摘要:
The present invention relates to novel pharmaceutical compositions of general formula (I) comprising thienopyrimidine compounds. Moreover, the present invention relates to the use of the thienopyrimidine compounds of the invention for the production of pharmaceutical compositions for the prophylaxis and/or treatment of diseases which can be influenced by the inhibition of the kinase activity of Mnk1 and/or Mnk2 (Mnk2a or Mnk2b) and/or variants thereof.
摘要:
The invention relates to a magnet pole for magnetic levitation vehicles, containing an iron core (1), a coil (6) applied thereon, a rear (4) of a magnet lying against a lower contact surface (3) of the iron core (1), and a protective layer (9) that encases the coil (6) and an upper pole surface (2) of the iron core (1). The protective layer (9) has a section (15) made of an elastic material in a lower region of the iron core (1), said section bordering the circumferential surface (5) of the iron core.
摘要:
The invention discloses the use of a compound of formula (I), wherein R1, R2, R3, and R4 each independently represents: hydrogen; halo; hydroxy; (C1-C6) alkyl optionally substituted by hydroxy or (C1-C4) alkoxy; (C1-C6) haloalkyl; (C1-C6) alkoxy; and (C1-C6) haloalkoxy; for the preparation of a medicament for the prevention and/or treatment of diseases resulting from opening of the MPTP which are characterized by degenerative tissue damages, in particular, diabetes and diabetic complications, neurological diseases and stroke, heart infarction, inherited dystrophies and hepatitis, more particularly, diabetic vascular diseases, such as diabetic retinopathy, and neurodegenerative disorders, such as multiple sclerosis. Further objects are a group of selected individual compounds of formula (I) for use as medicaments and a further group of selected individual compounds of formula (I) as novel compounds.
摘要:
A magnet pole for magnetic levitation vehicles includes an iron core (1) having an upper pole surface (2), a lower contact surface (3) for a magnet rear side (4) and a circumferential surface (5) disposed between the pole surface (2) and the contact surface (3). A coil (6) is applied onto the circumferential surface (5) of the iron core (1). An intermediate layer is made of an electrically insulating material, which is disposed between the circumferential surface (5) and the coil (6). A protective layer (9) encapsulates the coil (6). At least the pole surface (2) of the iron core (1) is made of a hard material and abuts the circumferential surface (5) in a lower region of the iron core (1). The protective layer (9) contains a section (15) made of an elastic material in a region adjacent to the circumferential surface (5).
摘要:
The invention discloses the use of a compound of formula (I), wherein R1, R2, R3, and R4 each independently represents: hydrogen; halo; hydroxy; (C1-C6) alkyl optionally substituted by hydroxy or (C1-C4) alkoxy; (C1-C6) haloalkyl; (C1-C6) alkoxy; and (C1-C6) haloalkoxy; for the preparation of a medicament for the prevention and/or treatment of diseases resulting from opening of the MPTP which are characterized by degenerative tissue damages, in particular, diabetes and diabetic complications, neurological diseases and stroke, heart infarction, inherited dystrophies and hepatitis, more particularly, diabetic vascular diseases, such as diabetic retinopathy, and neurodegenerative disorders, such as multiple sclerosis. Further objects are a group of selected individual compounds of formula (I) for use as medicaments and a further group of selected individual compounds of formula (I) as novel compounds.