公开(公告)号：US20120076831A1

公开(公告)日：2012-03-29

申请号：US13144918

申请日：2010-01-20

申请人： Stephen Miller ,  Russell L. Bromley ,  Michael A. Pleiss ,  Daniel Getts ,  Aaron Martin

发明人： Stephen Miller ,  Russell L. Bromley ,  Michael A. Pleiss ,  Daniel Getts ,  Aaron Martin

IPC分类号： A61K39/00 ,  A61P37/02 ,  A61P29/00 ,  A61P11/06 ,  A61P25/00 ,  A61P3/10 ,  A61K9/14 ,  A61P37/08 ,  B82Y5/00

CPC分类号： A61K39/0008 ,  A61K9/127 ,  A61K47/58 ,  A61K47/593 ,  A61K47/595 ,  A61K47/6911 ,  A61K47/6915 ,  A61K47/6921 ,  A61K2039/55555 ,  A61K2039/6093

摘要： The present invention utilizes carrier particles to present antigen peptides and proteins to the immune system in such a way as to induce antigen specific tolerance. The carrier particle is designed in order to trigger an immune tolerance effect. The invention is useful for treatment of immune related disorders such as autoimmune disease, transplant rejection and allergic reactions.

摘要翻译： 本发明利用载体颗粒以抗原特异性耐受性的方式将抗原肽和蛋白质提供给免疫系统。 设计载体颗粒以引发免疫耐受效应。 本发明可用于治疗免疫相关疾病，例如自身免疫性疾病，移植排斥反应和过敏反应。

公开(公告)号：US5704484A

公开(公告)日：1998-01-06

申请号：US684316

申请日：1996-07-18

申请人： Thomas L. Spinks ,  Russell L. Bromley ,  James T. Przybytek

发明人： Thomas L. Spinks ,  Russell L. Bromley ,  James T. Przybytek

IPC分类号： B65D23/00 ,  B65D23/08 ,  B65D23/10 ,  B65D25/20 ,  B65D25/28 ,  B65D21/00

CPC分类号： B65D23/10 ,  B65D23/0885

摘要： A protective bottle jacket for transporting a container, bottle or the like is provided. The protective jacket has a bottom portion having a base and walls projecting upwardly from the base for receiving and protecting the bottom portion of the container and a top portion having walls for covering the top portion of the container. The protective jacket has means for selectively and releasably interlocking the bottom and top portions together. The interlocking means comprises a male member disposed on one of the bottom and top portions and a passage disposed on the other of the bottom and top portions for slidably receiving the male member between an unlocked and locked position in response to rotation of the top and bottom jacket portions, wherein the passage lockably receives the male member and attaches the top and bottom portions together in the locked position and wherein the male member does not lockably engage the passage in the unlocked position. The protective jacket also has a handle assembly for transporting the jacket and bottle. The handle assembly has top and bottom handle portions attached to the top and bottom portions of the jacket respectively, such that the top and bottom handle portions operatively engage each other only when the interlocking means is in the locked position.

摘要翻译： 提供用于运输容器，瓶子等的保护性瓶子夹套。 保护套具有底部，底部具有从底部向上突出的壁，用于接收和保护容器的底部，顶部具有用于覆盖容器顶部的壁。 保护套具有用于选择性地和可释放地将底部和顶部互锁在一起的装置。 互锁装置包括设置在底部和顶部中的一个上的阳构件和设置在另一个底部和顶部上的通道，用于响应于顶部和底部的旋转可滑动地接收阳构件在解锁位置和锁定位置之间 护套部分，其中所述通道可锁定地接纳所述阳构件并将所述顶部和底部部分在一起锁定在所述锁定位置，并且所述阳构件不可锁定地接合所述通道在所述解锁位置。 护套还具有用于运输夹克和瓶子的手柄组件。 手柄组件具有分别附接到护套的顶部和底部的顶部和底部手柄部分，使得仅当互锁装置处于锁定位置时，顶部和底部手柄部分可操作地接合。