摘要:
A processes of sterilizing a contact lens, that is immersed in an aqueous liquid and hermetically in a container, using at least 284 mJ/cm2 of UV radiation in the range of 240-280 nm is disclosed herein.
摘要翻译:本文公开了使用在240-280nm范围内的至少284mJ / cm 2的紫外线辐射将隐形眼镜浸入含水液体并气密地在容器中进行灭菌的方法。
摘要:
The application of active ingredients, exemplified by GML, to absorbent fibers, such as rayon fibers, used in tampon manufacture at very low levels has been found to maintain efficacy in the inhibition of the production of toxic shock syndrome toxin one (TSST-1) produced by S. aureus without overtly killing the microorganism to achieve the desired reduction while avoiding undesired test results that suggest the presence of “impurities” in some jurisdictions.
摘要:
Nonabsorbent products and douche compositions for cleansing and placement within the vagina contain an amount of a compound effective to inhibit the production of toxic shock syndrome toxin-1 and Enterotoxins A, B and C when the products are brought into contact with the bacteria. The products and compositions of this invention are also effective in combatting streptococcal pyrogenic exotoxin and hemolysin production by Groups A, B, F and G streptococci. The compound is selected from the group consisting of monoesters of a polyhydric aliphatic alcohol and a C.sub.8 -C.sub.18 fatty acid; diesters of a polyhydric aliphatic alcohol and a C.sub.8 -C.sub.18 fatty acid; and mixtures thereof. The monoesters and diesters have at least one hydroxyl group associated with their aliphatic alcohol residue.
摘要:
Absorbent products, especially catemenial tampons, for absorbing body fluids, such as menstrual fluid, blood and wound exudates, comprise an amount of a compound effective to inhibit the production of Enterotoxin A, Enterotoxin B and/or Enterotoxin C by Staphylococcus aureus bacteria when the products are brought into contact with the bacteria. The compositions of this invention are also useful to inhibit production of Streptococcal pyrogenic exotoxins A, B and C, as well as hemolysins produced by Groups A, B, F and G streptococci in solution as well as being expected to be effective to inhibit such toxin and hemolysin production when used in conjunction with absorbent products. The compound is selected from the group consisting of monoesters of a polyhydric aliphatic alcohol and a C.sub.8 -C.sub.18 fatty acid; diesters of a polyhydric aliphatic alcohol and a C.sub.8 -C.sub.18 fatty acid; and mixtures thereof. The monoesters and diesters have at least one hydroxyl group associated with their aliphatic alcohol residue.
摘要:
This invention provides a process of sterilizing a medical device, and preferably the contents of a sealed container which comprises said medical device, comprising the step of exposing said medical device to monochromatic ultraviolet radiation whereby the Dvalue of Bacillus stearothermophilus (ATCC 7953) is at least 23.7 mJ/cm2 monochromatic ultraviolet radiation at 257 nm to the spore. Further, this invention provides a process of sterilizing a medical device comprising the step of subjecting said medical device to monochromatic ultraviolet radiation wherein the minimum total energy density of said monochromatic ultraviolet radiation at 257 nm which reaches the microorganisms present on said medical device is at least 284 mJ/cm2.This invention further provides an apparatus for delivering UV radiation to a medical device for sterilization comprising a laser and a scanner for the laser such that at least 284 mJ/cm2 at 257 nm is applied to a treatment area for said medical device. This invention provides a process and apparatus in which sterilization can be achieved in less than 20 seconds, preferably less than 15 seconds, more preferably in less than 5 seconds. The process and apparatus are efficient and continuous.
摘要翻译:本发明提供了一种对医疗装置进行灭菌的方法,优选包括所述医疗装置的密封容器的内容物,其包括将所述医疗装置暴露于单色紫外线辐射的步骤,由此使嗜热脂肪芽孢杆菌(ATCC 7953)的D值至少为 在257nm处的23.7mJ / cm 2单色紫外线辐射对孢子。 此外,本发明提供对医疗装置进行灭菌的方法,包括以下步骤:对所述医疗装置进行单色紫外线辐射,其中到达所述医疗装置上存在的微生物的257nm处的所述单色紫外线辐射的最小总能量密度至少为 284mJ / cm 2。 本发明还提供一种用于将UV辐射递送到用于灭菌的医疗装置的装置,包括用于激光的激光器和扫描仪,使得在257nm处的至少284mJ / cm 2施加到所述医疗装置的治疗区域。 本发明提供一种方法和装置,其中可以在少于20秒,优选小于15秒,更优选在少于5秒内实现灭菌。 该方法和设备是有效和连续的。
摘要:
This invention provides a process of sterilizing a medical device, and preferably the contents of a sealed container which comprises said medical device, comprising the step of exposing said medical device to monochromatic ultraviolet radiation whereby the Dvalue of Bacillus stearothermophilus (ATCC 7953) is at least 23.7 mJ/cm2 monochromatic ultraviolet radiation at 257 nm to the spore. Further, this invention provides a process of sterilizing a medical device comprising the step of subjecting said medical device to monochromatic ultraviolet radiation wherein the minimum total energy density of said monochromatic ultraviolet radiation at 257 nm which reaches the microorganisms present on said medical device is at least 284 mJ/cm2.This invention further provides an apparatus for delivering UV radiation to a medical device for sterilization comprising a laser and a scanner for the laser such that at least 284 mJ/cm2 at 257 nm is applied to a treatment area for said medical device. This invention provides a process and apparatus in which sterilization can be achieved in less than 20 seconds, preferably less than 15 seconds, more preferably in less than 5 seconds. The process and apparatus are efficient and continuous.
摘要:
This invention provides a process of sterilizing a medical device, and preferably the contents of a sealed container which comprises said medical device, comprising the step of exposing said medical device to monochromatic ultraviolet radiation whereby the Dvalue of Bacillus stearothermophilus (ATCC 7953) is at least 23.7 mJ/cm2 monochromatic ultraviolet radiation at 257 nm to the spore. Further, this invention provides a process of sterilizing a medical device comprising the step of subjecting said medical device to monochromatic ultraviolet radiation wherein the minimum total energy density of said monochromatic ultraviolet radiation at 257 nm which reaches the microorganisms present on said medical device is at least 284 mJ/cm2.This invention further provides an apparatus for delivering UV radiation to a medical device for sterilization comprising a laser and a scanner for the laser such that at least 284 mJ/cm2 at 257 nm is applied to a treatment area for said medical device. This invention provides a process and apparatus in which sterilization can be achieved in less than 20 seconds, preferably less than 15 seconds, more preferably in less than 5 seconds. The process and apparatus are efficient and continuous.
摘要翻译:本发明提供了一种对医疗装置进行灭菌的方法,优选包括所述医疗装置的密封容器的内容物,其包括将所述医疗装置暴露于单色紫外线辐射的步骤,由此使嗜热脂肪芽孢杆菌(ATCC 7953)的D值至少为 在257nm处的23.7mJ / cm 2单色紫外线辐射对孢子。 此外,本发明提供对医疗装置进行灭菌的方法,包括以下步骤:对所述医疗装置进行单色紫外线辐射,其中到达所述医疗装置上存在的微生物的257nm处的所述单色紫外线辐射的最小总能量密度至少为 284mJ / cm 2。 本发明还提供一种用于将UV辐射递送到用于灭菌的医疗装置的装置,包括用于激光的激光器和扫描仪,使得在257nm处的至少284mJ / cm 2施加到所述医疗装置的治疗区域。 本发明提供一种方法和装置,其中可以在少于20秒,优选小于15秒,更优选在少于5秒内实现灭菌。 该方法和设备是有效和连续的。
摘要:
A composition of matter includes a flexible substrate and a coating disposed on the substrate. The coating comprises about 10-60 wt-% of a waxy compound and about 90-40 wt-% of a diluent. The coating forms a stable liquid mixture at a temperature between about 35° C. and about 100° C., has a liquefaction temperature of at least about 30° C., and has a contact angle with a flat surface of the substrate of less than about 35° when measured at a temperature of 60° C.
摘要:
The application of active ingredients, exemplified by GML, to absorbent fibers, such as rayon fibers, used in tampon manufacture at very low levels has been found to maintain efficacy in the inhibition of the production of toxic shock syndrome toxin one (TSST-1) produced by S. aureus without overtly killing the microorganism to achieve the desired reduction while avoiding undesired test results that suggest the presence of “impurities” in some jurisdictions.
摘要:
A composition of matter includes a flexible substrate and a coating disposed on the substrate. The coating comprises about 10-60 wt-% of a waxy compound and about 90-40 wt-% of a diluent. The coating forms a stable liquid mixture at a temperature between about 35° C. and about 100° C., has a liquefaction temperature of at least about 30° C., and has a contact angle with a flat surface of the substrate of less than about 35° when measured at a temperature of 60° C.