公开(公告)号：US20140099507A1

公开(公告)日：2014-04-10

申请号：US14036619

申请日：2013-09-25

申请人： NATIONAL UNIVERSITY CORPORATION HOKKAIDO UNIVERSITY ,  SUMITOMO BAKELITE COMPANY LIMITED

发明人： Hideyuki SHIMAOKA ,  Shinichiro NISHIMURA ,  Yasuro SHINOHARA ,  Yoshiaki MIURA ,  Jun-ichi FURUKAWA

IPC分类号： C08J3/24

CPC分类号： C08J3/24 ,  C07C233/20 ,  C07C271/08 ,  C07C281/02 ,  C08F8/30 ,  C08F122/38 ,  C08F2222/1013 ,  G01N33/5308 ,  G01N2030/027 ,  G01N2030/8813 ,  G01N2030/8836 ,  Y02P20/55 ,  Y10T428/2982 ,  C08F220/60

摘要： The present invention provides a method for preparing a sample characterized by binding a substance A containing a hydrazide group to a sugar chain and/or a sugar derivative via hydrazone formation between the hydrazide group of the substance A and the reducing end of the sugar chain and/or the sugar derivative thereby to enable the separation and purification of the sugar chain and/or the sugar derivative for an analytical sample from a biological sample containing the sugar chain and/or the sugar derivative by a simple operation.

公开(公告)号：US20140046003A1

公开(公告)日：2014-02-13

申请号：US14036539

申请日：2013-09-25

申请人： Sumitomo Bakelite Company Limited

发明人： Hideyuki SHIMAOKA ,  Shinichiro NISHIMURA ,  Yasuro SHINOHARA ,  Yoshiaki MIURA ,  Jun-ichi FURUKAWA

IPC分类号： C08F122/38

CPC分类号： C08J3/24 ,  C07C233/20 ,  C07C271/08 ,  C07C281/02 ,  C08F8/30 ,  C08F122/38 ,  C08F2222/1013 ,  G01N33/5308 ,  G01N2030/027 ,  G01N2030/8813 ,  G01N2030/8836 ,  Y02P20/55 ,  Y10T428/2982 ,  C08F220/60

摘要： The present invention provides a method for preparing a sample characterized by binding a substance A containing a hydrazide group to a sugar chain and/or a sugar derivative via hydrazone formation between the hydrazide group of the substance A and the reducing end of the sugar chain and/or the sugar derivative thereby to enable the separation and purification of the sugar chain and/or the sugar derivative for an analytical sample from a biological sample containing the sugar chain and/or the sugar derivative by a simple operation.

公开(公告)号：US20140094569A1

公开(公告)日：2014-04-03

申请号：US14036583

申请日：2013-09-25

申请人： NATIONAL UNIVERSITY CORPORATION HOKKAIDO UNIVERSITY ,  SUMITOMO BAKELITE COMPANY LIMITED

发明人： Hideyuki SHIMAOKA ,  Shinichiro NISHIMURA ,  Yasuro SHINOHARA ,  Yoshiaki MIURA ,  Jun-ichi FURUKAWA

IPC分类号： C08F122/38 ,  C07C271/08

CPC分类号： C08J3/24 ,  C07C233/20 ,  C07C271/08 ,  C07C281/02 ,  C08F8/30 ,  C08F122/38 ,  C08F2222/1013 ,  G01N33/5308 ,  G01N2030/027 ,  G01N2030/8813 ,  G01N2030/8836 ,  Y02P20/55 ,  Y10T428/2982 ,  C08F220/60

摘要： The present invention provides a method for preparing a sample characterized by binding a substance A containing a hydrazide group to a sugar chain and/or a sugar derivative via hydrazone formation between the hydrazide group of the substance A and the reducing end of the sugar chain and/or the sugar derivative thereby to enable the separation and purification of the sugar chain and/or the sugar derivative for an analytical sample from a biological sample containing the sugar chain and/or the sugar derivative by a simple operation.

摘要翻译： 本发明提供一种制备样品的方法，其特征在于，通过在物质A的酰肼基和糖链的还原端之间形成腙将含有酰肼基团的物质A与糖链和/或糖衍生物结合， /或糖衍生物，从而能够通过简单的操作从含有糖链和/或糖衍生物的生物样品中分离和纯化分析样品的糖链和/或糖衍生物。