摘要:
The present invention relates to novel compounds possessing specific hot, pungent and spicy taste when subjected to direct pungency evaluation, which may be useful as food additives and anti-oxidants, however the said compounds do not add to any nutritional value but the synthesised compounds can possess useful pharmacological properties which is expected to find application in new test models for the development of anti-inflammatory drugs, bioavailability enhancers and for the study of hepatic drug metabolising mechanism; also relates to a process for preparing the said compounds.
摘要:
The present invention relates to novel compounds possessing specific hot, pungent and spicy taste when subjected to direct pungency evaluation, which may be useful as food additives and anti-oxidants, however the said compounds do not add to any nutritional value but the synthesised compounds can possess useful pharmacological properties which is expected to find application in new test models for the development of anti-inflammatory drugs, bioavailability enhancers and for the study of hepatic drug metabolising mechanism; also relates to a process for preparing the said compounds.
摘要:
This invention discloses a process for the use of a novel organism belonging to the genus Trichosporon sp. as whole wet or dry cell culture or cell free extract or crude enzyme or pure isolated enzyme The strain of Trichosporon sp. used in the process is designated as RRLY-15 and has been deposited in Deutsche Sammlung von Mikroorganismen und Zellekulturen GmbH (DSMZ). The invention also discloses the preparation of S(+)-6-methoxy-2-naphthalene acetic acid (naproxen) of formula (2) through enantioselective hydrolysis of a racemic mixture of alkyl esters of (±)-6-methoxy-&agr;-methyl-2-naphthalene acetic acid of formula (1) where R represents —CH3,—C2H5,—C3H7,—C4H9 and the like and S(+)- Naproxen is a medicinally important non steroidal anti-inflammatory drug.
摘要翻译:本发明公开了一种使用属于Trichosporon sp。的新生物的方法。 作为整个湿或干细胞培养或无细胞提取物或粗酶或纯分离的酶Trichosporon sp。 在该过程中使用的产品被指定为RRLY-15,并已存放在德意志银行(Mikroorganismen und Zellekulturen GmbH)(DSMZ)。 本发明还公开了通过对映选择性水解(±)-6-甲氧基-α-甲氧基-2-甲基苯基的烷基酯的外消旋混合物制备式(2)的S(+) - 6-甲氧基-2-萘乙酸(萘普生) 式(1)的甲基-2-萘乙酸,其中R表示-CH 3,-C 2 H 5,-C 3 H 7,-C 4 H 9等,而S(+) - 萘普生是药物重要的非甾体抗炎药。
摘要:
The present invention provides a synergistic composition of bioactive fraction essentially constituting iridoid glucosides, acetyl barlerin and shanzhiside methyl ester isolated from a plant source Barleria prionitis linn along with a process for the isolation of the bioactive fraction, the present invention also relates to a method of treating mammals and humans for hepatotoxicity, stress and immuno-deficiency with the synergistic bioactive composition.
摘要:
A novel glucopyranoside, 6-hydroxy-2-p-hydroxybenzylbenzofuran-7-C-&bgr;-D-glucopyranoside of the formula 1 isolated from Pterocarpus marsupium and to a process for the isolation thereof is disclosed. The invention also relates to a pharmaceutical composition containing 6-hydroxy-2-p-hydroxybenzylbenzofuran-7-C-&bgr;-D-glucopyranoside and to method for the treatment of diabetes using said compound.
摘要:
The present invention relates to a pharmaceutical composition comprising a bioactive constituent trans-tetracos-15-enoic acid and a process for the isolation of tetracos-15-enoic acid from the plant Indigofera tinctoria along with a method of treatment for hepatotoxicity.
摘要:
The present invention relates to a process for the isolation of a novel oligospirostanoside structurally constructed as 3-0-[&agr;-L-rhamnopyranosyl-(1→2)-&agr;-L-rhamnopyranosyl-(1→4)-0-&bgr;-D-glucopyranosyl]-25(S)-5&bgr; spirostan-3&bgr;-ol isolated from Asparagus racemosus and biologically evaluated as a potent immunomodulatory agent.
摘要:
The present invention relates to a synergistic hepatoprotective pharmaceutical composition comprising an effective amount of trans-tetracos-15-enoic acid (TCA) and Apocynin (APO), the present invention also relates to a method of treatment for hepatotoxicity in mammals and humans.
摘要:
The present invention relates to a process for isolating plant Argyrobium roseum extract that contains flavonoid glycoside, wherein the extract possesses hypoglycaemic activity. The present invention also contemplates a composition containing the extract and a method of treating various hyperglycaemic conditions including non-insulin dependent diabetes mellitus disease condition by administering the extract.
摘要:
The present invention relates to a process of isolation of bioactive eupalitin (3-O-O-D-galactopyranoside) of formula 1 possessing anti-osteoporosis activity by extraction of powdered leaves of Boerhaavia diffusa, with better yield: