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1.发明申请LONG-ACTING INJECTABLE MOXIDECTIN FORMULATIONS AND NOVEL MOXIDECTIN CRYSTAL FORMS 有权长效注射胶体制剂和新型MOXIDECTIN晶体形式公开(公告)号：US20130143956A1
公开(公告)日：2013-06-06
申请号：US13690185
申请日：2012-11-30
IPC分类号： A61K31/365
CPC分类号： A61K31/365 , A61K9/0024 , A61P33/00 , C07D493/22
摘要： This invention provides for novel antiparasitic and pesticidal forms of moxidectin, including a long-acting polymeric implant. The resulting compounds may be used in veterinary compositions which are used in treating, controlling and preventing of endo- and ectoparasite infections in animals.
摘要翻译： 本发明提供了莫昔克丁的新型抗寄生虫和杀虫剂形式，包括长效聚合物植入物。 所得化合物可用于兽用组合物，其用于治疗，控制和预防动物内和外寄生虫感染。
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2.发明授权Long-acting injectable moxidectin formulations and novel moxidectin crystal forms 有权长效注射莫昔克丁配方和新型莫昔克丁晶体形式公开(公告)号：US09044453B2
公开(公告)日：2015-06-02
申请号：US14225187
申请日：2014-03-25
IPC分类号： A61K31/365 , C07D493/22
CPC分类号： A61K31/365 , A61K9/0024 , A61P33/00 , C07D493/22
摘要： This invention provides for novel antiparasitic and pesticidal forms of moxidectin, including a long-acting polymeric implant. The resulting compounds may be used in veterinary compositions which are used in treating, controlling and preventing of endo- and ectoparasite infections in animals.
摘要翻译： 本发明提供了莫昔克丁的新型抗寄生虫和杀虫剂形式，包括长效聚合物植入物。 所得化合物可用于兽用组合物，其用于治疗，控制和预防动物内和外寄生虫感染。
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3.发明授权Long-acting injectable moxidectin formulations and novel moxidectin crystal forms 有权长效注射莫昔克丁配方和新型莫昔克丁晶体形式公开(公告)号：US08715711B2
公开(公告)日：2014-05-06
申请号：US13690185
申请日：2012-11-30
CPC分类号： A61K31/365 , A61K9/0024 , A61P33/00 , C07D493/22
摘要： This invention provides for novel antiparasitic and pesticidal forms of moxidectin, including a long-acting polymeric implant. The resulting compounds may be used in veterinary compositions which are used in treating, controlling and preventing of endo- and ectoparasite infections in animals.
摘要翻译： 本发明提供了莫昔克丁的新型抗寄生虫和杀虫剂形式，包括长效聚合物植入物。 所得化合物可用于兽用组合物，其用于治疗，控制和预防动物内和外寄生虫感染。
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4.发明申请LONG-ACTING INJECTABLE MOXIDECTIN FORMULATIONS AND NOVEL MOXIDECTIN CRYSTAL FORMS 有权长效注射胶体制剂和新型MOXIDECTIN晶体形式公开(公告)号：US20140323559A1
公开(公告)日：2014-10-30
申请号：US14225187
申请日：2014-03-25
IPC分类号： A61K31/365
CPC分类号： A61K31/365 , A61K9/0024 , A61P33/00 , C07D493/22
摘要： This invention provides for novel antiparasitic and pesticidal forms of moxidectin, including a long-acting polymeric implant. The resulting compounds may be used in veterinary compositions which are used in treating, controlling and preventing of endo- and ectoparasite infections in animals.
摘要翻译： 本发明提供了莫昔克丁的新型抗寄生虫和杀虫剂形式，包括长效聚合物植入物。 所得化合物可用于兽用组合物，其用于治疗，控制和预防动物内和外寄生虫感染。
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公开(公告)号：US6156894A
公开(公告)日：2000-12-05
申请号：US275333
申请日：1999-03-24
IPC分类号： A61K31/00 , A61K31/505 , A61K31/513 , A61P13/00 , A61P13/08 , A61P43/00 , C07D239/54 , C07D239/553 , C07D239/46
CPC分类号： C07D239/54 , C07D239/553
摘要： A process is useful for making compounds of the formula: wherein R is hydro, methyl, or fluoro.Valuable intermediates in this process include: ##STR1## wherein R is hydro, methyl, or fluoro, and L is a leaving group.
摘要翻译： 一种方法可用于制备下式的化合物：其中R是氢，甲基或氟。 该方法中有价值的中间体包括：其中R是氢，甲基或氟，L是离去基团。
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