Tablets containing heat sensitive materials and method for forming thereof
    2.
    发明授权
    Tablets containing heat sensitive materials and method for forming thereof 有权
    含有热敏材料的片剂及其形成方法

    公开(公告)号:US06627220B2

    公开(公告)日:2003-09-30

    申请号:US09904807

    申请日:2001-07-13

    IPC分类号: A61K914

    摘要: The present invention provides a process and apparatus for preserving the potency of a tableted heat sensitive ingredient. The process includes the steps of forming the ingredient into a tablet and cooling the tablet for a sufficient time and at a sufficiently low temperature to decrease the heat degradation of the ingredient. The process may be carried out in any number of tablet cooling apparatus, including a conduit forming a passageway for receiving tablets from the tablet press. A coolant inlet is connected to the conduit for supplying coolant into the passageway and into contact with the tablets.

    摘要翻译: 本发明提供了一种用于保持压片热敏成分的效力的方法和装置。 该方法包括将成分形成片剂并将片剂冷却足够的时间并在足够低的温度下降低成分的热降解的步骤。 该方法可以在任何数量的片剂冷却装置中进行,包括形成用于从压片机接收片剂的通道的导管。 冷却剂入口连接到导管,用于将冷却剂供应到通道中并与片剂接触。

    Method and system for assembling and utilizing components in component object systems
    3.
    发明授权
    Method and system for assembling and utilizing components in component object systems 失效
    组件和组件对象系统中组件和组件的使用方法和系统

    公开(公告)号:US06230309B1

    公开(公告)日:2001-05-08

    申请号:US08845583

    申请日:1997-04-25

    IPC分类号: G06F945

    CPC分类号: G06F8/36

    摘要: A design tool for assembling component objects to form an object-based computer system application includes a declarative user input interface mechanism and a design engine. The declarative user input interface mechanism provides an input structure for the input of user declarations specifying operative interactions between component objects. The design engine automatically generates, in response to input user declarations, an application design definition modelling an application infrastructure for managing component object interactions. An application design definition can reference a number of application view definitions, each having a number of fields, each field having associated therewith an application view field definition. An operation usage definition defines an effect a component object operation has on one or more of the application view definitions in response to user input declarations. An event definition defines an operation usage triggered by an application view definition event in response to input user declarations. The design engine automatically generates, in response to input user declarations, a match between an application view field definition and a parameter of an associated component object operation. A runtime tool includes an application engine which is responsive to an application design definition and is operative at runtime automatically to create application view instances from respective application view definitions for managing runtime component object interactions for the application.

    摘要翻译: 用于组装组件对象以形成基于对象的计算机系统应用程序的设计工具包括声明式用户输入接口机制和设计引擎。 声明式用户输入接口机制提供输入结构,用于输入用户声明,指定组件对象之间的操作性交互。 设计引擎自动生成响应于输入用户声明的应用程序设计定义,建模应用程序基础结构以管理组件对象交互。 应用程序设计定义可以引用多个应用程序视图定义,每个应用程序视图定义具有多个字段,每个字段都与应用程序视图字段定义相关联。 操作使用定义定义组件对象操作对响应于用户输入声明的一个或多个应用程序视图定义的影响。 事件定义定义响应于输入用户声明的应用程序视图定义事件触发的操作使用。 设计引擎响应于输入用户声明自动生成应用程序视图字段定义和相关组件对象操作的参数之间的匹配。 运行时工具包括响应于应用程序设计定义的应用程序引擎,并在运行时自动运行,以从相应的应用程序视图定义创建应用程序视图实例,以管理应用程序的运行时组件对象交互。

    Methods and apparatus for preparing high-dimensional combinatorial experiments
    5.
    发明授权
    Methods and apparatus for preparing high-dimensional combinatorial experiments 失效
    制备高维组合实验的方法和装置

    公开(公告)号:US07882053B2

    公开(公告)日:2011-02-01

    申请号:US11348873

    申请日:2006-02-06

    IPC分类号: G06N5/00

    摘要: Computer-implemented methods, systems and apparatus, including computer program apparatus, provide techniques for designing a set of experiments to be performed with a set of resources. A plurality of experimental configurations are generated based on a set of parameters describing factors to be varied in the experiments and a set of constraints representing limitations on operations that can be performed with the set of resources. A set of experiments is defined based on a selected configuration. The constraints can be represented as patterns defining an application of a parameter to a set of one or more points of an experimental lattice.

    摘要翻译: 包括计算机程序设备在内的计算机实现的方法,系统和装置提供了用于设计要用一组资源执行的一组实验的技术。 基于描述在实验中变化的因素的一组参数生成多个实验配置,以及一组表示可以用该组资源执行的操作的限制。 基于所选配置定义一组实验。 约束可以表示为将参数应用于实验网格的一个或多个点的集合的模式。

    Graphic design of combinatorial material libraries
    6.
    发明授权
    Graphic design of combinatorial material libraries 失效
    组合材料库的平面设计

    公开(公告)号:US07199809B1

    公开(公告)日:2007-04-03

    申请号:US09420334

    申请日:1999-10-18

    IPC分类号: G06F3/00 G06F19/00

    CPC分类号: C40B50/02

    摘要: Computer-implemented methods, programs and apparatus for generating a library design for a combinatorial library of materials. A library design includes a set of sources representing components to be used in preparing the combinatorial library, destinations replying arrangements of cells and mappings, defining one or more distribution patterns for assigning components to cells in the destination arrangement or arrangements. Mappings include gradients and sets of user-defined equations, and are used to calculate the amount of on components to be assigned to a cell or cells in an arrangement. A library design can also include one or more process parameters defined to vary over time or across a plurality of destination cells. The invention outputs a data file defining the library design, including electronic data representing the sources, the destinations and the mapping, in a format suitable for implementing manually or using automated material handling apparatus.

    摘要翻译: 用于生成材料组合库的图书馆设计的计算机实现的方法,程序和装置。 图书馆设计包括一组来源,表示将用于准备组合图书馆的组件,答复单元布置和映射的目的地,定义用于将组件分配给目的地布置或布置中的单元的一个或多个分配模式。 映射包括梯度和用户定义方程组,并用于计算要分配给单元格或单元格的组件的数量。 库设计还可以包括一个或多个过程参数,其定义为随时间变化或跨多个目的地小区而变化。 本发明以适合手动实现或使用自动化材料处理装置的格式输出定义库设计的数据文件,包括表示源,目的地和映射的电子数据。

    Methods and apparatus for preparing high-dimensional combinatorial experiments
    7.
    发明授权
    Methods and apparatus for preparing high-dimensional combinatorial experiments 失效
    制备高维组合实验的方法和装置

    公开(公告)号:US06996550B2

    公开(公告)日:2006-02-07

    申请号:US10024649

    申请日:2001-12-17

    IPC分类号: G06F15/18

    摘要: Computer-implemented methods, systems and apparatus, including computer program apparatus, provide techniques for designing a set of experiments to be performed with a set of resources. A plurality of experimental configurations are generated based on a set of parameters describing factors to be varied in the experiments and a set of constraints representing limitations on operations that can be performed with the set of resources. A set of experiments is defined based on a selected configuration. The constraints can be represented as patterns defining an application of a parameter to a set of one or more points of an experimental lattice.

    摘要翻译: 包括计算机程序设备在内的计算机实现的方法,系统和装置提供了用于设计要用一组资源执行的一组实验的技术。 基于描述在实验中变化的因素的一组参数生成多个实验配置,以及一组表示可以用该组资源执行的操作的限制。 基于所选配置定义一组实验。 约束可以表示为将参数应用于实验网格的一个或多个点的集合的模式。

    Method and system for assembling and utilizing components in component object systems
    8.
    发明授权
    Method and system for assembling and utilizing components in component object systems 有权
    组件和组件对象系统中组件和组件的使用方法和系统

    公开(公告)号:US06957417B2

    公开(公告)日:2005-10-18

    申请号:US09800597

    申请日:2001-03-06

    CPC分类号: G06F8/36

    摘要: A design tool for assembling component objects to form an object-based computer system application includes a declarative user input interface mechanism and a design engine. The declarative user input interface mechanism provides an input structure for the input of user declarations specifying operative interactions between component objects. The design engine automatically generates, in response to input user declarations, an application design definition modeling an application infrastructure for managing component object interactions. The design engine automatically generates, in response to input user declarations, a match between an application view field definition and a parameter of an associated component object operations. A runtime tool includes an application engine which is responsive to an application design definition and is operative at runtime automatically to create application view instances from respective application view definitions for managing runtime component object interactions for the applications.

    摘要翻译: 用于组装组件对象以形成基于对象的计算机系统应用程序的设计工具包括声明式用户输入接口机制和设计引擎。 声明式用户输入接口机制提供输入结构,用于输入用户声明,指定组件对象之间的操作性交互。 设计引擎自动生成响应于输入用户声明的应用程序设计定义,建模应用程序基础结构以管理组件对象交互。 设计引擎响应于输入用户声明自动生成应用程序视图字段定义和关联组件对象操作的参数之间的匹配。 运行时工具包括响应于应用程序设计定义的应用程序引擎,并在运行时自动运行,以从相应的应用程序视图定义创建应用程序视图实例,以管理应用程序的运行时组件对象交互。

    Recognition procedure and an apparatus for carrying out the recognition
procedure
    9.
    发明授权
    Recognition procedure and an apparatus for carrying out the recognition procedure 失效
    识别程序和执行认可程序的手段

    公开(公告)号:US5056147A

    公开(公告)日:1991-10-08

    申请号:US520195

    申请日:1990-05-09

    摘要: Apparatus and methods are disclosed for recognizing patterns, i.e., comparing a stored pattern with a pattern to be measured. The apparatus is taught a stored or reference pattern by assigning a first binary value to each of a plurality of addressable data stores at locations selected by applying respective sets of values to the stores, the values representing characteristics of the stored pattern. A second binary value is assigned to all locations not selected. The pattern to be measured has sets of values representing characteristics thereof applied to respective addresses of the addressable data stores. The contents of the selected addresses are read and the binary values from the selected addresses are applied to a network capable of providing an output signal representing a selected binary value only when the first binary value is read from all selected locations. The output signal represents the result of the measurement and may provide a measure of the closeness of the stored and observed patterns.