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    Topical composition for skin containing polysaccharide extract of red ginseng
    4.
    发明授权
    Topical composition for skin containing polysaccharide extract of red ginseng 有权
    含有人参多糖提取物的皮肤外用组合物

    公开(公告)号：US08691794B2

    公开(公告)日：2014-04-08

    申请号：US13504682

    申请日：2010-11-23

    申请人： Ji Seong Kim ,  Myeong Hun Yeom ,  Sun Sang Kwon ,  Duck Hee Kim ,  Han Kon Kim

    发明人： Ji Seong Kim ,  Myeong Hun Yeom ,  Sun Sang Kwon ,  Duck Hee Kim ,  Han Kon Kim

    IPC分类号： A01N43/04 ,  A61K31/715

    CPC分类号： A61Q19/08 ,  A61K8/0212 ,  A61K8/73 ,  A61K8/97 ,  A61K36/258

    摘要： The present invention relates to a composition for skin application, which has the effects of reducing skin wrinkles, enhancing skin elasticity and preventing skin aging, and more particularly, to a composition for skin application, which contains, as an active ingredient, a polysaccharide extract of red ginseng having a molecular weight of less than 10,000, in which the polysaccharide extract of red ginseng has the effect of increasing the expression of mitochondrial electron transport system enzymes in human skin keratinocytes to enhance the activity of the skin cells, thereby reducing skin wrinkles, increasing skin elasticity and preventing skin aging.

    摘要翻译： 本发明涉及一种皮肤应用组合物，其具有减轻皮肤皱纹，增强皮肤弹性和防止皮肤老化的效果，更具体地，涉及含有作为活性成分的多糖提取物的皮肤应用组合物 分子量小于10,000的红参中，人参多糖提取物具有增加人皮肤角质形成细胞中线粒体电子传递系统酶表达的作用，以增强皮肤细胞的活性，从而减少皮肤皱纹 ，增加皮肤弹性和防止皮肤老化。

    TOPICAL COMPOSITION FOR SKIN CONTAINING POLYSACCHARIDE EXTRACT OF RED GINSENG
    5.
    发明申请
    TOPICAL COMPOSITION FOR SKIN CONTAINING POLYSACCHARIDE EXTRACT OF RED GINSENG 有权
    用于含有红霉素多糖提取物的皮肤的局部组合物

    公开(公告)号：US20120238743A1

    公开(公告)日：2012-09-20

    申请号：US13504682

    申请日：2010-11-23

    申请人： Ji Seong Kim ,  Myeong Hun Yeom ,  Sun Sang Kwon ,  Duck Hee Kim ,  Han Kon Kim

    发明人： Ji Seong Kim ,  Myeong Hun Yeom ,  Sun Sang Kwon ,  Duck Hee Kim ,  Han Kon Kim

    IPC分类号： C08B37/00

    CPC分类号： A61Q19/08 ,  A61K8/0212 ,  A61K8/73 ,  A61K8/97 ,  A61K36/258

    摘要： The present invention relates to a composition for skin application, which has the effects of reducing skin wrinkles, enhancing skin elasticity and preventing skin aging, and more particularly, to a composition for skin application, which contains, as an active ingredient, a polysaccharide extract of red ginseng having a molecular weight of less than 10,000, in which the polysaccharide extract of red ginseng has the effect of increasing the expression of mitochondrial electron transport system enzymes in human skin keratinocytes to enhance the activity of the skin cells, thereby reducing skin wrinkles, increasing skin elasticity and preventing skin aging.

    摘要翻译： 本发明涉及一种皮肤应用组合物，其具有减轻皮肤皱纹，增强皮肤弹性和防止皮肤老化的效果，更具体地，涉及含有作为活性成分的多糖提取物的皮肤应用组合物 分子量小于10,000的红参中，人参多糖提取物具有增加人皮肤角质形成细胞中线粒体电子传递系统酶表达的作用，以增强皮肤细胞的活性，从而减少皮肤皱纹 ，增加皮肤弹性和防止皮肤老化。

    Percutaneous controlled releasing material using nano-sized polymer particles and external application agent containing the same
    8.
    发明申请
    Percutaneous controlled releasing material using nano-sized polymer particles and external application agent containing the same 审中-公开
    使用纳米尺寸聚合物颗粒的经皮控制释放材料和含有其的外用施用剂

    公开(公告)号：US20090232855A1

    公开(公告)日：2009-09-17

    申请号：US09878712

    申请日：2001-06-11

    申请人： Sun Sang Kwon ,  Byung Hee Yoo ,  Yoon Sung Nam ,  Bae Hwan Kim ,  Bong Seok Ku ,  Sang Hoon Han ,  Ih Seop Chang ,  Jong Suk Lee

    发明人： Sun Sang Kwon ,  Byung Hee Yoo ,  Yoon Sung Nam ,  Bae Hwan Kim ,  Bong Seok Ku ,  Sang Hoon Han ,  Ih Seop Chang ,  Jong Suk Lee

    IPC分类号： A61K8/02 ,  A61K9/14

    CPC分类号： A61K9/5138

    摘要： A percutaneous releasing material and agent having characteristics that include a high stability of an active agent in the formulation, a high topical absorption rate, decreased irritation on the skin, and an increased tactile comfort. The percutaneous releasing material incorporates an external application agent composition that is prepared by using nanometer-sized polymer particles, i.e., particles having a size or diameter between approximately 1 nm and approximately 500 nm, and more preferably having a size between about 30 nm and about 150 nm. Further, the percutaneous releasing material and agent according to the present invention incorporate polymer particles that preferably contain a physiologically active agent that more readily penetrates through the stratum corneum to the upper layer of the dermis, whereby the physiologically active agent is effused into the skin while staying in the upper layer of dermis.

    摘要翻译： 具有包含制剂中活性剂高稳定性，高局部吸收率，对皮肤刺激性降低以及增加的触觉舒适度的特征的经皮释放材料和试剂。 经皮释放材料包含通过使用纳米尺寸聚合物颗粒制备的外用施用剂组合物，即具有约1nm至约500nm之间的尺寸或直径的颗粒，更优选具有约30nm至约30nm的尺寸 150nm。 此外，根据本发明的经皮释放材料和试剂掺入优选含有更容易穿透角质层至生理活性剂的生物活性剂的聚合物颗粒，从而使生理活性剂流入皮肤，同时 留在真皮层的上层。