻译： 假体心脏瓣膜包括在流入端和流出端之间延伸并且包括多个支柱和多个柱的环形可折叠和可重新扩张的支撑结构，每个柱具有细长开口，设置在支撑件内的多个小叶 结构并且可操作以允许沿着从流入端到流出端的第一方向流动，并且基本上阻止从流出端到流入端的相反方向的流动，所述多个传单中的每一个包括襟翼，以及第一贴片覆盖 所述第一贴片的开口部，所述第一贴片附接到第一传单的第一折片。
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公开(公告)号：US20150081013A1
公开(公告)日：2015-03-19
申请号：US14334059
申请日：2014-07-17
IPC分类号： A61F2/24
CPC分类号： A61F2/2409 , A61F2/2403 , A61F2/2412 , A61F2/2415 , A61F2/2418 , A61F2/2433 , A61F2/89 , A61F2220/0008 , A61F2220/0075 , A61F2230/0006 , A61F2230/0054 , A61F2230/0069
摘要： Prosthetic heart valves, which are collapsible to a relatively small circumferential size for less invasive delivery into a patient and which then re-expand to operating size at an implant site in the patient, include a collapsible/expandable stent-like supporting structure and various components of flexible, sheet-like material that are attached to the supporting structure. For example, these sheet-like other components may include prosthetic valve leaflets, layers of buffering material, cuff material, etc. Improved structures and techniques are provided for securing such other components to the stent-like supporting structure of the valve.
摘要翻译： 假体心脏瓣膜可折叠到相对较小的圆周尺寸以便较少侵入性地输送到患者体内，然后在患者的植入部位再扩张至操作尺寸，包括可折叠/可扩张的支架状支撑结构和各种部件 柔性的片状材料，其附接到支撑结构。 例如，这些片状的其他部件可以包括假体瓣膜小叶，缓冲材料层，袖带材料等。提供了改进的结构和技术，用于将这些其它部件固定到瓣膜的支架状支撑结构上。
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公开(公告)号：US09545307B2
公开(公告)日：2017-01-17
申请号：US15079244
申请日：2016-03-24
CPC分类号： A61F2/2409 , A61F2/2403 , A61F2/2412 , A61F2/2415 , A61F2/2418 , A61F2/2433 , A61F2/89 , A61F2220/0008 , A61F2220/0075 , A61F2230/0006 , A61F2230/0054 , A61F2230/0069
摘要： A prosthetic heart valve includes an annularly collapsible and re-expandable supporting structure extending between an inflow end and an outflow end and including a plurality of struts, the inflow end having an inflow edge, a plurality of leaflets disposed inside the supporting structure and operative to allow flow in an antegrade direction from the inflow end to the outflow end but to substantially block flow in a retrograde direction from the outflow end to the inflow end, a first material disposed on a luminal surface of the supporting structure adjacent the inflow end, and a second material disposed on an abluminal surface of the supporting structure adjacent the inflow end, the first material and the second material being secured to selected struts of the supporting structure, and separately secured to each other adjacent the inflow edge.
摘要翻译： 假体心脏瓣膜包括在流入端和流出端之间延伸并且包括多个支柱的环形可折叠和可重新扩张的支撑结构，所述流入端具有流入边缘，多个传单设置在支撑结构内并且可操作以 允许从流入端到流出端的顺流方向流动，但是基本上阻挡从流出端到流入端的逆行方向的流动，设置在与流入端相邻的支撑结构的腔表面上的第一材料，以及 第二材料，其布置在邻近流入端的支撑结构的外腔表面上，第一材料和第二材料固定到支撑结构的选定的支柱上，并且在流入边缘附近彼此独立地固定。
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公开(公告)号：US20160213468A1
公开(公告)日：2016-07-28
申请号：US15088524
申请日：2016-04-01
IPC分类号： A61F2/24
CPC分类号： A61F2/2409 , A61F2/2403 , A61F2/2412 , A61F2/2415 , A61F2/2418 , A61F2/2433 , A61F2/89 , A61F2220/0008 , A61F2220/0075 , A61F2230/0006 , A61F2230/0054 , A61F2230/0069
摘要： A prosthetic heart valve includes an annularly collapsible and re-expandable supporting structure extending between an inflow end and an outflow end and including a plurality of struts, a plurality of leaflets disposed inside the supporting structure and operative to allow flow in a first direction from the inflow end to the outflow end and to substantially block flow in an opposite direction from the outflow end to the inflow end, a sheet circumferentially disposed on an inner surface of the supporting structure and coupled to the supporting structure, a reinforcing core coupled to at least one of the plurality of leaflets, and a plurality of stitches coupling the reinforcing core to the sheet and one of the plurality of leaflets.
摘要翻译： 假体心脏瓣膜包括在流入端和流出端之间延伸并包括多个支柱的环形可折叠和可重新扩张的支撑结构，多个小叶布置在支撑结构内部并且可操作以允许沿第一方向从 流入端到流出端并且基本上阻挡从流出端到流入端的相反方向的流动;周向地设置在支撑结构的内表面上并联接到支撑结构的片，至少与 多个传单中的一个，以及将加强芯连接到片材和多个传单中的一个的多个线圈。
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公开(公告)号：US20160074162A1
公开(公告)日：2016-03-17
申请号：US14948780
申请日：2015-11-23
IPC分类号： A61F2/24
CPC分类号： A61F2/2409 , A61F2/2403 , A61F2/2412 , A61F2/2415 , A61F2/2418 , A61F2/2433 , A61F2/89 , A61F2220/0008 , A61F2220/0075 , A61F2230/0006 , A61F2230/0054 , A61F2230/0069
摘要： Prosthetic heart valves, which are collapsible to a relatively small circumferential size for less invasive delivery into a patient and which then re-expand to operating size at an implant site in the patient, include a collapsible/expandable stent-like supporting structure and various components of flexible, sheet-like material that are attached to the supporting structure. For example, these sheet-like other components may include prosthetic valve leaflets, layers of buffering material, cuff material, etc. Improved structures and techniques are provided for securing such other components to the stent-like supporting structure of the valve.
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公开(公告)号：US08845721B2
公开(公告)日：2014-09-30
申请号：US13848466
申请日：2013-03-21
IPC分类号： A61F2/24
CPC分类号： A61F2/2409 , A61F2/2403 , A61F2/2412 , A61F2/2415 , A61F2/2418 , A61F2/2433 , A61F2/89 , A61F2220/0008 , A61F2220/0075 , A61F2230/0006 , A61F2230/0054 , A61F2230/0069
摘要： A prosthetic heart valve includes a collapsible and expandable stent having a proximal end, a distal end, an annulus section adjacent the proximal end and an aortic section adjacent the distal end, a plurality of commissure features disposed on the stent, and a collapsible and expandable valve assembly, the valve assembly including a plurality of leaflets connected to the plurality of commissure features. Each commissure feature includes a body having a proximal end a distal end, and a plurality of eyelets arranged in at least two rows and at least two columns for attaching the body to the plurality of leaflets.
摘要翻译： 假体心脏瓣膜包括可折叠和可扩张的支架，其具有近端，远端，邻近近端的环形部分和邻近远端的主动脉部分，布置在支架上的多个合缝特征，以及可折叠和可扩张的 阀组件，阀组件包括连接到多个连合件的多个传单。 每个连合特征包括具有近端远端的主体和布置成至少两排和至少两列的多个孔眼，用于将主体附接到多个传单。
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