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公开(公告)号：US20080294035A1
公开(公告)日：2008-11-27
申请号：US12124681
申请日：2008-05-21
CPC分类号： A61B5/055 , A61B5/0515 , G06T7/60
摘要： A system and method of evaluating the effectiveness of antiangionetic therapy is described. A patient or test animal is treated with an antiangionetic substance. Magnetic resonance imaging data is obtained prior to and subsequent to the treatment. The parameters of the imaging process are configured so that, by administering a intravascular contrast agent, the relative size of the microvascular and the total vascular volumes in a region of interest may be obtained, so as to form a vascular size index. The value of the vascular size index and other pharmacokinetic data obtained by the administration of a diffusible contrast agent are used to assess the efficacy of the treatment or the antiangionetic substance being studied.
摘要翻译： 描述了评估抗血管治疗疗效的系统和方法。 患者或测试动物用抗血友病药物治疗。 在治疗之前和之后获得磁共振成像数据。 成像过程的参数被配置为使得通过施用血管内造影剂可以获得感兴趣区域中的微血管的相对大小和总血管体积，从而形成血管尺寸指数。 使用通过施用可扩散造影剂获得的血管尺寸指数和其他药代动力学数据的值来评估所研究的治疗或抗血小球药物的功效。
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公开(公告)号：US08195275B2
公开(公告)日：2012-06-05
申请号：US12124681
申请日：2008-05-21
CPC分类号： A61B5/055 , A61B5/0515 , G06T7/60
摘要： A system and method of evaluating the effectiveness of antiangionetic therapy is described. A patient or test animal is treated with an antiangionetic substance. Magnetic resonance imaging data is obtained prior to and subsequent to the treatment. The parameters of the imaging process are configured so that, by administering a intravascular contrast agent, the relative size of the microvascular and the total vascular volumes in a region of interest may be obtained, so as to form a vascular size index. The value of the vascular size index and other pharmacokinetic data obtained by the administration of a diffusible contrast agent are used to assess the efficacy of the treatment or the antiangionetic substance being studied.
摘要翻译： 描述了评估抗血管治疗疗效的系统和方法。 患者或测试动物用抗血友病药物治疗。 在治疗之前和之后获得磁共振成像数据。 成像过程的参数被配置为使得通过施用血管内造影剂可以获得感兴趣区域中的微血管的相对大小和总血管体积，从而形成血管尺寸指数。 使用通过施用可扩散造影剂获得的血管尺寸指数和其他药代动力学数据的值来评估所研究的治疗或抗血小球药物的功效。
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3.发明申请公开(公告)号：US20080139927A1
公开(公告)日：2008-06-12
申请号：US11794911
申请日：2006-01-10
IPC分类号： A61B5/055
CPC分类号： G01R33/34053 , A61B5/055 , G01R33/34084 , G01R33/5608
摘要： The present invention relates to an implantable chamber (1) with a connecting element (2), comprising a connecting sleeve (6) and a surrounding contact surface (7), an insert element (3), comprising an insert sleeve (8) and a surrounding abutment surface (9). The insert sleeve (8) is inserted into the connecting sleeve (6) of the connecting element (2). The implantable chamber (1) further comprises a cap (4) with a surrounding edge (11), the cap (4) partly covering the connecting element (2) and the insert element (3), leaving an opening (13) on one side. The implantable chamber (1) contains a passive resonance circuit (14) with an inductance and a capacitance, the passive resonance circuit (14) surrounding at least part of a cavity (15) inside the insert element (3).
摘要翻译： 本发明涉及具有连接元件（2）的可植入室（1），其包括连接套筒（6）和周围的接触表面（7），插入元件（3），其包括插入套筒（8）和 周围的邻接表面（9）。 插入套筒（8）插入到连接元件（2）的连接套筒（6）中。 植入式腔室（1）还包括具有周围边缘（11）的帽（4），帽部分（4）部分地覆盖连接元件（2）和插入元件（3），在其上形成开口（13） 侧。 可植入室（1）包含具有电感和电容的无源谐振电路（14），无源谐振电路（14）围绕插入元件（3）内的空腔（15）的至少一部分。
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