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1.发明授权Fibronectin type III domain based scaffold compositions, methods and uses 有权纤连蛋白III型结构域的支架组合物，方法和用途公开(公告)号：US09200059B2
公开(公告)日：2015-12-01
申请号：US13595484
申请日：2012-08-27
申请人： Steve Jacobs , Karyn O'Neil
发明人： Steve Jacobs , Karyn O'Neil
摘要： A protein scaffold based on a consensus sequence of fibronectin type III (FN3) proteins, such as the tenth FN3 repeat from human fibronectin (human Tenascin), including isolated nucleic acids that encode a protein scaffold, vectors, host cells, and methods of making and using thereof have applications in diagnostic and/or therapeutic compositions, methods and devices. In particular, protein scaffold molecules binding to IgG have been identified as useful for diagnostic and/or therapeutic applications.
摘要翻译： 基于纤连蛋白III（FN3）蛋白的共有序列的蛋白质支架，例如来自人纤连蛋白（人腱生蛋白）的第十FN3重复序列，包括编码蛋白质支架的分离的核酸，载体，宿主细胞和制备方法 并且其使用在诊断和/或治疗组合物，方法和装置中具有应用。 特别地，已经鉴定了结合IgG的蛋白质支架分子可用于诊断和/或治疗应用。
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公开(公告)号：US07249632B2
公开(公告)日：2007-07-31
申请号：US11371168
申请日：2006-03-07
申请人： Kip M. Robichaux , Terry P. Robichaux , Steve Jacobs , Bryan Clement , Murray Pellegrin , Kenneth G. Caillouet , Philip K. Watson
发明人： Kip M. Robichaux , Terry P. Robichaux , Steve Jacobs , Bryan Clement , Murray Pellegrin , Kenneth G. Caillouet , Philip K. Watson
IPC分类号： E21B33/16
CPC分类号： E21B21/00 , E21B17/05 , E21B21/02 , E21B33/05 , F16L27/087
摘要： For use with a top drive power unit supported for connection with a well string in a well bore to selectively impart longitudinal and/or rotational movement to the well string, a feeder for supplying a pumpable substance such as cement and the like from an external supply source to the interior of the well string in the well bore without first discharging it through the top drive power unit including a mandrel extending through a sleeve which is sealably and rotatably supported thereon for relative rotation between the sleeve and mandrel. The mandrel and sleeve have flow passages for communicating the pumpable substance from an external source to discharge through the sleeve and mandrel and into the interior of the well string below the top drive power unit. The unit can include a packing injection system, clamp, and novel packing configuration.
摘要翻译： 为了与支撑用于与井眼中的井串连接的顶部驱动动力单元一起使用以选择性地向井串施加纵向和/或旋转运动，用于从外部供应源供应可泵送物质例如水泥等的进料器 来源于井眼中的井串的内部，而不首先通过顶部驱动动力单元将其排出，该顶部驱动动力单元包括延伸穿过套筒的心轴，该心轴可密封地且可旋转地支撑在套筒和心轴之间进行相对旋转。 心轴和套管具有用于将可泵送物质从外部源连通的流动通道，以通过套筒和心轴排放到顶部驱动动力单元下方的井筒的内部。 该单元可以包括包装注射系统，夹具和新颖的包装配置。
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公开(公告)号：US20090223666A1
公开(公告)日：2009-09-10
申请号：US12400861
申请日：2009-03-10
申请人： Kip M. Robichaux , Terry P. Robichaux , Steve Jacobs , Bryan Clement , Murray Pellegrin , Kenneth G. Caillouet , Philip K. Watson
发明人： Kip M. Robichaux , Terry P. Robichaux , Steve Jacobs , Bryan Clement , Murray Pellegrin , Kenneth G. Caillouet , Philip K. Watson
CPC分类号： E21B21/00 , E21B17/05 , E21B21/02 , E21B33/05 , F16L27/087
摘要： For use with a top drive power unit supported for connection with a well string in a well bore to selectively impart longitudinal and/or rotational movement to the well string, a feeder for supplying a pumpable substance such as cement and the like from an external supply source to the interior of the well string in the well bore without first discharging it through the top drive power unit including a mandrel extending through a sleeve which is sealably and rotatably supported thereon for relative rotation between the sleeve and mandrel. The mandrel and sleeve have flow passages for communicating the pumpable substance from an external source to discharge through the sleeve and mandrel and into the interior of the well string below the top drive power unit. The unit can include a packing injection system, clamp, and novel packing configuration.
摘要翻译： 为了与支撑用于与井眼中的井串连接的顶部驱动动力单元一起使用以选择性地向井串施加纵向和/或旋转运动，用于从外部供应源供应可泵送物质例如水泥等的进料器 来源于井眼中的井串的内部，而不首先通过顶部驱动动力单元将其排出，该顶部驱动动力单元包括延伸穿过套筒的心轴，该心轴可密封地且可旋转地支撑在套筒和心轴之间进行相对旋转。 心轴和套管具有用于将可泵送物质从外部源连通的流动通道，以通过套筒和心轴排放到顶部驱动动力单元下方的井筒的内部。 该单元可以包括包装注射系统，夹具和新颖的包装配置。
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公开(公告)号：US20080179058A1
公开(公告)日：2008-07-31
申请号：US11831475
申请日：2007-07-31
申请人： Kip M. Robichaux , Terry P. Robichaux , Steve Jacobs , Bryan Clement , Murray Pellegrin , Kenneth G. Caillouet , Philip K. Watson
发明人： Kip M. Robichaux , Terry P. Robichaux , Steve Jacobs , Bryan Clement , Murray Pellegrin , Kenneth G. Caillouet , Philip K. Watson
IPC分类号： E21B33/068
CPC分类号： E21B21/00 , E21B17/05 , E21B21/02 , E21B33/05 , F16L27/087
摘要： For use with a top drive power unit supported for connection with a well string in a well bore to selectively impart longitudinal and/or rotational movement to the well string, a feeder for supplying a pumpable substance such as cement and the like from an external supply source to the interior of the well string in the well bore without first discharging it through the top drive power unit including a mandrel extending through a sleeve which is sealably and rotatably supported thereon for relative rotation between the sleeve and mandrel. The mandrel and sleeve have flow passages for communicating the pumpable substance from an external source to discharge through the sleeve and mandrel and into the interior of the well string below the top drive power unit. The unit can include a packing injection system, clamp, and novel packing configuration.
摘要翻译： 为了与支撑用于与井眼中的井串连接的顶部驱动动力单元一起使用以选择性地向井串施加纵向和/或旋转运动，用于从外部供应源供应可泵送物质例如水泥等的进料器 来源于井眼中的井串的内部，而不首先通过顶部驱动动力单元将其排出，该顶部驱动动力单元包括延伸穿过套筒的心轴，该心轴可密封地且可旋转地支撑在套筒和心轴之间进行相对旋转。 心轴和套管具有用于将可泵送物质从外部源连通的流动通道，以通过套筒和心轴排放到顶部驱动动力单元下方的井筒的内部。 该单元可以包括包装注射系统，夹具和新颖的包装配置。
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公开(公告)号：USD349465S
公开(公告)日：1994-08-09
申请号：US12299
申请日：1993-08-30
申请人： Steve Jacobs
设计人： Steve Jacobs
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公开(公告)号：US20060289154A1
公开(公告)日：2006-12-28
申请号：US11371168
申请日：2006-03-07
申请人： Kip Robichaux , Terry Robichaux , Steve Jacobs , Bryan Clement , Murray Pellegrin , Kenneth Caillouet , Philip Watson
发明人： Kip Robichaux , Terry Robichaux , Steve Jacobs , Bryan Clement , Murray Pellegrin , Kenneth Caillouet , Philip Watson
IPC分类号： E21B19/00
CPC分类号： E21B21/00 , E21B17/05 , E21B21/02 , E21B33/05 , F16L27/087
摘要： For use with a top drive power unit supported for connection with a well string in a well bore to selectively impart longitudinal and/or rotational movement to the well string, a feeder for supplying a pumpable substance such as cement and the like from an external supply source to the interior of the well string in the well bore without first discharging it through the top drive power unit including a mandrel extending through a sleeve which is sealably and rotatably supported thereon for relative rotation between the sleeve and mandrel. The mandrel and sleeve have flow passages for communicating the pumpable substance from an external source to discharge through the sleeve and mandrel and into the interior of the well string below the top drive power unit. The unit can include a packing injection system, clamp, and novel packing configuration.
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公开(公告)号：US20050034853A1
公开(公告)日：2005-02-17
申请号：US10658092
申请日：2003-09-09
申请人： Kip Robichaux , Terry Robichaux , Steve Jacobs , Bryan Clement , Murray Pellegrin , Kenneth Caillouet , Philip Watson
发明人： Kip Robichaux , Terry Robichaux , Steve Jacobs , Bryan Clement , Murray Pellegrin , Kenneth Caillouet , Philip Watson
IPC分类号： E21B20060101 , E21B17/05 , E21B19/00 , E21B21/00 , E21B21/02 , E21B33/05 , E21B33/16 , F16L27/093
CPC分类号： E21B21/00 , E21B17/05 , E21B21/02 , E21B33/05 , F16L27/087
摘要： For use with a top drive power unit supported for connection with a well string in a well bore to selectively impart longitudinal and/or rotational movement to the well string, a feeder for supplying a pumpable substance such as cement and the like from an external supply source to the interior of the well string in the well bore without first discharging it through the top drive power unit including a mandrel extending through a sleeve which is sealably and rotatably supported thereon for relative rotation between the sleeve and mandrel. The mandrel and sleeve have flow passages for communicating the pumpable substance from an external source to discharge through the sleeve and mandrel and into the interior of the well string below the top drive power unit. The unit can include a packing injection system, clamp, and novel packing configuration.
摘要翻译： 为了与支撑用于与井眼中的井串连接的顶部驱动动力单元一起使用以选择性地向井串施加纵向和/或旋转运动，用于从外部供应源供应可泵送物质例如水泥等的进料器 来源于井眼中的井串的内部，而不首先通过顶部驱动动力单元将其排出，该顶部驱动动力单元包括延伸穿过套筒的心轴，该心轴可密封地且可旋转地支撑在套筒和心轴之间进行相对旋转。 心轴和套管具有用于将可泵送物质从外部源连通的流动通道，以通过套筒和心轴排放到顶部驱动动力单元下方的井筒的内部。 该单元可以包括包装注射系统，夹具和新颖的包装配置。
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公开(公告)号：US07845408B2
公开(公告)日：2010-12-07
申请号：US12400861
申请日：2009-03-10
申请人： Kip M. Robichaux , Terry P. Robichaux , Steve Jacobs , Bryan Clement , Murray Pellegrin , Kenneth G. Caillouet , Philip K. Watson
发明人： Kip M. Robichaux , Terry P. Robichaux , Steve Jacobs , Bryan Clement , Murray Pellegrin , Kenneth G. Caillouet , Philip K. Watson
CPC分类号： E21B21/00 , E21B17/05 , E21B21/02 , E21B33/05 , F16L27/087
摘要： For use with a top drive power unit supported for connection with a well string in a well bore to selectively impart longitudinal and/or rotational movement to the well string, a feeder for supplying a pumpable substance such as cement and the like from an external supply source to the interior of the well string in the well bore without first discharging it through the top drive power unit including a mandrel extending through a sleeve which is sealably and rotatably supported thereon for relative rotation between the sleeve and mandrel. The mandrel and sleeve have flow passages for communicating the pumpable substance from an external source to discharge through the sleeve and mandrel and into the interior of the well string below the top drive power unit. The unit can include a packing injection system, clamp, and novel packing configuration.
摘要翻译： 为了与支撑用于与井眼中的井串连接的顶部驱动动力单元一起使用以选择性地向井串施加纵向和/或旋转运动，用于从外部供应源供应可泵送物质例如水泥等的进料器 来源于井眼中的井串的内部，而不首先通过顶部驱动动力单元将其排出，该顶部驱动动力单元包括延伸穿过套筒的心轴，该心轴可密封地且可旋转地支撑在套筒和心轴之间进行相对旋转。 心轴和套管具有用于将可泵送物质从外部源连通的流动通道，以通过套筒和心轴排放到顶部驱动动力单元下方的井筒的内部。 该单元可以包括包装注射系统，夹具和新颖的包装配置。
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公开(公告)号：US07500518B2
公开(公告)日：2009-03-10
申请号：US11831475
申请日：2007-07-31
申请人： Kip M. Robichaux , Terry P. Robichaux , Steve Jacobs , Bryan Clement , Murray Pellegrin , Kenneth G. Caillouet , Philip K. Watson
发明人： Kip M. Robichaux , Terry P. Robichaux , Steve Jacobs , Bryan Clement , Murray Pellegrin , Kenneth G. Caillouet , Philip K. Watson
IPC分类号： E21B43/04
CPC分类号： E21B21/00 , E21B17/05 , E21B21/02 , E21B33/05 , F16L27/087
摘要： For use with a top drive power unit supported for connection with a well string in a well bore to selectively impart longitudinal and/or rotational movement to the well string, a feeder for supplying a pumpable substance such as cement and the like from an external supply source to the interior of the well string in the well bore without first discharging it through the top drive power unit including a mandrel extending through a sleeve which is sealably and rotatably supported thereon for relative rotation between the sleeve and mandrel. The mandrel and sleeve have flow passages for communicating the pumpable substance from an external source to discharge through the sleeve and mandrel and into the interior of the well string below the top drive power unit. The unit can include a packing injection system, clamp, and novel packing configuration.
摘要翻译： 为了与支撑用于与井眼中的井串连接的顶部驱动动力单元一起使用以选择性地向井串施加纵向和/或旋转运动，用于从外部供应源供应可泵送物质例如水泥等的进料器 来源于井眼中的井串的内部，而不首先通过顶部驱动动力单元将其排出，该顶部驱动动力单元包括延伸穿过套筒的心轴，该心轴可密封地且可旋转地支撑在套筒和心轴之间进行相对旋转。 心轴和套管具有用于将可泵送物质从外部源连通的流动通道，以通过套筒和心轴排放到顶部驱动动力单元下方的井筒的内部。 该单元可以包括包装注射系统，夹具和新颖的包装配置。
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公开(公告)号：US07007753B2
公开(公告)日：2006-03-07
申请号：US10658092
申请日：2003-09-09
申请人： Kip M. Robichaux , Terry P. Robichaux , Steve Jacobs , Bryan Clement , Murray Pellegrin , Kenneth G. Caillouet , Philip K. Watson
发明人： Kip M. Robichaux , Terry P. Robichaux , Steve Jacobs , Bryan Clement , Murray Pellegrin , Kenneth G. Caillouet , Philip K. Watson
IPC分类号： E21B33/16
CPC分类号： E21B21/00 , E21B17/05 , E21B21/02 , E21B33/05 , F16L27/087
摘要： For use with a top drive power unit supported for connection with a well string in a well bore to selectively impart longitudinal and/or rotational movement to the well string, a feeder for supplying a pumpable substance such as cement and the like from an external supply source to the interior of the well string in the well bore without first discharging it through the top drive power unit including a mandrel extending through a sleeve which is sealably and rotatably supported thereon for relative rotation between the sleeve and mandrel. The mandrel and sleeve have flow passages for communicating the pumpable substance from an external source to discharge through the sleeve and mandrel and into the interior of the well string below the top drive power unit. The unit can include a packing injection system, clamp, and novel packing configuration.
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