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公开(公告)号：US09970942B2
公开(公告)日：2018-05-15
申请号：US14342079
申请日：2012-09-04
IPC分类号： A61K39/00 , A61K39/35 , A61K39/36 , C12Q1/00 , C12Q1/40 , G01N33/00 , G01N24/00 , G01N1/00 , G01N33/68 , G01N30/72 , G01N30/88
CPC分类号： G01N33/6848 , G01N30/7233 , G01N2030/8831 , G01N2333/415 , G01N2333/4713 , G01N2333/4731 , G01N2333/77 , G01N2333/976 , G01N2800/24
摘要： Methods and systems for detecting allergens using mass spectrometry are provided herein. In some aspects, a sample can be screened for the presence or quantity of ovalbumin, lysozyme, casein (isoform S1 and S2), lactoglobulin, high and low glutens, wheat, rye, oats, barley, mustard, sesame, and various types of nuts including macadamia, pistachio, brazil, walnuts, peanuts and hazelnuts by detecting one or more peptides specific to the allergen of interest using selected MRM transitions.
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公开(公告)号：US20160025741A1
公开(公告)日：2016-01-28
申请号：US14342079
申请日：2012-09-02
IPC分类号： G01N33/68
CPC分类号： G01N33/6848 , G01N30/7233 , G01N2030/8831 , G01N2333/415 , G01N2333/4713 , G01N2333/4731 , G01N2333/77 , G01N2333/976 , G01N2800/24
摘要： Methods and systems for detecting allergens using mass spectrometry are provided herein. In some aspects, a sample can be screened for the presence or quantity of ovalbumin, lysozyme, casein (isoform S1 and S2), lactoglobulin, high and low glutens, wheat, rye, oats, barley, mustard, sesame, and various types of nuts including macadamia, pistachio, brazil, walnuts, peanuts and hazelnuts by detecting one or more peptides specific to the allergen of interest using selected MRM transitions.
摘要翻译： 本文提供了使用质谱检测过敏原的方法和系统。 在一些方面，可以筛选样品的卵白蛋白，溶菌酶，酪蛋白（同种型S1和S2），乳球蛋白，高低谷蛋白，小麦，黑麦，燕麦，大麦，芥末，芝麻和各种类型的 通过使用选择的MRM转变检测感兴趣的变应原特异性的一种或多种肽，包括澳洲坚果，开心果，巴西，核桃，花生和榛子。
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