公开(公告)号：US20080004638A1

公开(公告)日：2008-01-03

申请号：US11811392

申请日：2007-06-08

申请人： Steve Baker ,  Brett Carter ,  Stefan Kraemer ,  Clifton Alferness ,  John Adams

发明人： Steve Baker ,  Brett Carter ,  Stefan Kraemer ,  Clifton Alferness ,  John Adams

IPC分类号： A61B17/10 ,  A61B17/08

CPC分类号： A61B17/0401 ,  A61B17/0469 ,  A61B17/064 ,  A61B17/068 ,  A61B2017/00827 ,  A61B2017/0409 ,  A61B2017/0414 ,  A61B2017/0419

摘要： Tissue fasteners carried on a tissue piercing deployment wire fasten tissue layers of a mammalian body together. The fasteners include a first member, a second member, and a connecting member extending between the first and second members. The first and second members are substantially parallel to each other. The fasteners may be deployed in limited spaces and in various applications including the restoration of a gastroesophageal flap valve.

摘要翻译： 携带在组织穿刺部署线上的组织紧固件将哺乳动物身体的组织层紧固在一起。 紧固件包括第一构件，第二构件和在第一构件和第二构件之间延伸的连接构件。 第一和第二构件基本上彼此平行。 紧固件可以在有限的空间和各种应用中部署，包括恢复胃食管瓣阀。

公开(公告)号：US20050187565A1

公开(公告)日：2005-08-25

申请号：US10783717

申请日：2004-02-20

申请人： Steve Baker ,  Brett Carter ,  Stefan Kraemer ,  Clifton Alferness ,  John Adams

发明人： Steve Baker ,  Brett Carter ,  Stefan Kraemer ,  Clifton Alferness ,  John Adams

IPC分类号： A61B17/04 ,  A61B17/064 ,  A61B17/068 ,  A61B17/08 ,  A61B17/10

CPC分类号： A61B17/0401 ,  A61B17/0469 ,  A61B17/064 ,  A61B17/068 ,  A61B2017/00827 ,  A61B2017/0409 ,  A61B2017/0414 ,  A61B2017/0419

摘要： Tissue fasteners carried on a tissue piercing deployment wire fasten tissue layers of a mammalian body together. The fasteners include a first member, a second member, and a connecting member extending between the first and second members. The first and second members are substantially parallel to each other. The fasteners may be deployed in limited spaces and in various applications including the restoration of a gastroesophageal flap valve.

摘要翻译： 携带在组织穿刺部署线上的组织紧固件将哺乳动物身体的组织层紧固在一起。 紧固件包括第一构件，第二构件和在第一构件和第二构件之间延伸的连接构件。 第一和第二构件基本上彼此平行。 紧固件可以在有限的空间和各种应用中部署，包括恢复胃食管瓣阀。

公开(公告)号：US20060009792A1

公开(公告)日：2006-01-12

申请号：US11172363

申请日：2005-06-29

申请人： Steve Baker ,  Brett Carter ,  Stefan Kraemer ,  Clifton Alferness ,  John Adams ,  Raymond Wolniewicz

发明人： Steve Baker ,  Brett Carter ,  Stefan Kraemer ,  Clifton Alferness ,  John Adams ,  Raymond Wolniewicz

IPC分类号： A61B17/08

CPC分类号： A61B17/0401 ,  A61B17/0469 ,  A61B17/064 ,  A61B17/068 ,  A61B17/1114 ,  A61B2017/00827 ,  A61B2017/0409 ,  A61B2017/0414 ,  A61B2017/0419

摘要： A tissue fastener assembly delivers a fastener for deployment. The assembly includes a fastener including a first member, a second member, the first and second members having first and second ends, and a flexible connecting member fixed to each of the first and second members intermediate the first and second ends and extending between the first and second members. The first member has a longitudinal axis and a through channel along the axis. The assembly further includes a deployment wire slidingly received within the through channel of the first member that pierces into the tissue and guides the first member through the tissue, a guide structure defining a lumen that receives the fastener and deployment wire and guides the deployment wire and fastener to the tissue, and a fastener configuration structure that orientates the second member in a predetermined position relative to the first member within the lumen for dependable deployment.

公开(公告)号：US20060116697A1

公开(公告)日：2006-06-01

申请号：US11001666

申请日：2004-11-30

申请人： Brett Carter ,  John Adams ,  Stefan Kraemer ,  Steve Baker ,  John Bayne

发明人： Brett Carter ,  John Adams ,  Stefan Kraemer ,  Steve Baker ,  John Bayne

IPC分类号： A61B17/08

CPC分类号： A61B17/29 ,  A61B17/00234 ,  A61B17/0643 ,  A61B17/068 ,  A61B17/10 ,  A61B2017/003 ,  A61B2017/00827 ,  A61B2017/2905

摘要： A transoral gastroesophageal flap valve restoration device has sufficient flexibility and dimension to be passed through the mouth, throat, and esophagus of a patient into the patient's stomach. The device includes a first member and a second member hingedly coupled to the first member. The first and second members are configured to flex in a direction to follow the esophageal path into the stomach and to be substantially rigid when forming the restored gastroesophageal flap valve.

公开(公告)号：US20060190018A1

公开(公告)日：2006-08-24

申请号：US11061318

申请日：2005-02-18

申请人： Steve Baker ,  Brett Carter ,  Clifton Alferness

发明人： Steve Baker ,  Brett Carter ,  Clifton Alferness

IPC分类号： A61B17/08

CPC分类号： A61B17/08 ,  A61B17/29 ,  A61B2017/00349 ,  A61B2017/00827 ,  A61B2017/306

摘要： A transoral gastroesophageal flap valve restoration device includes a tissue gripper which is guidable by one of a first and second member. The first and second members form a tissue shaper carried on a longitudinal member that shapes stomach tissue into the flap of a restored gastroesophageal flap valve.

摘要翻译： 经口胃食管瓣瓣修复装置包括由第一和第二构件之一导引的组织夹持器。 第一和第二构件形成在纵向构件上承载的组织整形器，其将胃组织形成到恢复的胃食管瓣瓣的瓣中。

公开(公告)号：US20100094166A1

公开(公告)日：2010-04-15

申请号：US12287701

申请日：2008-10-10

申请人： Stefan Kraemer ,  Scott Harshman ,  Brett Carter ,  Richard Romley

发明人： Stefan Kraemer ,  Scott Harshman ,  Brett Carter ,  Richard Romley

IPC分类号： A61B10/02

CPC分类号： A61B10/0266 ,  A61B10/0283 ,  A61B10/04 ,  A61B2010/0225 ,  A61B2017/2908

摘要： A biopsy device is provided which has a plurality of sample chamber bodies with each body having a plurality of sample chambers. The sample chamber bodies are pivotally coupled to one another to permit the device to be steered and so that the device may conform somewhat to the shape of the esophagus.

摘要翻译： 提供一种活检装置，其具有多个样品室主体，每个主体具有多个样品室。 样品室主体彼此枢转地联接以允许装置被转向，使得该装置可以略微符合食道的形状。

公开(公告)号：US20070005082A1

公开(公告)日：2007-01-04

申请号：US11172427

申请日：2005-06-29

申请人： Stefan Kraemer ,  Brett Carter

发明人： Stefan Kraemer ,  Brett Carter

IPC分类号： A61B17/08

CPC分类号： A61B17/29 ,  A61B17/0401 ,  A61B17/0469 ,  A61B17/0644 ,  A61B17/10 ,  A61B17/1114 ,  A61B17/295 ,  A61B2017/003 ,  A61B2017/00349 ,  A61B2017/00367 ,  A61B2017/00827 ,  A61B2017/0409 ,  A61B2017/0419 ,  A61B2017/0647 ,  A61B2017/081 ,  A61B2217/005

摘要： Stomach tissue is manipulated to form, for example, a restored flap of a gastroesophageal flap valve. The manipulation includes gripping stomach tissue from within the stomach while the stomach is inflated to promote visualization and stabilization of the gripped stomach tissue. Once the stomach tissue is gripped, the stomach is deflated and pulled into a mold. The molded tissue is then fastened with at least one fastener. The stomach is inflated to a first pressure during visualization and then to a second higher pressure during the stomach tissue gripping.

摘要翻译： 操纵胃组织以形成例如胃食管瓣瓣的恢复的瓣。 所述操作包括在胃膨胀期间从胃内夹持胃组织以促进夹持的胃组织的可视化和稳定化。 一旦胃组织被夹紧，胃就被放气并拉入模具中。 然后用至少一个紧固件固定模制的组织。 在可视化期间将胃膨胀至第一压力，然后在胃组织夹持期间将其膨胀至第二较高压力。

公开(公告)号：US20070129738A1

公开(公告)日：2007-06-07

申请号：US11291500

申请日：2005-12-01

申请人： Stefan Kraemer ,  Brett Carter

发明人： Stefan Kraemer ,  Brett Carter

IPC分类号： A61B17/08

CPC分类号： A61B17/0401 ,  A61B17/0218 ,  A61B17/29 ,  A61B2017/003 ,  A61B2017/00349 ,  A61B2017/00827 ,  A61B2017/0409 ,  A61B2017/0419 ,  A61B2017/306

摘要： An apparatus enables concurrent restoration of a gastroesophageal valve and tightening of the lower esophageal sphincter. The apparatus comprises a longitudinal member having a distal end arranged to be received within a stomach, a tissue shaper at the distal end of the longitudinal member that forms a gastroesophageal valve from stomach tissue, and a tissue gatherer that gathers fundus tissue at or aboral to the gastroesophageal junction to reduce an esophageal opening into the stomach and tighten the lower esophageal sphincter. A fastener deployer then deploys at least one fastener pair to maintain both the restored gastroesophageal valve and the tightened lower esophageal sphincter.

摘要翻译： 一种装置能够同时恢复胃食管瓣并收紧下食道括约肌。 所述装置包括纵向构件，所述纵向构件具有设置成容纳在胃中的远端，在所述纵向构件的远端处的组织整形器，其形成来自胃组织的胃食管瓣，以及组织采集器，所述组织收集器将眼底组织收敛于或靠近 胃食管交界处减少食管开放进入胃部并收紧食管下端括约肌。 然后，紧固件部署器部署至少一个紧固件对，以保持恢复的胃食管瓣和收紧的下食道括约肌。

公开(公告)号：US20060116698A1

公开(公告)日：2006-06-01

申请号：US11001681

申请日：2004-11-30

申请人： John Bayne ,  Brett Carter ,  Steve Baker

发明人： John Bayne ,  Brett Carter ,  Steve Baker

IPC分类号： A61B17/08

CPC分类号： A61B17/10 ,  A61B17/064 ,  A61B17/0643 ,  A61B2017/00292 ,  A61B2017/003 ,  A61B2017/00827

摘要： A transoral gastroesophageal flap valve restoration device includes a single hinge coupling an arm to a body between which stomach tissue is folded to form a restored gastroesophageal flap valve. The device includes a drive mechanism that imparts reciprocal movement to the arm relative to the body. The drive mechanism includes a pulley of sufficient diameter to provide a mechanical advantage in imparting reciprocating movement of the arm relative to the body.

摘要翻译： 经口胃食管瓣瓣修复装置包括单个铰链，其将臂联接到身体之间，胃组织折叠在其之间以形成恢复的胃食管瓣瓣。 该装置包括驱动机构，其相对于身体向臂提供往复运动。 驱动机构包括足够直径的皮带轮，以提供臂相对于身体的往复运动的机械优点。

公开(公告)号：US20050187567A1

公开(公告)日：2005-08-25

申请号：US10949737

申请日：2004-09-23

申请人： Steve Baker ,  Brett Carter

发明人： Steve Baker ,  Brett Carter

IPC分类号： A61B17/04 ,  A61B17/064 ,  A61B17/068 ,  A61B17/08 ,  A61B17/10

CPC分类号： A61B17/0644 ,  A61B17/0401 ,  A61B17/0469 ,  A61B17/064 ,  A61B17/068 ,  A61B17/10 ,  A61B17/1285 ,  A61B2017/00827 ,  A61B2017/0409 ,  A61B2017/0414 ,  A61B2017/0419

摘要： Tissue fasteners carried on a tissue piercing deployment wire fasten tissue layers of a mammalian body together include a first member, a second member, and a connecting member extending between the first and second members. One of the first and second members has an elongated slot permitting fastener deployment while avoiding excessive tissue compression.

摘要翻译： 携带在组织刺穿展开线上的组织紧固件将哺乳动物身体的组织层紧固在一起包括第一构件，第二构件和在第一构件和第二构件之间延伸的连接构件。 第一和第二构件中的一个具有允许紧固件展开的细长狭缝，同时避免过度的组织压缩。