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公开(公告)号:US11383986B2
公开(公告)日:2022-07-12
申请号:US17416244
申请日:2019-12-20
发明人: Indu Bhushan , Vinay Rao , Rakshith Shetty
摘要: The present disclosure relates to a method for chemically modifying particles of a bicarbonate salt in a co-rotating twin-screw extruder and chemically modified bicarbonate particles prepared therefrom. The present disclosure also relates to a method for controlling an amount of carbonate salt formed during chemical modification of bicarbonate salt particles.
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公开(公告)号:US11219594B2
公开(公告)日:2022-01-11
申请号:US15781090
申请日:2016-12-12
发明人: Indu Bhushan , Vijay Kulkarni , Rakshith Shetty
摘要: The present invention relates to effervescent compositions of Metformin and optionally other anti-diabetic agents and processes for preparation thereof. More particularly provides an effervescent composition comprising Metformin, an acid and a base such that the composition is free of affirmatively added binders and granulating solvents. The effervescent composition of the present invention has retained carbon dioxide content of at least 90% of the input blend.
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