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![Pyrrolo[2,1-F] [1,2,4] Triazin-4-Ylamines IGF-1R Kinase Inhibitors for the Treatment of Cancer and Other Hyperproliferative Diseases](/abs-image/US/2011/12/01/US20110294776A1/abs.jpg.150x150.jpg)
1.发明申请Pyrrolo[2,1-F] [1,2,4] Triazin-4-Ylamines IGF-1R Kinase Inhibitors for the Treatment of Cancer and Other Hyperproliferative Diseases 失效吡咯并[2,1-F] [1,2,4]三嗪-4-基胺IGF-1R激酶抑制剂治疗癌症和其他过度增生性疾病公开(公告)号：US20110294776A1
公开(公告)日：2011-12-01
申请号：US12084411
申请日：2006-11-02
申请人： Stephen O'Connor , Jacques Dumas , Wendy Lee , Julie Dixon , David Cantin , David Gunn , Jennifer Burke , Barton Phillips , Derek Lowe , Tatiana Shelekhin , Gan Wang , Xin Ma , Shihong Ying , Andrea McClure , Furahi Achebe , Mario Lobell , Frederick Ehrgott , Christiana Iwuagwu , Kyle Parcella
发明人： Stephen O'Connor , Jacques Dumas , Wendy Lee , Julie Dixon , David Cantin , David Gunn , Jennifer Burke , Barton Phillips , Derek Lowe , Tatiana Shelekhin , Gan Wang , Xin Ma , Shihong Ying , Andrea McClure , Furahi Achebe , Mario Lobell , Frederick Ehrgott , Christiana Iwuagwu , Kyle Parcella
IPC分类号： A61K31/53 , C07D498/04 , A61P35/00 , A61K31/5383 , A61K31/541 , A61K31/55 , C07D487/04 , A61K31/5377
CPC分类号： C07D487/04
摘要： This invention relates to novel compounds of formula (I). Formula (I) in which the variable groups are as defined in the specification and claims, to pharmaceutical compositions containing them, and to a method of treatment using them for treatment of cancer.
摘要翻译： 本发明涉及新的式（I）化合物。 式（I）其中可变基团如说明书和权利要求中所定义，含有它们的药物组合物，以及使用它们治疗癌症的方法。
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![Pyrrolo[2,1-f][1,2,4]triazin-4-ylamines IGF-1R kinase inhibitors for the treatment of cancer and other hyperproliferative diseases](/abs-image/US/2013/04/30/US08431695B2/abs.jpg.150x150.jpg)
2.发明授权Pyrrolo[2,1-f][1,2,4]triazin-4-ylamines IGF-1R kinase inhibitors for the treatment of cancer and other hyperproliferative diseases 失效吡咯并[2,1-f] [1,2,4]三嗪-4-基胺治疗癌症和其他过度增生性疾病的IGF-1R激酶抑制剂公开(公告)号：US08431695B2
公开(公告)日：2013-04-30
申请号：US12084411
申请日：2006-11-02
申请人： Stephen O'Connor , Jacques Dumas , Wendy Lee , Julie Dixon , David Cantin , David Gunn , Jennifer Burke , Barton Phillips , Derek Lowe , Tatiana Shelekhin , Gan Wang , Xin Ma , Shihong Ying , Andrea McClure , Furahi Achebe , Mario Lobell , Frederick Ehrgott , Christiana Iwuagwu , Kyle Parcella
发明人： Stephen O'Connor , Jacques Dumas , Wendy Lee , Julie Dixon , David Cantin , David Gunn , Jennifer Burke , Barton Phillips , Derek Lowe , Tatiana Shelekhin , Gan Wang , Xin Ma , Shihong Ying , Andrea McClure , Furahi Achebe , Mario Lobell , Frederick Ehrgott , Christiana Iwuagwu , Kyle Parcella
IPC分类号： C07D487/04 , C07D413/02 , C07D417/02 , A61K31/53 , A61P35/00
CPC分类号： C07D487/04
摘要： This invention relates to novel compounds of formula (I). Formula (I) in which the variable groups are as defined in the specification and claims, to pharmaceutical compositions containing them, and to a method of treatment using them for treatment of cancer.
摘要翻译： 本发明涉及新的式（I）化合物。 式（I）其中可变基团如说明书和权利要求中所定义，含有它们的药物组合物，以及使用它们治疗癌症的方法。
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3.发明申请PYRIDONECARBOXAMIDE DERIVATIVES USEFUL IN TREATING HYPER-PROLIFERATIVE AND ANGIOGENESIS DISORDERS 审中-公开用于治疗高血压和血管发生疾病的吡啶甲酰甲胆碱衍生物公开(公告)号：US20090306103A1
公开(公告)日：2009-12-10
申请号：US12300751
申请日：2007-05-18
申请人： Stephen Boyer , David Cantin , Sidney X. Liang
发明人： Stephen Boyer , David Cantin , Sidney X. Liang
IPC分类号： A61K31/4709 , C07D401/12 , A61K31/517 , A61K31/4545 , A61K31/4375 , A61P35/00
CPC分类号： C07D401/12
摘要： Pyridonecarboxamide derivatives, pharmaceutical compositions which contain the same and methods for treating hyper-proliferative disorders and angiogenesis disorders using the same.
摘要翻译： 吡啶并甲酰胺衍生物，含有该化合物的药物组合物以及使用该组合物治疗高增殖性疾病和血管生成障碍的方法。
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