公开(公告)号：US20220381637A1

公开(公告)日：2022-12-01

申请号：US17804105

申请日：2022-05-26

Applicant: Stevanato Group S.P.A.

Inventor： Alberto Chillon ,  Barnaba Marchesini

IPC: G01L27/00

Abstract: A test unit for measuring internal pressure in a cylindrical glass container includes a support adapted for housing the cylindrical glass container during a test phase, defining a longitudinal axis; a piston for selectively exerting a predetermined axial force in a longitudinal direction substantially parallel to the longitudinal axis and for actuating a plunger movable along the longitudinal axis; at least one measuring sensor for measuring a change in diameter in a transverse direction to the longitudinal axis; a programmable control unit operatively connected to the measuring sensor and configured to correlate a diameter change measured by the measuring sensor in the presence of a predetermined axial force with reference internal pressure values to which the measured diameter change and the predetermined axial force correspond. Associated processes for measuring internal pressure in a cylindrical glass container are further disclosed.

公开(公告)号：US11714017B2

公开(公告)日：2023-08-01

申请号：US17804105

申请日：2022-05-26

Applicant: Stevanato Group S.P.A.

Inventor： Alberto Chillon ,  Barnaba Marchesini

IPC: G01L27/00 ,  G01N3/12 ,  G01L1/02 ,  A61M5/00

CPC classification number: G01L27/005 ,  G01N3/12 ,  A61M5/008 ,  A61M2205/70 ,  G01L1/02 ,  G01N2203/04 ,  G01N2203/0641

Abstract: A test unit for measuring internal pressure in a cylindrical glass container includes a support adapted for housing the cylindrical glass container during a test phase, defining a longitudinal axis; a piston for selectively exerting a predetermined axial force in a longitudinal direction substantially parallel to the longitudinal axis and for actuating a plunger movable along the longitudinal axis; at least one measuring sensor for measuring a change in diameter in a transverse direction to the longitudinal axis; a programmable control unit operatively connected to the measuring sensor and configured to correlate a diameter change measured by the measuring sensor in the presence of a predetermined axial force with reference internal pressure values to which the measured diameter change and the predetermined axial force correspond. Associated processes for measuring internal pressure in a cylindrical glass container are further disclosed.

公开(公告)号：US20240408312A1

公开(公告)日：2024-12-12

申请号：US18694903

申请日：2022-09-26

Applicant: Stevanato Group S.p.A.

Inventor： Alberto Chillon ,  Fabio Chinellato ,  Paolo Patri

IPC: A61M5/31 ,  C03C17/00 ,  C03C17/30

Abstract: A method of manufacturing a medical injection device comprising a glass cylinder having an inner surface coated with a coating layer, the cylinder being configured to receive a plunger with sliding engagement includes the steps of providing a coating composition comprising an amount equal to or greater than 92% by weight of polydimethylsiloxane having a kinematic viscosity at room temperature of from 11500 cSt (115 cm2/s) to 13500 cSt (135 cm2/s); heating the coating composition to a temperature of from 100° C. to 150° C.; and applying the coating composition heated to said temperature onto the inner surface of the cylinder so as to form a coating layer on the inner surface having an average thickness S, measured by means of optical reflectometry, of from 100 to 250 nm; wherein the coating layer of the inner surface of the cylinder has a thickness standard deviation, equal to or less than 90 nm.